Browse
Records Added in 2021
Records added in 2021
Change year: 2018 | 2019 | 2020 | 2021 | 2022 | 2023 | 2024
Filter by month: January | February | March | April | May | June | July | August | September | October | November | December
Showing records 101 to 125 of 798. [First] Page: 1 2 3 4 5 6 7 8 9 Last
Ad-Dressing Stem Cells: Hydrogels for Encapsulation
Leonidas Kandilogiannakis, Eirini Filidou, George Kolios, Vasilis Paspaliaris
August 2, 2021 (v1)
Subject: Biosystems
Keywords: biomaterials, encapsulation, hydrogels, stem cells
Regenerative medicine is a novel scientific field that employs the use of stem cells as cell-based therapy for the regeneration and functional restoration of damaged tissues and organs. Stem cells bear characteristics such as the capacity for self-renewal and differentiation towards specific lineages and, therefore, serve as a backup reservoir in case of tissue injuries. Therapeutically, they can be autologously or allogeneically transplanted for tissue regeneration; however, allogeneic stem cell transplantation can provoke host immune responses leading to a host-versus-transplant reaction. A probable solution to this problem is stem cell encapsulation, a technique that utilizes various biomaterials for the creation of a semi-permeable membrane that encases the stem cells. Stem cell encapsulation can be accomplished by employing a great variety of natural and/or synthetic hydrogels and offers many benefits in regenerative medicine, including protection from the host’s immune system and... [more]
Quantitative Determination of Vitamins A and E in Ointments Using Raman Spectroscopy
Sylwester Mazurek, Kamil Pichlak, Roman Szostak
August 2, 2021 (v1)
Keywords: chemometrics, multivariate calibration, ointments, quantitative analysis, Raman spectroscopy, vitamin A, vitamin E
A quantitative analysis of vitamins A and E in commercial ointments containing 0.044% and 0.8% (w/w) of active pharmaceutical ingredients, respectively, was performed using partial least squares models based on FT Raman spectra. Separate calibration systems were prepared to determine the amount of vitamin A in a petrolatum base ointment and to quantify vitamins A and E in a eucerin base one. Compositions of the laboratory-prepared and commercial samples were controlled through a principal component analysis. Relative standard errors of prediction were calculated to compare the predictive ability of the obtained regression models. For vitamin A determination, these errors were found to be in the 3.8−5.0% and 5.7−5.9% ranges for the calibration and validation data sets, respectively. In the case of vitamin E modeling, these errors amounted to 3.7% and 4.4%. On the basis of elaborated models, vitamins A and E were successfully quantified in two commercial products with recoveries in the 9... [more]
Microalgae Biomolecules: Extraction, Separation and Purification Methods
Priscila S. Corrêa, Wilson G. Morais Júnior, António A. Martins, Nídia S. Caetano, Teresa M. Mata
August 2, 2021 (v1)
Subject: Biosystems
Keywords: biomolecules, cell disruption, chromatography, microalgae, purification, supercritical fluids
Several microalgae species have been exploited due to their great biotechnological potential for the production of a range of biomolecules that can be applied in a large variety of industrial sectors. However, the major challenge of biotechnological processes is to make them economically viable, through the production of commercially valuable compounds. Most of these compounds are accumulated inside the cells, requiring efficient technologies for their extraction, recovery and purification. Recent improvements approaching physicochemical treatments (e.g., supercritical fluid extraction, ultrasound-assisted extraction, pulsed electric fields, among others) and processes without solvents are seeking to establish sustainable and scalable technologies to obtain target products from microalgae with high efficiency and purity. This article reviews the currently available approaches reported in literature, highlighting some examples covering recent granted patents for the microalgae’s compone... [more]
Static and Dynamic Analysis of a 6300 KN Cold Orbital Forging Machine
Zhiqiang Gu, Mingzhang Chen, Chaoyang Wang, Wuhao Zhuang
August 2, 2021 (v1)
Keywords: cold orbital forging, dynamic model, experimental analysis, finite element analysis, machine vibration, numerical simulation, static analysis, theoretical analysis
In cold orbital forging (COF) processes, large stress, displacement and vertical vibration of the COF machine are bad for the quality of the part and the fatigue life of the COF machine. It is necessary to investigate the static and dynamic performance of the COF machine and provide methods for reducing the stress, displacement and vertical vibration of the COF machine. In this paper, finite element analysis, theoretical analysis, numerical simulation and experimental analysis were applied to study the static and dynamic performance of a 6300 KN COF machine. The static and dynamic analyses were verified effectively by carrying out strain and vertical vibration test experiments. In the static analysis, the large stress and displacement positions of the COF machine were mainly distributed near the working table and the junction between the working table and the column. Large stress and displacement will be bad for the quality of the part and the fatigue life of the COF machine. Structura... [more]
Microscopic Characteristics and Properties of Fe-Based Amorphous Alloy Compound Reinforced WC-Co-Based Coating via Plasma Spray Welding
Yan Xu, Yinfeng Wang, Yi Xu, Mingyong Li, Zheng Hu
August 2, 2021 (v1)
Subject: Materials
Keywords: Fe-based amorphous alloy, microstructure and properties, plasma spray welding, WC-Co coating
Plasma spray welding, as one of the material surface strengthening techniques, has the advantages of low alloy material consumption, high mechanical properties and good coating compactness. Here, the Co alloy, WC and Fe-based amorphous alloy composite coating is prepared by the plasma spray welding method, and the coating characteristics are investigated. The results indicate that the coatings have a full metallurgical bond in the coating/substrate interface, and the powder composition influences the microstructures and properties of the coating. The hardness of coatings increases with the mass fraction of the Fe-based amorphous alloy. The spray welding layer has a much higher wear resistance compared with the carbon steel, and the Fe-20 exhibits a superior wear resistance when compared to others. The results indicate that the amorphous alloy powders are an effective additive to prepare the coating by plasma spray welding for improving the wear resistance of the coating.
A Model of Transport of Particulate Biomass in a Stream of Fluid
Tomasz Reguła, Jarosław Frączek, Jakub Fitas
August 2, 2021 (v1)
Keywords: air stream, Modelling, particle motion, pneumatic separation, two-phase mixtures
The motion of a solid particle introduced into a stream of fluid is a crucial problem in the contexts of pneumatic transport and the purification and separation of non-uniform mixtures. However, the complexity of the underlying equations of motion enforces the creation of semi-empirical models. Therefore, analysis of particle motion in a pneumatic channel was performed. To reduce the number of independent variables, several simplifying assumptions were made in regard to both the particle and the stream. The resulting model provides trajectory equations for a particle introduced into the stream at given values of the initial angle and initial velocity, which are then solved using numerical integration methods. A hodograph function was formulated on the basis of the Runge−Kutta and NDFs methods to test the correctness of the solutions under various initial parameters and to provide a universal method of solving the equations of motion. To verify the model, terminal velocities were measur... [more]
Relationships between the Number and Power of Hungarian Household-Sized Photovoltaic Power Plants and Selected Indicators of the Settlements: A Case Study
Nóra Hegedűsné Baranyai, Henrik Zsiborács, András Vincze, Nóra Rodek, Martina Makai, Gábor Pintér
August 2, 2021 (v1)
Keywords: economic, Hungary, infrastructural settlement indicators, photovoltaic system, small-scale power plant, solar energy
In the global transformation of energy systems, solar energy plays a prominent role, since the energy from our star is a limitless and clean resource, which is available practically almost everywhere. In spite of the immense advancements of photovoltaic systems, which utilize this source of energy, no in-depth research has been carried out regarding the present Hungarian status of the small-scale photovoltaic power plants, the most common type of solar power plant in Hungary. The novelty of this study is that it examines the number and power of these small-scale power plants at the settlement level within the service areas of the various distribution companies, by also considering the economic and infrastructural dimensions of the settlements. The paper seeks answers to the questions whether there are any significant relationships between the number and the power of power plants of this type and the indicators of the settlements, and if so, how strong they are. Besides pairwise correla... [more]
Optimising Tropical Fruit Juice Quality Using Thermosonication-Assisted Extraction via Blocked Face-Centered Composite Design
Norazlin Abdullah, Nyuk Ling Chin
August 2, 2021 (v1)
Keywords: guava, pomelo, response surface methodology, soursop, ultrasound
Extraction of tropical fruit juice using simple, efficient, and environmentally friendly technologies is gaining importance to produce high quality juices. Juice from pink-fleshed guava, pink-fleshed pomelo, and soursop was extracted using direct and indirect thermosonication methods by varying intensity, time, and temperature, and compared to those extracted using water bath incubation. Improvised models of juice yield, ascorbic acid, and total soluble solids responses were generated by eliminating insignificant model terms of the factors in full quadratic model using backward eliminating procedure. Main effects, 3D, or 4D plots for each response were developed based on factors that influenced the response. Results showed that the best extraction method for guava and pomelo juices were within indirect thermosonication method of 1 kW, 55 °C and 30 min, and 2.5 kW, 54 °C and 23 min, respectively. Direct thermosonication method at 10% amplitude, 55 °C for 2 to 10 min was more suitable fo... [more]
Time of Flight Size Control of Carbon Nanoparticles Using Ar+CH4 Multi-Hollow Discharge Plasma Chemical Vapor Deposition Method
Sung Hwa Hwang, Kazunori Koga, Yuan Hao, Pankaj Attri, Takamasa Okumura, Kunihiro Kamataki, Naho Itagaki, Masaharu Shiratani, Jun-Seok Oh, Susumu Takabayashi, Tatsuyuki Nakatani
August 2, 2021 (v1)
Subject: Materials
Keywords: carbon nanoparticle, coagulation, optical emission spectroscopy, plasma chemical vapor deposition
As the application of nanotechnology increases continuously, the need for controlled size nanoparticles also increases. Therefore, in this work, we discussed the growth mechanism of carbon nanoparticles generated in Ar+CH4 multi-hollow discharge plasmas. Using the plasmas, we succeeded in continuous generation of hydrogenated amorphous carbon nanoparticles with controlled size (25−220 nm) by the gas flow. Among the nanoparticle growth processes in plasmas, we confirmed the deposition of carbon-related radicals was the dominant process for the method. The size of nanoparticles was proportional to the gas residence time in holes of the discharge electrode. The radical deposition developed the nucleated nanoparticles during their transport in discharges, and the time of flight in discharges controlled the size of nanoparticles.
The Effect of Slurry Wet Mixing Time, Thermal Treatment, and Method of Electrode Preparation on Membrane Capacitive Deionisation Performance
Ebrahiem Botha, Nafeesah Smith, Bongibethu Hlabano-Moyo, Bernard Bladergroen
August 2, 2021 (v1)
Subject: Other
Keywords: capacitive deionisation, contact angle, maximum salt adsorption capacity, thermal treatment, wet mixing
Capacitive deionisation (CDI) electrodes with identical composition were prepared using three deposition methods: (1) slurry infiltration by calendering (SIC), (2) ink infiltration dropwise (IID), and (3) ink deposition by spray coating (IDSC). The SIC method clearly showed favourable establishment of an electrode with superior desalination capacity. Desalination results showed that electrodes produced from slurries mixed longer than 30 min displayed a significant reduction in the maximum salt adsorption capacity, due to the agglomeration of carbon black. The electrodes were then thermally treated at 130, 250, and 350 °C. Polyvinylidene difluoride (PVDF) decomposition was observed when the electrodes were treated at temperatures higher than 180 °C. The electrodes treated at 350 °C showed contact angles of θ = 0°. The optimised electrodes showed a salt adsorption capacity value of 24.8 mg/g (130 °C). All CDI electrodes were analysed using specific surface area by N2 adsorption, contact... [more]
Prototype of the Runway Monitoring Process at Smaller Airports: Edvard Rusjan Airport Maribor
Boštjan Kovačič, Damjan Želodec, Damjan Doler
July 29, 2021 (v1)
Keywords: airport, deformations, FWD, geo-information model, geodesy, measurements, monitoring, vertical deviations
The last 20-year announcement predicts a 3.5% increase in the number of yearly passengers which will result in the doubling of the number of passengers in air transport by 2037. Such anticipation indicates the need for efficient monitoring of airport infrastructure as the support of opportune and efficient maintenance works. The novelties of this article are a process model of maintenance and monitoring, suitable for smaller and less burdened airports, and the methodology of monitoring of runways by implementation of the geodetic and geomechanics falling weight deflectometer (FWD) method. In addition, the results confirm the assumption that a specific environment such as an airport allows for sufficiently reliable determination of deformation areas or areas of vertical deviations of runways in a relative short time period available for measurements by using geodetic methods only or by combining other methods; our research model includes the FWD method. With the research, we have also s... [more]
Mixing of Particles in a Rotating Drum with Inclined Axis of Rotation
Parag Widhate, Haiping Zhu, Qinghua Zeng, Kejun Dong
July 29, 2021 (v1)
Keywords: discrete element method, Mixing, rotating drum
Various experimental and numerical studies have been carried out to study the mixing processes inside rotating drums with a horizontal axis of rotation in the past, but little effort has been made to investigate the rotating drums with an inclined axis of rotation, though such inclined drums exist in industrial waste management, food processing, power and pharmaceutical industries. To fill this gap, in this work, the discrete element method was used to study the mixing phenomena of a rotating drum for different angles of inclination from 0° to 15°. It was found that for inclined rotating drums, the whole bed Lacey mixing index is higher than that for the horizontal drum by 7.2% when the angle of inclination is 10°. The mixing index is related to the area ratio of the active region to the whole bed and volumetric fill. Increase in volumetric fill would lead to the decrease of the mixing index. The mixing index and area ratio exhibit similar patterns along the length of the drum for diff... [more]
Comparative Study on CFD Turbulence Models for the Flow Field in Air Cooled Radiator
Chao Yu, Xiangyao Xue, Kui Shi, Mingzhen Shao, Yang Liu
July 29, 2021 (v1)
Keywords: Computational Fluid Dynamics, engine compartment, heat transfer, turbulent model, vortex
This paper compares the performances of three Computational Fluid Dynamics (CFD) turbulence models, Reynolds Average Navier-Stokes (RANS), Detached Eddy Simulation (DES), and Large Eddy Simulation (LES), for simulating the flow field of a wheel loader engine compartment. The distributions of pressure fields, velocity fields, and vortex structures in a hybrid-grided engine compartment model are analyzed. The result reveals that the LES and DES can capture the detachment and breakage of the trailing edge more abundantly and meticulously than RANS. Additionally, by comparing the relevant calculation time, the feasibility of the DES model is proved to simulate the three-dimensional unsteady flow of engine compartment efficiently and accurately. This paper aims to provide a guiding idea for simulating the transient flow field in the engine compartment, which could serve as a theoretical basis for optimizing and improving the layout of the components of the engine compartment.
Subspace Based Model Identification for an Industrial Bioreactor: Handling Infrequent Sampling Using Missing Data Algorithms
Nikesh Patel, Brandon Corbett, Johan Trygg, Chris McCready, Prashant Mhaskar
July 29, 2021 (v1)
Keywords: data driven model identification, missing data, subspace identification
This manuscript addresses the problem of modeling an industrial (Sartorius) bioreactor using process data. In the context of the Sartorius Bioreactor, it is important to appropriately address the problem of dealing with a large number of variables, which are not always measured or are measured at different sampling rates, without taking recourse to simpler interpolation- or imputation-based approaches. To this end, a dynamic model for the Sartorius Bioreactor is developed via appropriately adapting a recently presented subspace model identification technique, which in turn uses nonlinear iterative partial least squares (NIPALS) algorithms to gracefully handle the missing data. The other key contribution is evaluating the ability of the identification approach to provide insight into the process by computing interpretable variables such as metabolite rates. The results demonstrate the ability of the proposed approach to model data from the Sartorius Bioreactor.
Characterization of a Wireless Vacuum Sensor Prototype Based on the SAW-Pirani Principle
Sofia Toto, Mazin Jouda, Jan G. Korvink, Suparna Sundarayyan, Achim Voigt, Hossein Davoodi, Juergen J. Brandner
July 29, 2021 (v1)
Keywords: compact, Pirani, SAW, sensing, vacuum, wireless
A prototype of a wireless vacuum microsensor combining the Pirani principle and surface acoustic waves (SAW) with extended range and sensitivity was designed, modelled, manufactured and characterised under different conditions. The main components of the prototype are a sensing SAW chip, a heating coil and an interrogation antenna. All the components were assembled on a 15 mm × 11 mm × 3 mm printed circuit board (PCB). The behaviour of the PCB was characterised under ambient conditions and in vacuum. The quality of the SAW interrogation signal, the frequency shift and the received current of the coil were measured for different configurations. Pressures between 0.9 and 100,000 Pa were detected with sensitivities between 2.8 GHz/Pa at 0.9 Pa and 1 Hz/Pa close to atmospheric pressure. This experiment allowed us to determine the optimal operating conditions of the sensor and the integration conditions inside a vacuum chamber in addition to obtaining a pressure-dependent signal.
Flow and Diffusion Characteristics of Typical Halon Extinguishing Agent Substitute under Different Release Pressures
Jiaming Jin, Renming Pan, Ruiyu Chen, Xiaokang Xu, Quanwei Li
July 29, 2021 (v1)
Subject: Other
Keywords: aircraft weight reduction, diffusion, flow, Halon candidate substitute, HFC-125, release pressure
To provide guidance towards reducing the weight of the HFC-125 storage vessel by reducing the release pressure and to reveal the effects of release pressure on the extinguishing efficiency of HFC-125, we investigated the flow and diffusion characteristics of HFC-125 under six release pressures in the present study. The influence of release pressure on the degree of superheat, injection duration, pressure loss, jet angle, and concentration distribution were analyzed. Results show that the degree of superheat and the injection duration both decreased with the release pressure. The bubble expansion in the HFC-125 could slow down the pressure decrease in the storage vessel. The flow process in the pipeline can be divided into three phases: pipeline filling, stable flow, and mixed gases release. Both of the maximum and mean values of the pipeline pressure loss increased with the release pressure. The maximum concentration value decreased with the increase of the distance from the nozzle. Th... [more]
Iron-Based Catalytically Active Complexes in Preparation of Functional Materials
Katarzyna Rydel-Ciszek, Tomasz Pacześniak, Izabela Zaborniak, Paweł Błoniarz, Karolina Surmacz, Andrzej Sobkowiak, Paweł Chmielarz
July 29, 2021 (v1)
Keywords: “green” oxidants, controlled radical polymerization, heterogeneous catalysis, homogeneous catalysis, iron-based catalysts, oxidation processes
Iron complexes are particularly interesting as catalyst systems over the other transition metals (including noble metals) due to iron’s high natural abundance and mediation in important biological processes, therefore making them non-toxic, cost-effective, and biocompatible. Both homogeneous and heterogeneous catalysis mediated by iron as a transition metal have found applications in many industries, including oxidation, C-C bond formation, hydrocarboxylation and dehydration, hydrogenation and reduction reactions of low molecular weight molecules. These processes provided substrates for industrial-scale use, e.g., switchable materials, sustainable and scalable energy storage technologies, drugs for the treatment of cancer, and high molecular weight polymer materials with a predetermined structure through controlled radical polymerization techniques. This review provides a detailed statement of the utilization of homogeneous and heterogeneous iron-based catalysts for the synthesis of bo... [more]
An Integrated Approach to the Design of Centralized and Decentralized Biorefineries with Environmental, Safety, and Economic Objectives
Antioco López-Molina, Debalina Sengupta, Claire Shi, Eman Aldamigh, Maha Alandejani, Mahmoud M. El-Halwagi
July 29, 2021 (v1)
Keywords: biorefining, CAPEX correlation, centralized facilities, distributed manufacturing, integration, sustainable design
Biorefineries provide economic, environmental, and social benefits towards sustainable development. Because of the relatively small size of typical biorefineries compared to oil and gas processes, it is necessary to evaluate the options of decentralized (or distributed) plants that are constructed near the biomass resources and product markets versus centralized (or consolidated) facilities that collect biomass from different regions and distribute the products to the markets, benefiting from the economy of scale but suffering from the additional transportation costs. The problem is further compounded when, in addition to the economic factors, environmental and safety aspects are considered. This work presents an integrated approach to the design of biorefining facilities while considering the centralized and decentralized options and the economic, environmental, and safety objectives. A superstructure representation is constructed to embed the various options of interest. A mathematic... [more]
The Effects of Biofertilizers on Growth, Soil Fertility, and Nutrients Uptake of Oil Palm (Elaeis Guineensis) under Greenhouse Conditions
Aaronn Avit Ajeng, Rosazlin Abdullah, Marlinda Abdul Malek, Kit Wayne Chew, Yeek-Chia Ho, Tau Chuan Ling, Beng Fye Lau, Pau Loke Show
July 29, 2021 (v1)
Keywords: biofertilizers, chemical fertilizer, oil palm seedlings nursery, plant growth promoting rhizobacteria
The full dependency on chemical fertilizers in oil palm plantation poses an enormous threat to the ecosystem through the degradation of soil and water quality through leaching to the groundwater and contaminating the river. A greenhouse study was conducted to test the effect of combinations of biofertilizers with chemical fertilizer focusing on the soil fertility, nutrient uptake, and the growth performance of oil palms seedlings. Soils used were histosol, spodosol, oxisol, and ultisol. The three treatments were T1: 100% chemical fertilizer (NPK 12:12:17), T2: 70% chemical fertilizer + 30% biofertilizer A (CF + BFA), and T3: 70% + 30% biofertilizer B (CF + BFB). T2 and T3, respectively increased the growth of oil palm seedlings and soil nutrient status but seedlings in oxisol and ultisol under T3 had the highest in almost all parameters due to the abundance of more efficient PGPR. The height of seedlings in ultisol under T3 was 22% and 17% more than T2 and T1 respectively, with enhance... [more]
Ultrasonically Induced Polymerization and Polymer Grafting in the Presence of Carbonaceous Nanoparticles
Sarah Cohen, Evgeni Zelikman, Ran Yosef Suckeveriene
July 29, 2021 (v1)
Subject: Materials
Keywords: grafting, nanoparticles, polymerization, sonochemistry
Nanotechnology refers to technologies using at least one nanometric dimension. Most advances have been in the field of nanomaterials used in research and industry. The vast potential of polymeric nanocomposites for advanced materials and applications such as hybrid nanocomposites with customized electrical conductivity, anti-bacterial, anti-viral, and anti-fog properties have attracted considerable attention. The number of studies on the preparation of nanocomposites in the presence of carbon materials, i.e., carbon nanotubes (CNTs) and graphene, has intensified over the last decade with the growing interest in their outstanding synergic properties. However, the functionality of such nanocomposites depends on overcoming three key challenges: (a) the breakdown of nanoparticle agglomerates; (b) the attachment of functional materials to the nanoparticle surfaces; and (c) the fine dispersion of functional nanoparticles within the polymeric matrices. Ultrasonic polymerization and grafting i... [more]
Experimental Study on Ramp Shock Wave Control in Ma3 Supersonic Flow Using Two-Electrode SparkJet Actuator
Wei Xie, Zhenbing Luo, Yan Zhou, Lin Wang, Wenqiang Peng, Tianxiang Gao
July 29, 2021 (v1)
Keywords: dynamic pressure measurement, schlieren images, shock wave control, SparkJet actuator, supersonic flow
The control of a shock wave produced by a ramp (ramp shock) in Ma3 supersonic flow using a two-electrode SparkJet (SPJ) actuator in a single-pulse mode is studied experimentally. Except for schlieren images of the interaction process of SPJ with the flow field, a dynamic pressure measurement method is also used in the analysis of shock wave control. In a typical experimental case, under the control of single-pulsed SPJ, the characteristic of ramp shock changes from “short-term local upstream motion” in the initial stage to “long-term whole downstream motion” in the later stage. The angle and position of the ramp shock changes significantly in the whole control process. In addition, the dynamic pressure measurement result shows that the ramp pressure is reduced by a maximum of 79% compared to that in the base flow field, which indicates that the ramp shock is significantly weakened by SPJ. The effects of some parameters on the control effect of SPJ on the ramp shock are investigated and... [more]
A Review of Process Systems Engineering (PSE) Tools for the Design of Ionic Liquids and Integrated Biorefineries
Nishanth G. Chemmangattuvalappil, Denny K. S. Ng, Lik Yin Ng, Jecksin Ooi, Jia Wen Chong, Mario R. Eden
July 29, 2021 (v1)
Keywords: integrated biorefineries, ionic liquids, molecular design, process optimization, process systems engineering
In this review paper, a brief overview of the increasing applicability of Process Systems Engineering (PSE) tools in two research areas, which are the design of ionic liquids and the design of integrated biorefineries, is presented. The development and advances of novel computational tools and optimization approaches in recent years have enabled these applications with practical results. A general introduction to ionic liquids and their various applications is presented followed by the major challenges in the design of optimal ionic liquids. Significant improvements in computational efficiency have made it possible to provide more reliable data for optimal system design, minimize the production cost of ionic liquids, and reduce the environmental impact caused by such solvents. Hence, the development of novel computational tools and optimization tools that contribute to the design of ionic liquids have been reviewed in detail. A detailed review of the recent developments in PSE applicat... [more]
VectorDisk: A Microfluidic Platform Integrating Diagnostic Markers for Evidence-Based Mosquito Control
Sebastian Hin, Desirée Baumgartner, Mara Specht, Jan Lüddecke, Ehsan Mahmodi Arjmand, Benita Johannsen, Larissa Schiedel, Markus Rombach, Nils Paust, Felix von Stetten, Roland Zengerle, Nadja Wipf, Pie Müller, Konstantinos Mavridis, John Vontas, Konstantinos Mitsakakis
July 29, 2021 (v1)
Subject: Biosystems
Keywords: arboviruses, insecticide resistances, LabDisk, malaria, microfluidics, mosquito monitoring, vector-borne diseases
Effective mosquito monitoring relies on the accurate identification and characterization of the target population. Since this process requires specialist knowledge and equipment that is not widely available, automated field-deployable systems are highly desirable. We present a centrifugal microfluidic cartridge, the VectorDisk, which integrates TaqMan PCR assays in two feasibility studies, aiming to assess multiplexing capability, specificity, and reproducibility in detecting disk-integrated vector-related assays. In the first study, pools of 10 mosquitoes were used as samples. We tested 18 disks with 27 DNA and RNA assays each, using a combination of multiple microfluidic chambers and detection wavelengths (geometric and color multiplexing) to identify mosquito and malaria parasite species as well as insecticide resistance mechanisms. In the second study, purified nucleic acids served as samples to test arboviral and malaria infective mosquito assays. Nine disks were tested with 14 as... [more]
Pharmacoeconomic Analysis of Hemophilia Care in Romania
Petre Serban, Brigitha Vlaicu, Margit Serban, Cristina Emilia Ursu, Adina Traila, Cristian Jinca, Jenel Marian Patrascu, Daniel Andrei, Andrei Kozma, Teodora Smaranda Arghirescu
July 29, 2021 (v1)
Subject: Biosystems
Keywords: hemophilia, ICER, socio-economic burden
Hemophilia, a congenital X linked disease, has the serious burden of bleeding, requiring life-long replacement with coagulation factors (CF). In the present day, there is a continuously improving treatment for this condition. Objective: Our observational, cross-sectional study aims at finding out whether a prophylactic replacement with CF is affordable from the point of view of its cost-effectiveness in our country. Material and methods: A cohort of 122 persons with hemophilia were included in this patient-reported outcome survey, and they answered a questionnaire consisting of 56 items, focused on 4 domains—socio-demographic, medical, quality of health/life and cost/cost-effectiveness. Results and discussion: The markers for quality of health/life were correlated with the direct and indirect costs of care, comparing subgroup 1 of patients with prophylactic vs. subgroup 2 with on-demand replacement. Based on the incremental quality adjusted life years and the incremental costs, we calc... [more]
Experimental Study on the Flow and Heat Transfer of Graphene-Based Lubricants in a Horizontal Tube
Zhongpan Cai, Maocheng Tian, Guanmin Zhang
July 29, 2021 (v1)
Subject: Materials
Keywords: convection heat transfer, graphene, nanofluid, thermal conductivity
To improve the heat transfer characteristics of lubricant, graphene-based lubricants were prepared by adding graphene particles, due to its advantages of excellent thermal conductivity and two-dimensional sheet structure. In the present study, its physical properties were measured. A flow heat transfer experiment platform was built to study the flow and heat transfer characteristics of the graphene lubricating oil in a horizontal circular tube. The results show that the graphene lubricant prepared using a two-step approach had good stability, and the dispersibility was good without the agglomeration phenomenon, according to measurements undertaken using an electron microscope and centrifuge. The thermal conductivity and viscosity of graphene lubricant increased with the increase of the graphene concentration, and the thermal conductivity of graphene lubricant with the same concentration decreased with the increase of temperature. When the concentration was equal, the convective heat tr... [more]
Showing records 101 to 125 of 798. [First] Page: 1 2 3 4 5 6 7 8 9 Last
Change year: 2018 | 2019 | 2020 | 2021 | 2022 | 2023 | 2024
Filter by month: January | February | March | April | May | June | July | August | September | October | November | December