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A Stochastic c-Myc Regulated Model of CD8+ T Cell Dynamics and Lineage Tracking
Seyedeh Fatemeh Seyyedizadeh, David A Christian, Thomas A Adams II
October 3, 2026 (v1)
Subject: Biosystems
Keywords: effector cell, Fate mapping, Memory cell, Modelling, T cell, Vaccine
This is the MATLAB source code for a stochastic agent-based model of CD8+ T cell responses following vaccination. The model simulates T cell activation, proliferation, contraction, and differentiation into effector and memory populations. Cell division is regulated by intracellular c-Myc dynamics, and the model includes asymmetric inheritance of c-Myc between daughter cells. A lineage tracking module is also added to follow the descendants and division histories of individual simulated T cell families.
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