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Records Added in June 2020
Records added in June 2020
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Showing records 101 to 125 of 231. [First] Page: 1 2 3 4 5 6 7 8 9 Last
A Novel DC-Coil-Free Hybrid-Excited Machine with Consequent-Pole PM Rotor
Qingsong Wang, Shuangxia Niu
June 23, 2020 (v1)
Subject: Other
Keywords: consequent-pole, DC coil free, hybrid-excited, magnet-iron
This paper proposes a new DC coil free hybrid excited machine concept, which has no external field windings. The technical novelty is the integration of field windings and armature windings. DC bias current is injected into the excitation and the field windings in the traditional hybrid excited machine are eliminated. Compared with traditional hybrid-excited machines with additional field windings, the proposed machine can realize a higher slot utilization ratio, hence achieve a higher torque density and a wider flux adjusting range. Another advantage of the proposed machine is that the voltage drop associated with flux regulation is small due to the small DC resistance, and the torque generating capability at the flux regulating region can be improved accordingly. The rotor is specifically designed with magnet-iron sequences and a consequent-pole, in which the permanent magnet and iron pole are alternatively employed. A bi-directional flux modulating effect can be achieved, which can... [more]
Primary Frequency Response Enhancement for Future Low Inertia Power Systems Using Hybrid Control Technique
Abdulhameed S. Alsharafi, Ahmad H. Besheer, Hassan M. Emara
June 23, 2020 (v1)
Keywords: frequency nadir, inertia control, primary frequency control, wind turbine
Maintaining the stability of a conventional power system during under frequency events is partially dominated by a natural behavior called inertial response. Although a variable speed wind turbine (VSWT) is fundamentally deprived from such behavior, it was shown recently that it can virtually emulate this response, hence increasing its output power given to the grid to sustain the power balance. This paper reviews and analyzes the performance of four primary frequency control structures, and provides comparison between these controllers in terms of security indices. The results reflect the superiority of the inertia emulation controller and the droop control type in low and high wind speed respectively. To enhance the system frequency control response and take any inherent advantage of each controller, this paper proposes two novel controllers based on combination (hybridization) strategy between the four controllers. The results show that the combination between the inertia emulation... [more]
The Effect of a Large Backfill Area on Grounding Grid Performance
Yaguang Tao, Jianchun Wei, Qingquan Li, Yalin Shi, Tongqiao Zhang, Jiwei Zhang, Xiao Liu
June 23, 2020 (v1)
Keywords: agar gel, backfill material, CDEGS (current distribution, electromagnetic fields, ground, and soil structure analysis), ground simulation test, secondary peak of step voltage
The construction of a substation will undoubtedly change the properties of any surrounding native soil. In order to study the influence of backfill material on grounding grid performance and in turn optimize that performance, current distribution, electromagnetic fields, ground, and soil structure analysis (CDEGS) was undertaken to simulate the secondary peak of the step voltage generated by a large backfill soil area. As for the various parameters of the finite soil volume, the influence of the soil length L, the edge gradient tan θ, and the resistivity ρ on the secondary peak of step voltage was researched. Then, a grounding test system was established, the selection process of the protection resistors was clarified, and the usage method of agar gel was improved. The feasibility of simulating backfill material with agar gel was verified, and the influence of resistivity and soil scale on the secondary peak of the step voltage was tested. The results show that the larger the backfill... [more]
A New Hybrid Prediction Method of Ultra-Short-Term Wind Power Forecasting Based on EEMD-PE and LSSVM Optimized by the GSA
Peng Lu, Lin Ye, Bohao Sun, Cihang Zhang, Yongning Zhao, Jingzhu Teng
June 23, 2020 (v1)
Keywords: ensemble empirical mode decomposition-permutation entropy (EEMD-PE), heuristic algorithm, least squares support vector machine (LSSVM), wind power prediction
Wind power time series data always exhibits nonlinear and non-stationary features, making it very difficult to accurately predict. In this paper, a novel hybrid wind power time series prediction model, based on ensemble empirical mode decomposition-permutation entropy (EEMD-PE), the least squares support vector machine model (LSSVM), and gravitational search algorithm (GSA), is proposed to improve accuracy of ultra-short-term wind power forecasting. To process the data, original wind power series were decomposed by EEMD-PE techniques into a number of subsequences with obvious complexity differences. Then, a new heuristic GSA algorithm was utilized to optimize the parameters of the LSSVM. The optimized model was developed for wind power forecasting and improved regression prediction accuracy. The proposed model was validated with practical wind power generation data from the Hebei province, China. A comprehensive error metric analysis was carried out to compare the performance of our me... [more]
Thermogravimetric, Devolatilization Rate, and Differential Scanning Calorimetry Analyses of Biomass of Tropical Plantation Species of Costa Rica Torrefied at Different Temperatures and Times
Johanna Gaitán-Álvarez, Róger Moya, Allen Puente-Urbina, Ana Rodriguez-Zúñiga
June 23, 2020 (v1)
Keywords: cellulose, differential scanning calorimetry, hemicellulose, thermogravimetric analysis, thermostability, torrefaction
We evaluated the thermogravimetric and devolatilization rates of hemicellulose and cellulose, and the calorimetric behavior of the torrefied biomass, of five tropical woody species (Cupressus lusitanica, Dipteryx panamensis, Gmelina arborea, Tectona grandis and Vochysia ferruginea), at three temperatures (TT) and three torrefaction times (tT) using a thermogravimetric analyzer. Through a multivariate analysis of principal components (MAPC), the most appropriate torrefaction conditions for the different types of woody biomass were identified. The thermogravimetric analysis-derivative thermogravimetry (TGA-DTG) analysis showed that a higher percentage of the hemicellulose component of the biomass degrades, followed by cellulose, so that the hemicellulose energy of activation (Ea) was less than that of cellulose. With an increase in TT and tT, the Ea for hemicellulose decreased but increased for cellulose. The calorimetric analyses showed that hemicellulose is the least stable component i... [more]
Design and Numerical Analysis of a Novel Counter-Rotating Self-Adaptable Wave Energy Converter Based on CFD Technology
Chongfei Sun, Zirong Luo, Jianzhong Shang, Zhongyue Lu, Yiming Zhu, Guoheng Wu
June 23, 2020 (v1)
Keywords: computational fluid dynamics (CFD), counter-rotating, performance characteristics, self-adaptive, wave energy converter (WEC)
The lack of an efficient and reliable power supply is currently one of the bottlenecks restricting the practical application of unmanned ocean detectors. Wave energy is the most widely distributed ocean energy, with the obvious advantages of high energy density and predictability. In this paper, a novel wave energy converter (WEC) for power supply of low-power unmanned ocean detectors is proposed, which is a small-scale counter-rotating self-adaptive point absorber-type WEC. The double-layer counter-rotating absorbers can achieve the torque balance of the whole device. Besides, the self-adaptation of the blade to the water flow can maintain a unidirectional continuous rotation of the single-layer absorber. The WEC has several advantages, including small occupied space, simple exchange process and convenient modular integration. It is expected to meet the power demand of low-power ocean detectors. Through modeling and CFD analysis, it was found that the power and efficiency characterist... [more]
GPS Synchronization of Smart Distributed Converters for Microgrid Applications
Tarek A. Youssef, Aboubakr Salem, Moataz Elsied, Augustin Mpanda Mabwe, Mohammad Ali Yousef Abido, Osama A. Mohammed
June 23, 2020 (v1)
Keywords: carrier synchronization, DC/DC boost converter, global positioning system, microgrids
In this paper, a smart distributed DC/DC converter synchronization advanced technique and phase angle optimization algorithm are proposed using to reduce the DC bus overall ripple. A global positioning system-based scheme is used to synchronize the carrier among the distributed converters. The carrier phase angle optimization among the different converters is inspired by Carrier-Sense Multiple Access protocol. The proposed system is simulated and analyzed using Matlab/Simulink program. As a proof of concept of the proposed technique, two case studies have been investigated under equal and unequal load sharing among the distributed generators. The proposed algorithm shows a significant reduction in the DC bus voltage ripple. To prove the concept, a laboratory test-bed has been built and the proposed algorithm has been implemented to validate the theoretical and simulation results. The close agreement between the experimental and simulation results demonstrates the effectiveness and vali... [more]
Theoretical Analysis of Planar Spiral Coils between Two Multilayer Media for Electric Vehicle Wireless Charging
Zhichao Luo, Xuezhe Wei
June 23, 2020 (v1)
Keywords: analytical model, planar spiral coil, wireless power transfer
Square and circular coils are two typical topologies for coupling coils and are applied to wireless charging. However, most of the research on coupling coils is based on the finite element model (FEM), which is a time-consuming process for 3-D structure coils. In this paper, on the basis of Fourier⁻Bessel transformation and Dual Fourier transformation, two theoretical models of square and circular coils between two multilayer media are proposed. With the proposed models, we consider several important parameters such as the size of the coils, thickness, and permeability of each layer. Thus, both the self-inductance and mutual inductance of two planar coils can be calculated without much computational time. Additionally, these theoretical models can help designers figure out the different trends of self-inductance and mutual inductance, which has plenty of benefits for the preliminary pad design. Lastly, a prototype with a size of 600 mm × 600 mm and a 200 mm air gap was built in order t... [more]
Research on the Inductance/Capacitance Switch Model for an LCC-HVDC Converter in an AC/DC Hybrid Grid
Yangyang He, Xiaodong Zheng, Nengling Tai, Junxian Hou, Wentao Huang
June 23, 2020 (v1)
Keywords: electromagnetic transient simulation, inductance/capacitance (L/C) switch model, LCC-HVDC, parameter setting method, steady state process, switching loss, transient response
In order to improve the simulation speed of the AC/DC hybrid grid, the inductance/capacitance (L/C) switch model for line-commutated converter of high-voltage direct current (LCC-HVDC) is presented in this study. The time domain modeling method is used to analyze the circuit of L/C switch model for the six-pulse system in LCC-HVDC in a switching period. A parameter setting method of L/C switch model is proposed considering the transient response, the steady state performance, switching losses and simulation error of the switch. The inductance/capacitance (L/C) switch model for LCC-HVDC has the advantage of keeping the admittance matrix unchanged regardless of the change of switching state, which improves the simulation efficiency. Finally, the validity of the parameter setting method is verified. Compared with the test results of PSCAD/EMTDC, the accuracy of the proposed LCC-HVDC simulation model is proved. The model is suitable for real-time or offline simulation of AC/DC hybrid grid.
Comparison among Methods for Induction Motor Low-Intrusive Efficiency Evaluation Including a New AGT Approach with a Modified Stator Resistance
Camila Paes Salomon, Wilson Cesar Sant’Ana, Germano Lambert-Torres, Luiz Eduardo Borges da Silva, Erik Leandro Bonaldi, Levy Ely de Lacerda de Oliveira
June 23, 2020 (v1)
Keywords: air-gap torque, condition monitoring, efficiency estimation, induction motors, stator resistance
Induction motors consume a great portion of the generated electrical energy. Moreover, most of them work at underloaded conditions, so they have low efficiencies and waste a lot of energy. Because of this, the efficiency estimation of in-service induction motors is a matter of great importance. This efficiency estimation is usually performed through indirect methods, which do not require invasive measurements of torque or speed. One of these methods is the modified Air-Gap Torque (AGT) method, which only requires voltage and current data, the stator resistance value, and the mechanical losses. This paper approaches the computation of a modified stator resistance including the mechanical losses effect to be applied in the AGT method for torque and efficiency estimation of induction motors. Some improvements are proposed in the computation of this resistance by using a direct method, as well as the possibility to estimate this parameter directly from the nameplate data of the induction m... [more]
The Application of Cyber Physical System for Thermal Power Plants: Data-Driven Modeling
Yongping Yang, Xiaoen Li, Zhiping Yang, Qing Wei, Ningling Wang, Ligang Wang
June 23, 2020 (v1)
Keywords: cyber physical system, data mining, online monitoring and control, physical knowledge, thermal power plants
Optimal operation of energy systems plays an important role to enhance their lifetime security and efficiency. The determination of optimal operating strategies requires intelligent utilization of massive data accumulated during operation or prediction. The investigation of these data solely without combining physical models may run the risk that the established relationships between inputs and outputs, the models which reproduce the behavior of the considered system/component in a wide range of boundary conditions, are invalid for certain boundary conditions, which never occur in the database employed. Therefore, combining big data with physical models via cyber physical systems (CPS) is of great importance to derive highly-reliable and -accurate models and becomes more and more popular in practical applications. In this paper, we focus on the description of a systematic method to apply CPS to the performance analysis and decision making of thermal power plants. We proposed a general... [more]
Enhancing Astaxanthin Biosynthesis by Rhodosporidium toruloides Mutants and Optimization of Medium Compositions Using Response Surface Methodology
Tuyet Nhung Tran, Dai-Hung Ngo, Quoc Tuan Tran, Hoang Chinh Nguyen, Chia-Hung Su, Dai-Nghiep Ngo
June 23, 2020 (v1)
Keywords: astaxanthin accumulation, medium composition, mutant, Optimization, Rhodosporidium toruloides
Astaxanthin is a valuable carotenoid, which has been approved as a food coloring by the US Food and Drug Administration and is considered as a food dye by the European Union (European Commission). This work aimed to attain Rhodosporidium toruloides mutants for enhanced astaxanthin accumulation using ultraviolet (UV) and gamma irradiation mutagenesis. Gamma irradiation was shown to be more efficient than UV for producing astaxanthin-overproducer. Among the screened mutants, G17, a gamma-induced mutant, exhibited the highest astaxanthin production, which was significantly higher than that of the wild strain. Response surface methodology was then applied to optimize the medium compositions for maximizing astaxanthin production by the mutant G17. The optimal medium compositions for the cultivation of G17 were determined as a peptone concentration of 19.75 g/L, malt extract concentration of 13.56 g/L, and glucose concentration of 19.92 g/L, with the maximum astaxanthin yield of 3021.34 µg/L... [more]
Formulation and Functional Properties of Whey Protein-Based Tissue Adhesive Using Totarol as an Antimicrobial Agent
Yifan Hou, Xiaonan Zhang, Cuina Wang, Mingruo Guo
June 23, 2020 (v1)
Subject: Biosystems
Keywords: functional properties, tissue adhesive, totarol, whey protein
Tissue adhesives have been widely used in surgical procedures. Compared to traditional surgical sutures, tissue adhesives provide fast bonding experiences and full closure of wounds. However, current tissue adhesives are mostly fossil-based synthetic products. Therefore, it is of great significance to explore the use of natural materials in tissue adhesives. Whey is a low-end byproduct of cheese manufacturing. Whey protein, a group of small globular proteins, can exhibit adhesive properties if their structures are modified by physical or chemical means. The objectives of this study were to investigate the functional and structural properties of whey protein-based tissue adhesive, along with the antibacterial effect of totarol, a natural antimicrobial agent. Whey protein isolate (WPI) solutions (25%−33% protein) were mixed with different levels (0.1%−0.3% w/w) of totarol. The mixtures were analyzed for total plate count and yeast and mold count. The lap-shear bonding strength was tested... [more]
Minimize the Route Length Using Heuristic Method Aided with Simulated Annealing to Reinforce Lean Management Sustainability
Ahmed M. Abed, Samia Elattar
June 23, 2020 (v1)
Keywords: handling, heuristic methods, simulated annealing, transportation cost minimization
Cost reduction is a cornerstone of the Lean administration’s sustainability through modify its algorithms scheme to become multi-useful. This paper focuses on control “movement” waste, to minimize pipeline, cabling and sewerage network deployments time, to avoid demurrages (i.e., constructor sectors) and quickens planning through two stages. The first belongs to the build constrained hybridization of published heuristic routing methods (e.g., S-Shape, Mid-point, Largest-Gap, Return, Ascending, FLA-5, FLA-6 [Flow Line Analysis], and Composite) to select the shortest path that serves many locations (i.e., Plan-A), while allowing for the modification of these locations during service (i.e., Plan-B). The new locations are grouped into two clusters, the first of which lay on the shortest preferred path, while the second cluster contains locations that do not lay on the preferred path and are therefore moved on the backlogs-list, then use Simulated Annealing when to serve them. Finally, the... [more]
The Integration of Collaborative Robot Systems and Their Environmental Impacts
Lucian Stefanita Grigore, Iustin Priescu, Daniela Joita, Ionica Oncioiu
June 23, 2020 (v1)
Keywords: autonomous robot, continuous execution, integrated solution, mobility, Planning, programming
Today, industrial robots are used in dangerous environments in all sectors, including the sustainable energy sector. Sensors and processors collect and transmit information and data from users as a result of the application of robot control systems and sensory feedback. This paper proposes that the estimation of a collaborative robot system’s performance can be achieved by evaluating the mobility of robots. Scenarios have been determined in which an autonomous system has been used for intervention in crisis situations due to fire. The experimental model consists of three autonomous vehicles, two of which are ground vehicles and the other is an aerial vehicle. The conclusion of the research described in this paper highlights the fact that the integration of robotic systems made up of autonomous vehicles working in unstructured environments is difficult and at present there is no unitary analytical model.
Special Issue on “Microwave Applications in Chemical Engineering”
Huacheng Zhu, Kama Huang, Junwu Tao
June 23, 2020 (v1)
Microwave heating has been widely used in the chemical industry because of its advantages, such as fast heating rate, selective and controllable heating, increasing reaction rate and reducing by-products in chemical reactions. The Special Issue contains research on microwave applications in chemical engineering.
Effect of Bone Morphogenic Protein-2-Loaded Mesoporous Strontium Substitution Calcium Silicate/Recycled Fish Gelatin 3D Cell-Laden Scaffold for Bone Tissue Engineering
Chun-Ta Yu, Fu-Ming Wang, Yen-Ting Liu, Hooi Yee Ng, Yi-Rong Jhong, Chih-Hung Hung, Yi-Wen Chen
June 23, 2020 (v1)
Subject: Biosystems
Keywords: bioprinting, bone morphogenetic protein, bone regeneration, cell-laden scaffold, mesoporous material, recycling material, strontium-doped calcium silicate
Bone has a complex hierarchical structure with the capability of self-regeneration. In the case of critical-sized defects, the regeneration capabilities of normal bones are severely impaired, thus causing non-union healing of bones. Therefore, bone tissue engineering has since emerged to solve problems relating to critical-sized bone defects. Amongst the many biomaterials available on the market, calcium silicate-based (CS) cements have garnered huge interest due to their versatility and good bioactivity. In the recent decade, scientists have attempted to modify or functionalize CS cement in order to enhance the bioactivity of CS. Reports have been made that the addition of mesoporous nanoparticles onto scaffolds could enhance the bone regenerative capabilities of scaffolds. For this study, the main objective was to reuse gelatin from fish wastes and use it to combine with bone morphogenetic protein (BMP)-2 and Sr-doped CS scaffolds to create a novel BMP-2-loaded, hydrogel-based mesopo... [more]
Optimisation and Modelling of Anaerobic Digestion of Whiskey Distillery/Brewery Wastes after Combined Chemical and Mechanical Pre-Treatment
Burcu Gunes, Maxime Carrié, Khaled Benyounis, Joseph Stokes, Paul Davis, Cathal Connolly, Jenny Lawler
June 23, 2020 (v1)
Keywords: anaerobic digestion, lignocellulose, pot ale, pre-treatment, response surface methodology, spent grain
Whiskey distillery waste streams consisting of pot ale (liquid residue) and spent grain (solid residue) are high strength organic wastes and suitable feedstock for anaerobic digestion (AD) from both economic and environmental stand points. Anaerobic digestion of pot ale and pot ale/spent grain mixtures (with mixing ratios of 1:1, 1:3, and 1:5 by wet weight) was performed after implementation of a novel hybrid pre-treatment (combined chemical and mechanical) in order to modify lignocellulosic structure and ultimately enhance digestion yield. Lignin, hemicellulose, and cellulose fractions were determined before and after chemical pre-treatment. Effects of different inoculum rates (10−30−50% on wet basis) and beating times (0−7.5−15 min) on anaerobic digestion of pot ale alone and of pot ale/spent grain mixtures were investigated in lab scale batch mode with a major focus of optimising biogas yield by using response surface methodology (RSM) in Design Expert Software. The highest biogas y... [more]
Investigations on Ozone-Based and UV/US-Assisted Synergistic Digestion Methods for the Determination of Total Dissolved Nitrogen in Waters
Xiaofang Sun, Huixuan Chen, Zhengyu Liu, Mengfei Zhou, Yijun Cai, Haitian Pan, Luyue Xia
June 23, 2020 (v1)
Subject: Other
Keywords: digestion efficiency, digestion method, intensification, ozone, total dissolved nitrogen
Over the past two decades, the alkaline persulfate oxidation (PO) with thermal and/or ultraviolet (UV) assisted digestion method has been widely used for digestion of nitrogen containing compounds (N-compounds) in water quality routine analysis in laboratory or on-line analysis, due to its simple principle, high conversion rate, high percent recovery, low-cost. However, this digestion method still has some inevitable problems such as complex operations, high contamination potential, batch N blanks, higher reaction temperature (120−124 °C) and time-consuming (30−60 min). In this study, ozone (O3) was selected as the oxidant for digestion of N-compounds through analysis and comparison firstly. Secondly, we proposed and compared the UV and/or ultrasound (US) combined with ozone (UV/O3, US/O3 and UV/US/O3) synergistic digestion methods based on O3 with sole O3 oxidation method on digestion efficiency (digestion time and conversion rate) of standard N-compounds. Simultaneously, the influenc... [more]
Thermal and Torrefaction Characteristics of a Small-Scale Rotating Drum Reactor
Nitipong Soponpongpipat, Suwat Nanetoe, Paisan Comsawang
June 23, 2020 (v1)
Keywords: energy yield, heat loss, heating rate, mass yield, rotating drum reactor, torrefaction
The small-scale rotating drum reactor (SS-RDR) was designed and constructed without using purge gas for the purpose of household application. The thermal and torrefaction characteristics of SS-RDR were studied and compared with other reactor types. It was found that the heat loss at the reactor wall and heat loss from exhaust gas of the SS-RDR were in the range of 6.3−12.4% and 27.9−42.8%, respectively. The increase of flue gas temperature resulted in the decrease of heat loss at the reactor wall and the increase of heat loss from exhaust gas. The heating rate of the SS-RDR was in the range of 7.3−21.4 °C/min. The higher heating value (HHV) ratio, mass yield, and energy yield ofthe SS-RDR were in the range of 1.2−1.6, 35.0−81.0%, and 56.2−96.5%, respectively. A comparison of torrefaction characteristics of various reactor types on HHV ratio-mass yield-iso-energy yield diagram indicated that the torrefaction characteristics of the SS-RDR were better than that of the rotating drum reacto... [more]
Mesoporous Mn-Doped Fe Nanoparticle-Modified Reduced Graphene Oxide for Ethyl Violet Elimination: Modeling and Optimization Using Artificial Intelligence
Yu Hou, Jimei Qi, Jiwei Hu, Yiqiu Xiang, Ling Xin, Xionghui Wei
June 23, 2020 (v1)
Subject: Materials
Keywords: Artificial Intelligence, ethyl violet, gradient boosted regression trees, mesoporous materials, Mn-doped Fe/rGO nanocomposites
Mesoporous Mn-doped Fe nanoparticle-modified reduced graphene oxide (Mn-doped Fe/rGO) was prepared through a one-step co-precipitation method, which was then used to eliminate ethyl violet (EV) in wastewater. The prepared Mn-doped Fe/rGO was characterized by X-ray diffraction, X-ray photoelectron spectroscopy, Raman spectroscopy, high-resolution transmission electron microscopy, scanning electron microscopy, energy dispersive spectroscopy, N2-sorption, small angle X-ray diffraction and superconducting quantum interference device. The Brunauer−Emmett−Teller specific surface area of Mn-doped Fe/rGO composites was 104.088 m2/g. The EV elimination by Mn-doped Fe/rGO was modeled and optimized by artificial intelligence (AI) models (i.e., radial basis function network, random forest, artificial neural network genetic algorithm (ANN-GA) and particle swarm optimization). Among these AI models, ANN-GA is considered as the best model for predicting the removal efficiency of EV by Mn-doped Fe/rGO... [more]
Hydroxyapatite Biosynthesis Obtained from Sea Urchin Spines (Strongylocentrotus purpuratus): Effect of Synthesis Temperature
Nayeli Sarahi Gómez Vázquez, Priscy Alfredo Luque Morales, Claudia Mariana Gomez Gutierrez, Osvaldo de Jesus Nava Olivas, Ruben Cesar Villarreal Sánchez, Alfredo Rafael Vilchis Nestor, Manuel de Jesús Chinchillas Chinchillas
June 23, 2020 (v1)
Subject: Other
Keywords: biomaterial, hydroxyapatite, sea urchin, Strongylocentrotus purpuratus
In this investigation, hydroxyapatite (HA) was synthesized using sea urchin spines (Strongylocentrotus purpuratus) via a precipitation and heat treatment method at three different temperatures (500, 600 and 700 °C). Biosynthesized HA was characterized to determine the vibration of functional groups, morphology, particle size, crystalline structure and chemical composition. For this, Fourier-Transform Infrared Spectroscopy with Attenuated Total Reflectance (FTIR-ATR), Scanning Electron Microscopy (SEM) coupled with Energy Dispersive X-ray Spectroscopy (EDS), X-ray Diffraction (XRD) and X-ray Photoelectron Spectroscopy (XPS) were used, respectively. The FTIR-ATR results reveal that the most defined characteristic HA bonds (O-H, P-O and C-O bonds) were better defined at higher synthesis temperatures. SEM also presented evidence that temperature has a significant effect on morphology. EDS results showed that the Ca/P ratio increased in the samples at higher temperatures. XRD analysis prese... [more]
Holographic Imaging of Insect Cell Cultures: Online Non-Invasive Monitoring of Adeno-Associated Virus Production and Cell Concentration
Daniel A. M. Pais, Paulo R. S. Galrão, Anastasiya Kryzhanska, Jérémie Barbau, Inês A. Isidro, Paula M. Alves
June 23, 2020 (v1)
Subject: Biosystems
Keywords: AAV-adeno-associated virus, cell culture monitoring, digital holographic microscopy, insect cell-baculovirus, process analytical technology
The insect cell-baculovirus vector system has become one of the favorite platforms for the expression of viral vectors for vaccination and gene therapy purposes. As it is a lytic system, it is essential to balance maximum recombinant product expression with harvest time, minimizing product exposure to detrimental proteases. With this purpose, new bioprocess monitoring solutions are needed to accurately estimate culture progression. Herein, we used online digital holographic microscopy (DHM) to monitor bioreactor cultures of Sf9 insect cells. Batches of baculovirus-infected Sf9 cells producing recombinant adeno-associated virus (AAV) and non-infected cells were used to evaluate DHM prediction capabilities for viable cell concentration, culture viability and AAV titer. Over 30 cell-related optical attributes were quantified using DHM, followed by a forward stepwise regression to select the most significant (p < 0.05) parameters for each variable. We then applied multiple linear regres... [more]
Computational Approaches for Studying Slag−Matte Interactions in the Flash Smelting Furnace (FSF) Settler
Jani-Petteri Jylhä, Nadir Ali Khan, Ari Jokilaakso
June 23, 2020 (v1)
Keywords: CFD–DEM, coalescence, Computational Fluid Dynamics, funneling flow, settling
Computational methods have become reliable tools in many disciplines for research and industrial design. There are, however, an ever-increasing number of details waiting to be included in the models and software, including, e.g., chemical reactions and many physical phenomena, such as particle and droplet behavior and their interactions. The dominant method for copper production, flash smelting, has been extensively investigated, but the settler part of the furnace containing molten high temperature melts termed slag and matte, still lacks a computational modeling tool. In this paper, two commercial modeling software programs have been used for simulating slag−matte interactions in the settler, the target being first to develop a robust computational fluid dynamics (CFD) model and, second, to apply a new approach for molten droplet behavior in a continuum. The latter is based on CFD coupled with the discrete element method (DEM), which was originally developed for modeling solid partic... [more]
Short-Term Load Forecasting Using Smart Meter Data: A Generalization Analysis
Aida Mehdipour Pirbazari, Mina Farmanbar, Antorweep Chakravorty, Chunming Rong
June 23, 2020 (v1)
Keywords: deep learning, generalization analysis, Machine Learning, short-term load forecasting, smart meters
Short-term load forecasting ensures the efficient operation of power systems besides affording continuous power supply for energy consumers. Smart meters that are capable of providing detailed information on buildings energy consumption, open several doors of opportunity to short-term load forecasting at the individual building level. In the current paper, four machine learning methods have been employed to forecast the daily peak and hourly energy consumption of domestic buildings. The utilized models depend merely on buildings historical energy consumption and are evaluated on the profiles that were not previously trained on. It is evident that developing data-driven models lacking external information such as weather and building data are of great importance under the situations that the access to such information is limited or the computational procedures are costly. Moreover, the performance evaluation of the models on separated house profiles determines their generalization abili... [more]
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