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Showing records 2137 to 2161 of 43292. [First] Page: 1 83 84 85 86 87 88 89 90 91 Last
Effects of Layering Angle and Prestress on Dynamic Load Energy Conversion and Damage Mechanism of Sandstone
Wenbing Fan, Junwen Zhang, Yang Yang, Kailun Fang, Shaokang Wu, Yulong Xing
January 12, 2024 (v1)
Keywords: damage mechanism, failure mechanism, internal energy conversion, layered sandstone, mining application, phased energy characteristics
Previously conducted studies have established the conversion relationship between incident energy, reflected energy, transmitted energy and absorbed energy of rocks under dynamic load. In this paper, the combined dynamic and static loading tests of sandstone under different prestress and different bedding angles are carried out to explore the law of the influence of prestress and bedding angles on energy evolution and damage evolution. The purpose is to provide some reference for deep mining, rock engineering design and geological hazard assessment. The energy conversion and damage characteristics of sandstone in the whole process of deformation are studied, and the internal energy conversion mechanism of sandstone under dynamic load is proposed. It is found that the increase in prestress will lead to the increase in the initial energy value of sandstone and further affect the shape of the energy evolution curve. In addition, the relationship between strain and energy transformation is... [more]
Investigation of the Adsorption Process of Triclosan from an Aqueous Solution, Using Nanoporous Carbon Adsorbents, Obtained after Treatment of Organic Household and Vegetable Waste
Ivanka Stoycheva, Bilyana Petrova, Boyko Tsyntsarski, Pavlina Dolashka, Angelina Kosateva, Nartzislav Petrov
January 12, 2024 (v1)
Subject: Environment
Keywords: Adsorption, environmental protection, nanoporous carbon adsorbents, organic waste, triclosan
The absorption of triclosan on the surface of four different carbon adsorbents, obtained on the base of plant and household waste (RDF), provided by Sofia Waste Plant, was investigated. The obtained results indicate that the most important parameters, which determine the process of triclosan adsorption by adsorbent surface are pore texture, the size of the accessible surface for the molecules of triclosan, and the chemical nature of the adsorbent surface. It was found that the obtained adsorbents can be successfully applied for the extraction of triclosan from waste and drinking water. The possibilities for solid products, obtained by thermal treatment of household and vegetable waste, to be applied successfully in a water purification technique are discussed.
Geological Features, Paleosedimentary Environment, and Organic Matter Accumulation Mechanisms of the Lacustrine Shale Oil System: A Case Study of the Jurassic Dongyuemiao Member in the Sichuan Basin
Enze Wang, Yang Li, Tonglou Guo, Liang Xiong, Xiaoxia Dong, Tong Wang, Kaibo Shi
January 12, 2024 (v1)
Subject: Environment
Keywords: Dongyuemiao member, lacustrine shale, organic matter accumulation mechanism, sedimentary environment
Lacustrine shale has garnered significant attention due to its significant resource potential. The Jurassic shale in the Sichuan Basin is an important target for lacustrine shale exploration in China. However, previous studies have predominantly focused on the Da’anzhai member of the Ziliujing Formation, and little attention has been paid to the shale of other strata. This paper aims to address this gap by investigating the Jurassic Dongyuemiao member in the Sichuan Basin. The study systematically characterizes the geological properties of the Dongyuemiao shale system, reconstructs the paleosedimentary environment, identifies the key factors influencing organic matter (OM) enrichment and physical properties, and assesses its resource potential through comparative analysis. Our results show that the Dongyuemiao shale was deposited in an oxic and semi-humid sedimentary environment characterized by intense weathering conditions. The enrichment of OM in the shale is primarily controlled by... [more]
Process Optimization of Sea Buckthorn Fruit Powder Effervescent Tablets by Random Centroid Methodology Combined with Fuzzy Mathematical Sensory Evaluation
Yan Ma, Yali Lian, Xintao Meng, Mingqiang Xu, Ting Zhang, Hui Zou, Haiyan Yang
January 12, 2024 (v1)
Subject: Optimization
Keywords: effervescent tablet, random centroid methodology, sea buckthorn fruit powder, sensory evaluation
Solid beverages of effervescent tablets have good taste and portable features and are favored by consumers, but product quality and nutrition cannot meet the need of increasing nutritional requirements. Sea buckthorn fruit has a special flavor and nutrient-rich characteristics, but the related products of effervescent tablets have not been developed. In this paper, different additive contents (sea buckthorn fruit powder, erythritol, disintegrant, maltodextrin, polyvinylpyrrolidone (PVP)) were optimized using the random centroid method; the obtained effervescent effect sensory evaluation characteristics (appearance, beverage, appearance, taste, solubility) were used to establish a fuzzy mathematic model for sensory evaluation method of process optimizing; and the nutritional components and characteristics of optimized sea buckthorn powder effervescent tablets were compared to the ones of the commercial product. The results show that the optimal process conditions (47.7% sea buckthorn fr... [more]
Static and Fatigue Characterization of Adhesive T-Joints Involving Different Adherends
Georgino C. G. Serra, José A. M. Ferreira, Paulo N. B. Reis
January 12, 2024 (v1)
Subject: Materials
Keywords: damage mechanisms, fatigue strength, mechanical testing, static characterization, structural adhesives, T-joints
It is very important to understand the damage mechanisms as well as the mechanical response of T-joints involving different materials on the base plate. For this purpose, two configurations were studied. In one, the joint is composed of a base plate and a T-element, both in Al 6063-T5, while in the other one, the aluminum base plate was replaced by a glass fiber composite. Finally, each configuration was divided into two batches, where in one, the elements were bonded with a stiff adhesive (Araldite® AV 4076-1/HY 4076) while in the other, a more ductile adhesive (Araldite® AW 106/HV 953 U) was used. The static and fatigue strength of all configurations was evaluated in bending. In all cases, the damage occurred at the end of the T-element, where a crack appeared and propagated toward the interior of the T-joint. The bending strength is highest for joints involving aluminum and the ductile adhesive, which is 2.8 times higher than the same configuration involving composite base plates an... [more]
Modeling of Continuous Slug Flow Cooling Crystallization towards Pharmaceutical Applications
Anne Cathrine Kufner, Michael Rix, Kerstin Wohlgemuth
January 12, 2024 (v1)
Keywords: active pharmaceutical ingredients, continuous crystallization, high-quality products, mechanistic modeling, slug flow crystallizer
The rising trend towards continuous production in the field of small-scale crystallization has generated many creative concepts for apparatuses for the production of active pharmaceutical ingredients. One of these promising apparatuses is the Slug Flow Crystallizer (SFC), which enables the adjustment of the particle size distribution and the achievement of high yields through its alternating slug flow. To realize and understand the crystallization inside the SFC, high experimental effort has been necessary until now. Therefore, a mechanistic model considering the hydrodynamics of slug flow, the energy and mass balances, and the crystallization phenomena of growth and agglomeration inside the apparatus was developed. Its purpose is to improve the understanding of the process, estimate the effects of operating parameters on target properties, and predict crystallization behavior for different substance systems with minimal experimental effort. Successful modeling was validated with exper... [more]
Study on Brittleness Characteristics and Fracturing Crack Propagation Law of Deep Thin-Layer Tight Sandstone in Longdong, Changqing
Changjing Zhou, Zhonghua Sun, Yuanxiang Xiao, Guopeng Huang, Dan Kuang, Minghui Li
January 12, 2024 (v1)
Keywords: brittleness characteristics, fracture propagation, hydraulic fracturing, tight sandstone, triaxial compression
Tight-sandstone oil and gas resources are the key areas of unconventional oil and gas resources exploration and development. Because tight-sandstone reservoirs usually have the characteristics of a low porosity and ultralow permeability, large-scale hydraulic fracturing is often required to form artificial fractures with a high conductivity to achieve efficient development. The brittleness of rock is the key mechanical factor for whether fracturing can form a complex fracture network. Previous scholars have carried out a lot of research on the brittleness characteristics of conglomerate and shale reservoirs, but there are few studies on the brittleness characteristics of sandstone with different types and different coring angles in tight-sandstone reservoirs and the fracture propagation law of sandstone with different brittleness characteristics. Based on this, this paper carried out a systematic triaxial compression and hydraulic fracturing experiment on the tight sandstone of Shan 1... [more]
Synergistic Catalysis of Reservoir Minerals and Exogenous Catalysts on Aquathermolysis of Heavy Oil
Yunlei Zang, Huaizhu Liu, Dong Chen, Shu Zhang, Shanjian Li, Gang Chen
January 12, 2024 (v1)
Subject: Materials
Keywords: catalytic aquathermolysis, heavy oil, reservoir minerals, synergistic
In this study, based on existing heavy oil extraction technology, combined with the mineral composition in a reservoir, the synergistic catalytic effect of reservoir minerals and exogenous catalysts under the reaction system of a hydrogen-rich environment not only reduces the viscosity of thick oil but also reduces the extraction cost and further improves the recovery rate of heavy oil. In this study, the impacts of different reservoir minerals and exogenous catalysts on the aquathermolysis of heavy oil were investigated. The research results showed that the sodium montmorillonite within the reservoir minerals exhibited an optimal catalytic effect, and the synergistic catalytic effect of sodium montmorillonite and catalyst C-Fe (catechol iron) resulted in a viscosity reduction rate of 60.47%. Furthermore, the efficiency of different alcohols as hydrogen donors was screened, among which ethanol had the best catalytic effect. Under the optimal reaction conditions, the viscosity reduction... [more]
An Improved Dual Second-Order Generalized Integrator Phased-Locked Loop Strategy for an Inverter of Flexible High-Voltage Direct Current Transmission Systems under Nonideal Grid Conditions
Lai Peng, Zhichao Fu, Tao Xiao, Yang Qian, Wei Zhao, Cheng Zhang
January 12, 2024 (v1)
Keywords: DC bias, flexible DC transmission, harmonic voltage, PLL, power quality, unbalance voltage
High-voltage flexible power systems, with their intrinsic characteristics, play an increasingly important role in electronic power systems. Synchronization between the inverter and the grid needs to be achieved by a phase-locked loop (PLL), the performance of which determines the quality of power transmission. This paper proposes a PLL adapted to extremely harsh grid conditions. Firstly, the traditional synchronous reference frame PLL and the dual second-order generalized integrator (DSOGI-PLL) are analyzed, and the errors in phase-locking and the shortcomings of these two methods in the presence of DC components in the grid are pointed out. Secondly, based on the harmonic grid voltage, a repetitive control internal model is introduced by DSOGI to realize the real-time tracking and regulation of the harmonic signals in order to suppress the harmonic voltage disturbance. In addition, a DC bias elimination and frequency adaptive method is proposed to solve the problems of DC bias and gri... [more]
Comprehensive Evaluation Index System and Application of Low-Carbon Resilience of Power Grid Containing Phase-Shifting Transformer under Ice Disaster
Jing Zhang, Huilin Cheng, Peng Yang, Bingyan Zhang, Shiqi Zhang, Zhigang Lu
January 12, 2024 (v1)
Keywords: fuzzy comprehensive evaluation, ice disaster, low-carbon resilience indicators, phase-shifting transformer
In view of the high impact of extreme disasters, this paper comprehensively evaluates power grid performance from a new low-carbon toughness perspective. First, considering the increase in carbon emissions and the recovery time of carbon emissions, low-carbon resilience indicators are proposed. At the same time, considering the power-regulation effect of the phase-shifter transformer, the fault and response model of a power grid under an ice disaster is established, and then, a comprehensive evaluation index system of low-carbon toughness of the power grid is constructed. The weight determination is carried out using the fuzzy analytic hierarchy process-entropy-based weight method, while the fuzzy comprehensive evaluation center of gravity method is used to evaluate the power grid comprehensively. Finally, examples are presented to verify the feasibility of the proposed method, emphasizing its potential for evaluating the comprehensive performance of low-carbon and toughness of the pow... [more]
Energy-Saving Testing System for a Coal Mine Emulsion Pump Using the Pressure Differential Flow Characteristics of Digital Relief Valves
Jie Tian, Wenchao Liu, Hongyao Wang, Xiaoming Yuan, Rulin Zhou, Junshi Li
January 12, 2024 (v1)
Keywords: digital relief valve, emulsion pump, energy saving testing, flow control, water-based hydraulic system
Most energy-saving testing methods for plunger pumps use hydraulic motors. The loading test of coal mine emulsion pumps generally uses an overflow valve as the loading unit, which is characterized by high energy consumption. The coal mine emulsion pump uses emulsion as the transmission medium, and the viscosity and lubricity of the emulsion are much lower than those of hydraulic oil, which creates great difficulties in the development of high water-based hydraulic products. The nominal flow rate of the emulsion motor is much smaller than that of the emulsion pump, and there is no mature and reliable water-based flow control valve. Based on the above reasons, traditional energy-saving testing methods cannot be utilized for the testing process of emulsion pumps. The loading test of emulsion pumps generally uses an overflow valve as the loading unit, and during the testing process, all electrical energy is converted into internal energy, resulting in very high energy consumption. This art... [more]
Cu2O-Electrodeposited TiO2 Photoelectrode for Integrated Solar Redox Flow Battery
Zihan Zhang, Ping Lu, Zixing Gu, Qiang Ma, Zhizhong Guo, Huaneng Su, Qian Xu
January 12, 2024 (v1)
Keywords: Cu2O, electrodeposition, integrated solar redox flow battery, photoelectrode, TiO2
TiO2 photoelectrode has become an attractive platform due to its excellent photoelectric performance and has been widely used in battery, photocatalysis, and other photoelectric fields. However, when the TiO2 photoelectrode is used in solar flow batteries, the small photo-charging current is a potential problem, which will extend the charging process and lower the battery utilization efficiency. To address this issue, Cu2O is introduced to the surface of the TiO2 photoelectrode, and Cu2O-TiO2 forms a heterojunction to improve battery performance in this work. The formation mechanism of Cu2O-TiO2 is revealed and utilized to deposit Cu2O on pre-treated FTO glass covered with TiO2 films using electrochemical deposition (ECD). The photoelectrochemical properties of Cu2O-TiO2 photoelectrodes are characterized using XRD, UV-vis diffuse reflectance spectroscopy, XPS, and electrochemical characterizations. The successful deposition of Cu2O on the surface of TiO2 photoelectrode is confirmed, an... [more]
Judgment Basis and Mechanical Analysis of Current Collector Failure in the Winding Process of a Lithium-Ion Battery
Yuxin Zhang, Chunhui Zhao, Xiaozhong Du, Jianjun Zhao, Yijian Hu
January 12, 2024 (v1)
Keywords: circumferential strain, current collector, failure criterion, lithium-ion battery, mechanical property
The winding process is one of the essential processes in the manufacturing of lithium-ion batteries (LIBs). Current collector failure frequently occurs in the winding process, which severely increases the production cost and reduces production efficiency. In order to solve this problem, we first analyze the relationship between different process parameters and the failure of the current collector, and put forward the standard to determine the failure of the current collector. Moreover, we conducted tensile experiments to validate the differences in the mechanical performance of the current collector under different thicknesses. Finally, the circumferential stress and strain of the current collector winding were calculated using finite element analysis. The accuracy of the proposed criterion for determining current collector failure was verified through experimental measurements of stress and strain. The results demonstrate that the criterion proposed in this study can accurately calcul... [more]
Three-Dimensional Printing Technologies in Oral Films Manufacturing—A Minireview
Emma Adriana Ozon, Iulian Sarbu, Violeta Popovici, Mirela Adriana Mitu, Adina Magdalena Musuc, Oana Karampelas, Bruno Stefan Velescu
January 12, 2024 (v1)
Subject: Biosystems
Keywords: 3D inkjet printing, active pharmaceutical ingredients, buccal drug delivery, extrusion-based 3D printing methods, liquid crystal display 3D printing, oral films, personalized medicine, Polymers
The interest in buccal drug delivery is under consideration due to some distinct properties compared to the traditional pharmaceutical formulations for oral administration: significantly higher bioavailability, a faster absorption rate of the drug, and substantial compliance for special needs patients. Oral films are obtained through various technologies, from conventional tools to 3D and 4D printing approaches. This minireview aims to describe the current additive manufacturing technologies in oral film fabrication, display their advantages and limitations, and discuss various formulation strategies. It also provides advanced data regarding synthetic and natural polymers used in 3D printing technologies for oral films. Moreover, it shows the most recent studies with 3D-printed orodispersible films and mucoadhesive buccal films manufactured through previously analyzed methods. Finally, conclusions and future perspectives are also briefly summarized.
The Analysis of Hydraulic Fracture Morphology and Connectivity under the Effect of Well Interference and Natural Fracture in Shale Reservoirs
Shuangming Li, Huan Zhao, Tian Cheng, Jia Wang, Jingming Gai, Linhao Zou, Tiansu He
January 12, 2024 (v1)
Keywords: fracture connectivity, fracture morphology, horizontal well, natural fracture, well interference
Employing multi-stage fracturing technology in horizontally accessed wells is a well-known way to successfully develop shale reservoirs. The interaction between natural fractures and hydraulic fractures has a significant impact on the fracturing effect. In this study, a coupled model of rock deformation and fluid flow was established using the cohesive zone method to simulate the propagation of hydraulic fractures under the synergistic effect of natural fractures and wellbore interference. The influence of in situ stress, fracture spacing, the number of fracture clusters, and the fracturing methods on the formation of fracture networks was analyzed. Studies on the fracture morphology and connectivity of fracture networks show that when the in situ stress difference is small, multiple fractures can easily form, and when the in situ stress difference is large, they can easily gather into a single fracture. An excessive reduction in fracture spacing may impede the optimal propagation and... [more]
Study of the Optimization of Rail Pressure Characteristics in the High-Pressure Common Rail Injection System for Diesel Engines Based on the Response Surface Methodology
Ruichuan Li, Wentao Yuan, Jikang Xu, Lin Wang, Feng Chi, Yong Wang, Shuqiang Liu, Jianghai Lin, Qingguang Zhang, Lanzheng Chen
January 12, 2024 (v1)
Keywords: average rail pressure, average rail pressure fluctuation, diesel engines, high-pressure common rail, response surface methodology
This paper establishes a mathematical model of the high-pressure common rail injection system used in diesel engines according to the parameters of its key components, and AMESim 2020 software was used to establish a simulation model of the common rail injection system used in diesel engines. The simulation model mainly includes a high-pressure oil pump model, a common rail pipe model, and a model of four injectors. This paper also describes an experimental analysis of the accuracy of the established simulation model. Through a simulation analysis of the system rail’s pressure fluctuation and pressure characteristics, it was concluded that the length of the common rail pipe, the diameter of the common rail pipe, and the inner diameter of the high-pressure fuel pipes are important influencing parameters for the rail pressure characteristics of the system. In this study, according to the original common rail pipe and high-pressure fuel pipe model, a response surface methodology was used... [more]
Design, Multi-Perspective Computational Investigations, and Experimental Correlational Studies on Conventional and Advanced Design Profile Modified Hybrid Wells Turbines Patched with Piezoelectric Vibrational Energy Harvester Devices for Coastal Regions
Janani Thangaraj, Senthil Kumar Madasamy, Parvathy Rajendran, Safiah Zulkifli, Rajkumar Rajapandi, Hussein A. Z. AL-bonsrulah, Beena Stanislaus Arputharaj, Hari Prasath Jeyaraj, Vijayanandh Raja
January 12, 2024 (v1)
Keywords: composite materials, Computational Fluid Dynamics, FEA, forced and free vibrations, FSI, hybrid energy, hydro-energy
This work primarily investigates the performance and structural integrity of the Wells turbines for power production in coastal locations and their associated unmanned vehicles. An innovative design procedure is imposed on the design stage of the Wells turbine and thus so seven different models are generated. In the first comprehensive investigation, these seven models underwent computational hydrodynamic analysis using ANSYS Fluent 17.2 for various coastal working environments such as hydro-fluid speeds of 0.34 m/s, 1.54 m/s, 12 m/s, and 23 m/s. After this primary investigation, the best-performing Wells turbine model has been imposed as the second comprehensive computational investigation for three unique design profiles. The imposed unique design profile is capable of enhancing the hydro-power by 15.19%. Two detailed, comprehensive investigations suggest the best Wells turbine for coastal location-based applications. Since the working environments are complicated, additional advance... [more]
Molecular Dynamics Calculation of the Coordination Behavior of Yb (III) in Sodium Carbonate Solution
Qiaofa Lan, Youming Yang, Ziyu Xie, Haoran Guo, Donghui Liu, Xiaolin Zhang
January 12, 2024 (v1)
Subject: Materials
Keywords: carbonate, coordination, density functional theory, molecular dynamics, Yb (III)
Yb (III) shows complex behavior of coordination dissolution and precipitation in carbonate solutions, but the properties of CO32− coordination and hydration to Yb (III) in the solution have not been explicated. In this work, the dissolution rule of Yb (III) with CO32− concentration has been studied. The radial distribution function and the coordination number of CO32− and H2O to Yb (III) were calculated by molecular dynamics simulation, and the complex ion form of Yb was obtained. The ultraviolet−visible spectrum and the ionic structures of Yb (III) complex ions were geometrically optimized and calculated by using density functional theory. Then, the experimental ultraviolet−visible spectra and density functional theory results were combined to verify the molecular dynamics calculations. The results indicate that Yb (III) undergoes precipitation in low-concentration carbonate solution, but, in high-concentration carbonate solution, Yb (III)’s carbonates will undergo dissolution. The ma... [more]
Unraveling Oxygen Transfer Behavior in Submerged Arc Welding Using CaF2-SiO2-CaO Fluxes
Jin Zhang, Jun Fan, Dan Zhang
January 12, 2024 (v1)
Keywords: flux, multi-zone model, oxygen content, oxygen transfer, submerged arc welding (SAW), thermodynamic equilibrium, weld metal composition, welding metallurgy
The purpose of this study is to investigate the transfer behavior of oxygen during the submerged arc welding process using CaF2-SiO2-CaO fluxes. In contrast to previous research that only focused on the final oxygen content in the final weld metal, this study introduces two new parameters, ΔdO and ΔwO, to quantify the oxygen transfer in essential regions: the droplet and weld pool zones, respectively. The transfer behavior of oxygen is analyzed by using typical Multi-Zone and equilibrium models. The results indicate that the Multi-Zone model is capable of capturing the metallurgical processes of oxidation and subsequent reduction during the submerged arc welding process. Moreover, the Multi-Zone model demonstrates superior predictive accuracy in estimating oxygen content in the metal compared to the equilibrium model. Based on measured values and metallurgical data, this article analyzes the oxygen transfer mechanism and non-equilibrium state in the submerged arc welding process from b... [more]
Multi-Objective Optimization of Kinetic Characteristics for the LBPRM-EHSPCS System
Yuhang Zhang, Gexin Chen, Guishan Yan, Boyuan Li, Jianxin Lu, Wenguang Jiang
January 12, 2024 (v1)
Keywords: dynamic characteristics, economic characteristics, efficiency characteristics, electro-hydraulic servo pump control system (EHSPCS), lithium-ion battery pole rolling mill (LBPRM), NSGA-II, optimum design
As the ‘heart’ of energy vehicles, the lithium-ion battery is in desperate need of precision improvement, green production, and cost reduction. To achieve this goal, the electro-hydraulic servo pump control system (EHSPCS) is applied to the lithium-ion battery pole rolling mill (LBPRM). However, this development can lead to limited dynamic performance and large power loss as a result of the EHSPCS unique volume direct-drive control mode. At present, how to solve this conflict has not been studied and how the EHSPCS component parameters influence the dynamic response, power loss, and economic performance is not clear. In this paper, a multi-objective optimization (MOO) model for the LBPRM-EHSPCS is proposed by comprehensively considering the dynamic, efficiency, and economic characteristics. Firstly, the evaluation model of the dynamic response, power loss, and cost is investigated. Then, the NSGA-II algorithm is introduced to address the Pareto front of the MOO model. Finally, the powe... [more]
Axial Force Calculation Model for Completion String with Multiple Point Resistances in Horizontal Well
Zhen Nie, Shuzhe Shi, Bohong Wu, Xueqin Huang
January 12, 2024 (v1)
Keywords: axial force, completion string, hook load, horizontal well, local resistance
Frequent accidents may happen during the string run-down and pull process due to the lack of accuracy in the prediction of string force analysis. In order to precisely predict the completion string axial force in horizontal wells, a new model is established, and an in-house software has been developed. The model aims to predict the multiple local resistances that occur at different points on the completion string, which makes up for the technical defects of the commonly used software. It can calculate resistance at different points of the string, which will lead to varying hook load amplification. This method can also predict the axial force of the completion string. By changing the hook load, location, and direction, the resistance can be determined more accurately. Based on the calculation and analysis, the relationship between local resistance, the blocking point, and the amplification factor is also obtained. Furthermore, this model is used to analyze the local resistance of a hori... [more]
Identification of an Antimicrobial Protease from Acanthamoeba via a Novel Zymogram
Alvaro de Obeso Fernández del Valle, Luis Javier Melgoza-Ramírez, María Fernanda Esqueda Hernández, Alfonso David Rios-Pérez, Sutherland K. Maciver
January 12, 2024 (v1)
Keywords: Acanthamoeba, antimicrobial, encystment, protease, zymogram
Proteases play a role in different processes for protozoans and for the free-living amoeba Acanthamoeba. Some of these processes are related to pathogenicity and to encystment. In this study we describe the discovery of a protease with antimicrobial activity produced by Acanthamoeba. To identify it, we developed a novel zymogram using bacteria as an in-gel substrate that can help identify proteins capable of bacterial degradation. We used chromatography to isolate the proteases and showed that it quickly degrades in the environment. Additionally, we identified overexpressed proteases during encystment. The study of proteases from Acanthamoeba can serve several purposes including new antimicrobial proteins that the amoeba can use for potentially predigesting prokaryotes. Secondly, it can help with the identification of potential new therapies against Acanthamoeba infection.
Risk Assessment of Coal Mine Gas Explosion Based on Fault Tree Analysis and Fuzzy Polymorphic Bayesian Network: A Case Study of Wangzhuang Coal Mine
Jinhui Yang, Jin Zhao, Liangshan Shao
January 12, 2024 (v1)
Keywords: coal mine gas explosion, fault tree analysis, fuzzy theory, polymorphic Bayesian network, risk assessment
The prevention and control of gas explosion accidents are important means to improving the level of coal mine safety, and risk assessment has a positive effect on eliminating the risk of gas explosions. Aiming at the shortcomings of current risk assessment methods in dynamic control, state expression and handling uncertainty, this study proposes a method combining fault tree analysis and fuzzy polymorphic Bayesian networks. The risk factors are divided into multiple states, the concept of accuracy is proposed to correct the subjectivity of fuzzy theory and Bayesian networks are relied on to calculate the risk probability and risk distribution in real time and to propose targeted prevention and control measures. The results show that the current risk probability of a gas explosion accident in Wangzhuang coal mine is as high as 35%, and among the risk factors, excessive ventilation resistance and spontaneous combustion of coal are sources of induced risk, and the sensitivity value of ele... [more]
Synthesis of Silver Nanoparticles: From Conventional to ‘Modern’ Methods—A Review
Ngoc Phuong Uyen Nguyen, Ngoc Tung Dang, Linh Doan, Thi Thu Hoai Nguyen
January 12, 2024 (v1)
Subject: Materials
Keywords: AgNPs, biological synthesis, chemical synthesis, physical synthesis, silver nanoparticles
Silver nanoparticles, also known as AgNPs, have been extensively researched due to their one-of-a-kind characteristics, including their optical, antibacterial, and electrical capabilities. In the era of the antibiotics crisis, with an increase in antimicrobial resistance (AMR) and a decrease in newly developed drugs, AgNPs are potential candidates because of their substantial antimicrobial activity, limited resistance development, and extensive synergistic effect when combined with other drugs. The effect of AgNPs depends on the delivery system, compound combination, and their own properties, such as shape and size, which are heavily influenced by the synthesis process. Reduction using chemicals or light, irradiation using gamma ray, laser, electron beams or microwave and biological synthesis or a combination of these techniques are notable examples of AgNP synthesis methods. In this work, updated AgNP synthesis methods together with their strength and shortcomings are reviewed. Furthe... [more]
An Electro-Hydraulic-Load-Sensitive System on the Basis of Torque Open-Loop Control
YanWen Li, Cong Yu, Gexin Chen, Mingkun Yang, Yuhang Zhang, Fei Wang
January 12, 2024 (v1)
Keywords: electric construction machinery, load sensitive, pressure control, torque control
Facing the development trend of electrification of construction machinery, in view of the drawbacks of the existing electro-hydraulic-load-sensitive system in terms of dynamic characteristics and usage of energy, based on the drive source of a servo motor-driven quantitative pump, an electro-hydraulic-load-sensitive system on the basis of torque open-loop control was proposed. Firstly, the working principle of the system was introduced and the system’s operating characteristics and energy consumption characteristics were theoretically analyzed. Secondly, in order to balance the system’s energy usage and maneuverability, a control strategy with a variable pressure margin was designed. Meanwhile, in order to solve the problem that the hydraulic pump’s mechanical efficiency causes system pressure control deviation, a torque compensation method based on offline data and speed prediction was proposed. Finally, simulation and testing were used to confirm the viability of the control strategy... [more]
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