The environmental pollution of phenol-containing wastewater is an urgent problem with industrial development. Natural deep eutectic solvents provide an environmentally friendly alternation for the solvent extraction of phenol. This study synthesized a series of natural deep eutectic solvents with L-proline and decanoic acid as precursors, characterized by in situ infrared spectrometry, Fourier transform infrared spectrometry, hydrogen nuclear magnetic resonance spectrometry, and differential thermogravimetric analysis. Natural deep eutectic solvents have good thermal stability. The high-efficiency extraction of phenol from wastewater by natural deep eutectic solvents was investigated under mild conditions. The effects of natural deep eutectic solvents, phenol concentration, reaction temperature, and reaction time on phenol extraction were studied. The optimized extraction conditions of phenol with L-prolin/decanoic acid were as follows: molar ratio, 4.2:1; reaction time, 60 min; and te... [more]

In this paper, we formulate and solve a novel real-life large-scale automotive parts paint shop scheduling problem, which contains color arrangement restrictions, part arrangement restrictions, bracket restrictions, and multi-objectives. Based on these restrictions, we construct exact constraints and two objective functions to form a large-scale multi-objective mixed-integer linear programming problem. To reduce this scheduling problem’s complexity, we converted the multi-objective model into a multi-level objective programming problem by combining the rule-based scheduling algorithm and the adaptive Partheno-Genetic algorithm. The rule-based scheduling algorithm is adopted to optimize color changes horizontally and bracket replacements vertically. The adaptive Partheno-Genetic algorithm is designed to optimize production based on the rule-based scheduling algorithm. Finally, we apply the model to the actual optimization problem that contained 829,684 variables and 137,319 constraints,... [more]

In this paper, a new DEM calibration procedure based on two different types of procedures to compare simulation with experiments is proposed. The aim is to find the values of the interfacial adhesive surface energy and the coefficient of rolling friction between the particles to be used in the simulation. The approach adopted is the so-called Bulk Calibration method. The experimental values of the angle of repose and unconfined yield strength, found with a static testing method and by shear testing, respectively, are compared, respectively, with the angle of repose, found in a simulation reproducing the experimental procedure, and the unconfined yield strength, obtained from an idealized uniaxial testing procedure. The simulated DEM particles are spheres equipped with the Hertz Mindlin with JKR contact model. The results suggest that a bulk calibration approach is not able to provide results that are consistent with two simple bulk property evaluations and, therefore, direct ways to es... [more]

The cancelation of bookings puts a considerable strain on management decisions in the case of the hospitability industry. Booking cancelations restrict precise predictions and are thus a critical tool for revenue management performance. However, in recent times, thanks to the availability of considerable computing power through machine learning (ML) approaches, it has become possible to create more accurate models to predict the cancelation of bookings compared to more traditional methods. Previous studies have used several ML approaches, such as support vector machine (SVM), neural network (NN), and decision tree (DT) models for predicting hotel cancelations. However, they are yet to address the class imbalance problem that exists in the prediction of hotel cancelations. In this study, we have shortened this gap by introducing an oversampling technique to address class imbalance problems, in conjunction with machine learning algorithms to better predict hotel booking cancelations. A c... [more]

An integrated analysis is required to evaluate the performance of control algorithms used in power take-off (PTO) systems for floating wave energy converters (FWECs). However, research on PTO systems based on the existing hydraulic device has mainly focused on the input power generation performance rather than on obtaining maximum power through hydraulic device-based electrical load control. The power generation performance is analyzed based on the control variables of the existing torque control algorithm (TCA); however, the amount of power generation for each control variable changes significantly based on the cycle of wave excitation moments. This paper proposes a control algorithm to obtain the maximum power by modeling a hydraulic-device-based integrated FWEC. It also proposes a TCA that can obtain the maximum power regardless of the period of wave excitation moment. The proposed TCA continuously monitors the power generation output and changes the PTO damping coefficient in the d... [more]

Most photovoltaic (PV) plants conduct operation and maintenance (O&M) by periodical inspection and cleaning. Such O&M is costly and inefficient. It fails to detect system faults in time, thus causing heavy loss. To ensure their operations are at an ideal state, this work proposes an unsupervised method for intelligent performance evaluation and data-driven fault detection, which enables engineers to check PV panels in time and implement timely maintenance. It classifies monitoring data into three subsets: ideal period A, transition period S, and downturn period B. Based on A and B datasets, we build two non-continuous regression prediction models, which are based on a tree ensemble algorithm and then modified to fit the non-continuous characteristic of PV data. We compare real-time measured power with both upper and lower reference baselines derived from two predictive models. By calculating their threshold ranges, the proposed method achieves the instantaneous performance monitoring o... [more]

Precipitation and accumulation of calcium phosphate in granular sludge has attracted research attention recently for phosphate removal and recovery from wastewater. This study investigated calcium phosphate accumulation from granulation stage to steady state by forming heterotrophic granules at different COD/N ratios at 21 and 32 °C, respectively, followed by the transformation of heterotrophic granules to partial nitrifying granules. It was found that mature granules accumulated around 60−80% minerals in granules, much higher than young granules with only around 30% ash contents. In addition, high temperature promoted co-precipitation of hydroxyapatite and calcite in granules with more calcite than hydroxyapatite and only 4.1% P content, while mainly hydroxyapatite was accumulated at the moderate temperature with 7.7% P content. The accumulation of minerals in granules at the high temperature with 75−80% ash content also led to the disintegration and instability of granules. Specific... [more]

Gamma-alumina nanoparticles (γANPs) were obtained from a low-cost process by using natural bauxites. The γANPs materials were characterized by X-ray powder diffraction (XRPD), Fourier-transform infrared spectroscopy (FTIR), Brunauer−Emmett−Teller (BET) theory, scanning electron microscopy (SEM), atomic force microscopy (AFM), and were functionalized with N-cetyl-N, N, N, trimethylammonium bromide (CTAB), leading to CTAB modified γ-alumina nanoparticles (γANPs-CTAB). These novel functionalized γANPs-CTAB were characterized by XRPD, FTIR, and were used as an adsorbent for bisphenol-A (BPA) removal from water. Batch investigations were conducted under different experimental conditions (e.g., adsorbent dose, agitation time, initial concentration, and pH and surfactant loading) in order to optimize BPA adsorption and to identify the adsorption mechanisms in the system γANPs-CTAB-BPA. The effect of pH on the adsorption showed that the quantity of BPA removed increased remarkably until the pH... [more]

Flavonoids are one of the important active ingredients from Acanthopanax senticosus, with a variety of biological functions, such as antioxidant and antibacterial properties. The aim of this work was to investigate enzyme-assisted ultrasonic extraction of A. senticosus flavonoids and their enrichment and antioxidant properties. We found that the optimal extraction process after Box−Behnken response surface optimization had the following parameters: a 3:2 ratio of cellulase to pectinase, enzyme mixture amount of 6960 U g−1, enzyme treatment time of 59.80 min; temperature of 53.70 °C, and pH value of 6.05. The yield of total flavonoids reached 36.95 ± 0.05 mg g−1. The results for different polar solvent enrichments showed that the highest flavonoid (61.0 ± 0.344 mg g−1), polyphenol (24.93 ± 0.234 mg g−1), and saponin (17.80 ± 0.586 mg g−1) contents were observed in the 1-butanol fraction, and the highest polysaccharide content (20.04 ± 0.783 mg g−1) was in the water fraction. Pearson cor... [more]

Greenhouse gases from industrial activities have become a global problem. Emissions management is being developed to raise awareness of the importance of controlling pollution in general and atmospheric emissions in particular. In 2017, the deficit of the rights of issuance in the industrial sectors increased up to 8.3% (verified emissions in 2017 versus allocation in 2017). This trend will increase more at the end of Phase III due to a progressive reduction in allocation. Phase IV will be much more restrictive in allocating emission rights than Phase III. The extra cost of this deficit reinforces the need for industry in general to reduce CO2 and for the paper industry to reduce GHG emissions and generate credits. Old factories are typically identified as sources of pollution in addition to being inefficient compared to new factories. This article discusses the possibilities offered by maintenance actions, whose integration into a process can successfully reduce the environmental impa... [more]

Deep eutectic solvents (DESs) have properties that make them suitable candidates to be used as entrainers for extractive distillation. In the previous work, it was proven that DES(1:2) (tetrabutylammonium bromide: levulinic acid, 1:2, molar ratio) can break the cyclohexane-benzene azeotrope. In the present work, the HBA and HBD ratio and molar concentration of DES were optimized to obtain a better constitute and condition of DES to be utilized in cyclohexane and benzene extractive distillation. The physical properties and structure of the prepared DESs were characterized. Vapor−liquid equilibrium data of the ternary system (benzene + cyclohexane + DESs) were also measured at atmospheric pressure. All experimental equilibrium data were correlated with Wilson, nonrandom two-liquid (NRTL), and universal quasichemical (UNIQUAC) activity coefficient models, from which the coefficient of determination (R2) of the three pseudo-ternary systems fitting was calculated. From the obtained results,... [more]

Considering the advantages that dynamic reactive power (var) equipment (such as synchronous condensers (SCs), which can control var independently and improve voltage stability), SCs are widely used in AC/DC hybrid power grid to provide emergency var and voltage support. In order to evaluate the dynamic var reserve capacity of SCs and analyze the influence of SCs on the operation characteristics of power system, a model with double-infeed line-commutated converter-based high-voltage direct currents (LCC-HVDCs) and SCs is established. Through theoretical derivation and PSCAD/EMTDC simulation, the effects of SCs on the operation characteristics of double-infeed LCC-HVDCs networks are studied. Then, the non-smooth voltage waveform of electromagnetic transient simulation is approximately transformed into smooth waveform by data fitting method. Finally, the processed voltage waveform is searched step by step to explore the boundary of voltage safety region to determine the dynamic var reserv... [more]

In this study, a three-dimensional model with actual clearances was established for a scroll oil pump, and the internal flow was simulated by the CFD method. The internal flows at different rotation angles were studied, and the cavitation and pressure pulsation in the scroll pump under different working conditions were analyzed. The results show that the flow in the two working chambers of the scroll pump is asymmetric due to its structural characteristics and motion mode. The high-pressure pulsation occurs in the working chamber during the end of the suction and the beginning of discharge. Under the action of high-pressure difference, there is a high-speed jet in the clearance between the orbiting and fixed scrolls, which causes a large area of cavitation downstream of the clearance. Under a low suction pressure, cavitation intensifies with the increase in rotating speed, which leads to a decrease in volumetric efficiency. It can effectively improve cavitation by increasing the suctio... [more]

1. Background: Urea is the main product of the nitrogenous breakdown of protein metabolism in mammals. In this study, process intensification for enzymatic hydrolysis of urea by urease enzyme (jack bean urease) was examined in a membrane reactor. 2. Methods: Batch and continuous enzymatic hydrolysis reactions were performed at different substrate concentrations to determine the digestibility and affinity of the substrate with that of the enzyme. The hydrolysate samples were obtained by an optimized continuous enzyme membrane reactor (EMR) coupled with an ultra-filtration membrane (250 kDa). Feed concentration varied from 100 to 500 mg/L. Laboratory experiments were conducted at room temperature (20 ± 1 °C), with a flow rate of 20 mL/min, urease concentration of 0.067 g/L, ionic strength (I = 0, 0.01, 0.05), and ammonium nitrogen addition of (0, 100 mg/L, 200 mg/L, 500 mg/L). Moreover, the effect of ionic strength, ammonium nitrogen concentration, feed concentration, and enzyme concentr... [more]

To understand the phenotypic capabilities of organisms, it is useful to characterise cellular metabolism through the analysis of its pathways. Dynamic mathematical modelling of metabolic networks is of high interest as it provides the time evolution of the metabolic components. However, it also has limitations, such as the necessary mechanistic details and kinetic parameters are not always available. On the other hand, large metabolic networks exhibit a complex topological structure which can be studied rather efficiently in their stationary regime by constraint-based methods. These methods produce useful predictions on pathway operations. In this review, we present both modelling techniques and we show how they bring complementary views of metabolism. In particular, we show on a simple example how both approaches can be used in conjunction to shed some light on the dynamics of metabolic networks.

Atomically precise silver nanoclusters (AgNCs) are small nanostructures consisting of only a few atoms of silver. The combination of AgNCs with cytosine-rich single-stranded oligonucleotides results in DNA-templated silver nanoclusters (DNA-AgNCs). DNA-AgNCs are highly luminescent and can be engineered with reproducible and unique fluorescent properties. Furthermore, using nucleic acids as templates for the synthesis of AgNCs provides additional practical benefits by expanding optical activity beyond the visible spectral range and creating the possibility for color tunability. In this study, we explore DNA oligonucleotides designed to fold into hairpin-loop (HL) structures which modulate optical properties of AgNCs based on the size of the loop containing different number of cytosines (HL-CN). Depending on the size of the loop, AgNCs can be manufactured to have either single or multiple emissive states. Such hairpin-loop structures provide an additional stability for AgNCs and further... [more]

Due to manganese mining and slag accumulation, the geological structure of the wetland polluted by heavy metals in Xiangtan Manganese Mine area was seriously damaged, hence biodiversity loss, severe soil, and water pollution, as well as serious heavy metal pollution to food, vegetables, and other natural sources. In order to restore the ecological environment of the mining area, in 2015, the ecological restoration test of heavy metal polluted wetlands in the mining area was carried out. The results showed that the Mn content of different parts of Koelreuteria paniculata root from high to low order: fine root > small root > medium root > large root. The Mn content of different parts of Elaeocarpus decipiens root from high to low order: large root > medium root > small root > fine root. The order of Mn content in plants of the wetland restoration from high to low is as follows: Canna warscewiezii > Thalia dealbata > Boehmeria > Pontederia cordata > Typha orientalis > Nerium oleander > So... [more]

In order to attain high manufacturing productivity, industry 4.0 merges all the available system and environment data that can empower the enabled-intelligent techniques. The use of data provokes the manufacturing self-awareness, reconfiguring the traditional manufacturing challenges. The current piece of research renders attention to new consideration in the Job Shop Scheduling (JSSP) based problems as a case study. In that field, a great number of previous research papers provided optimization solutions for JSSP, relying on heuristics based algorithms. The current study investigates the main elements of such algorithms to provide a concise anatomy and a review on the previous research papers. Going through the study, a new optimization scope is introduced relying on additional available data of a machine, by which the Flexible Job-Shop Scheduling Problem (FJSP) is converted to a dynamic machine state assignation problem. Deploying two-stages, the study utilizes a combination of discr... [more]

Blue crab (Portunus segnis) proliferation on Tunisian coasts started in 2014/2015. It has heavily impacted the balance of other species, local biodiversity, and fishing activity. Limiting these drawbacks may be achieved through ways promoting crabmeat. For this purpose, two different drying modes were tested: Conventional convective drying (CCD) and interval starting accessibility drying (ISAD) under 45 °C and relative humidity of 40%. Several air velocities were assayed under CCD: 1.5, 2.5, 3.5, and 5 m.s−1. Two different ISAD tests were run with different time-related conditions: drying period of 15 s and tempering period of 15 or 60 s. Drying modes and operating conditions performances were compared through proteins and total polyphenol contents (TPCs) evolution during the treatment. Important polyphenol and protein losses were observed between raw and processed crabmeat. Airflow velocities have a significant effect on crabmeat quality preservation. ISAD method under 15 s/60 s allow... [more]

The forecasting of univariate time series poses challenges in industrial applications if the seasonality varies. Typically, a non-varying seasonality of a time series is treated with a model based on Fourier theory or the aggregation of forecasts from multiple resolution levels. If the seasonality changes with time, various wavelet approaches for univariate forecasting are proposed with promising potential but without accessible software or a systematic evaluation of different wavelet models compared to state-of-the-art methods. In contrast, the advantage of the specific multiresolution forecasting proposed here is the convenience of a swiftly accessible implementation in R and Python combined with coefficient selection through evolutionary optimization which is evaluated in four different applications: scheduling of a call center, planning electricity demand, and predicting stocks and prices. The systematic benchmarking is based on out-of-sample forecasts resulting from multiple cross... [more]

Persistent toxic substances including persistent organic pollutants and heavy metals have been released in high quantities in surface waters by industrial activities. Their presence in environmental compartments is causing harmful effects both on the environment and human health. It was shown that their removal from wastewaters using conventional methods and adsorbents is not always a sustainable process. In this circumstance, the use of microorganisms for pollutants uptake can be seen as being an environmentally-friendly and cost-effective strategy for the treatment of industrial effluents. However, in spite of their confirmed potential in the remediation of persistent pollutants, microorganisms are not yet applied at industrial scale. Thus, the current paper aims to synthesize and analyze the available data from literature to support the upscaling of microbial-based biosorption and bioaccumulation processes. The industrial sources of persistent pollutants, the microbial mechanisms fo... [more]

Traditional hazard and operability analysis (HAZOP) is one of the most widely applied methods for process safety management in process enterprises. Due to its principles based on the conservative and qualitative judgment, it often leads to too conservative risk identification results for the fluorine chemical industry usually with high-risk processes to keep the continuity of production. Most of improved quantitative and semi-quantitative methods are based on the layer of protection analysis (LOPA) to resolve the over-conservative problem of traditional HAZOP with the database of LOPA. However, the improved model, taking LOPA as the main line and HAZOP only as the provider of scenarios and influencing factors, is limited to the fact that LOPA can only analyze complete and independent protection layers (IPLs). Therefore, in order to realize the quantitative or semi-quantitative analysis of disaster causes and consequences, a new semi-quantitative HAZOP method takes HAZOP as the main lin... [more]

The aim of this study was the development and optimization of chitosan and hydroxypropyl methylcellulose (HPMC) in situ gelling systems, loaded with bupivacaine hydrochloride for topical ocular administration. This study is based on the properties of two polymers: chitosan, which has mucoadhesive action and is a pH-sensitive polymer, but also the cellulose derivative hydroxypropyl methylcellulose, a thermosensitive polymer which has mucoadhesive properties and increases the viscosity of systems. The analysis and optimization of in situ gelling systems were performed based on an experimental design and response surface methodology. The following formulation parameters were considered: X1 = chitosan concentration (0.5%, 1%), X2 = HPMC E 5 LV concentration (2%, 5%) and X3 = Chitosan/HPMC E 5 LV ratio (1/1, 2/1). In addition, the parameters to be optimized were represented by the contact angle (CA (°)), viscosity and cumulative percentage of bupivacaine hydrochloride released in vitro. The... [more]

Scientific researchers have applied newly developed technologies, such as sensors and actuators, to different fields, including environmental monitoring, traffic management, and precision agriculture. Using agricultural technology to assist crop fertilization is an important research innovation that can not only reduce the workload of farmers, but also reduce resource waste and soil pollution. This paper describes the design and development of a water-fertilizer control system based on the soil conductivity threshold. The system uses a low-cost wireless sensor network as a data collection and transmission tool and transmits the data to the decision support system. The decision support system considers the change in soil electrical conductivity (EC) and moisture content to guide the application of water-fertilizer, and then improves the fertilization accuracy of the water-fertilizer control system. In the experiment, the proposed water-fertilizer control system was tested, and it was co... [more]

From February 2020, the progressive adoption of measures to contain coronavirus’s contagion has resulted in a sudden change in anthropogenic activities in Italy, especially in Lombardy. From a scientific point of view, this situation represents a unique laboratory for understanding and predicting the consequences of specific measures aimed at improving air quality. In this work, the lockdown effect on Milan’s (Italy) air quality was analyzed. The PM10 and PM2.5 values were measured by the ARPA Lombardia, and the real-time on-road (ROM) air quality monitoring network indicates the seasonality of these pollutants, which typically record the highest values in the coldest months of the year. The 10-year particulate matter concentrations analysis shows a PM10 reduction of 35% from 2010 to 2020. March 2020 data analysis shows an alternation of days with higher and lower particulate matter concentrations; values decrease in pollutants concentrations of 16%, respective to 2018. The complexity... [more]