In this work, a numerical simulation study on the mixing characteristics of multiphase flow in an autoclave was carried out using CFD technology. The Eulerian−Eulerian model and discrete phase model (DPM) were employed to investigate the solid holdup, critical suspension speed, nonuniformity of solid suspension, gas holdup distribution, bubble tracks, and residence time during stirring leaching in the autoclave. Experiments validate the accuracy of the numerical model, and the experimental values correspond well with the simulation results. The numerical simulation results show that the solid−liquid mixing is mainly affected by the axial flow, the best agitation speed is 400 rpm, and increasing the speed further cannot make the mixture more homogenous and buildup occurred above the autoclave. The calculated critical suspension speed is 406 rpm, which is slightly lower than that obtained from the empirical formula. The gas phase is mainly concentrated in the vortex area above the blade.... [more]

Blends combine advantageous characteristics of each species, resulting in products with different flavors and nutritional substances. Moreover, transforming them into powder provides numerous advantages. This work evaluated the properties of three blended foam formulations made from the pulps of tropical red fruits (acerola, guava and pitanga) to determine the foam layer drying kinetics and thermodynamic properties. The foam formulations were prepared by mixing the three pulps in equal proportions (1:1:1), all added with 6% albumin and 1% stabilizing agent. The foams were analyzed for density, volumetric expansion, stability and porosity in six mixing times. Subsequently, they were subjected to drying in an oven with forced air circulation at 4 temperatures, with a layer 0.5 cm thick. Seven mathematical models were fitted to the drying kinetics experimental data to determine the effective diffusivity and thermodynamic properties of the samples. The best mixing times were 5 min for the... [more]

This paper proposed a gas emission prediction method based on feature selection and improved machine learning, as traditional gas emission prediction models are neither accurate nor universally applicable. Through analysis, this paper identified 12 factors that affected gas emissions. A total of 30 groups of typical data for gas outflow were standardized, after which a full subset regression feature selection method was used to categorize 12 influencing factors into different regular patterns and select 18 feature parameter sets. Meanwhile, based on nuclear principal component analysis (KPCA), an optimized gas emission prediction model was constructed where the dimensionality of the original data was reduced. An optimized algorithm set was constructed based on the hybrid kernel extreme learning machine (HKELM) and the least squares support vector machine (LSSVM). The performance of feature parameters adopted in the prediction algorithm was evaluated according to certain metrics. By com... [more]

Cellular response to inflammatory stimuli leads to the production of eicosanoids—prostanoids (PRs) and leukotrienes (LTs)—and signaling molecules—cytokines and chemokines—by macrophages. Quantitative modeling of the inflammatory response is challenging owing to a lack of knowledge of the complex regulatory processes involved. Cybernetic models address these challenges by utilizing a well-defined cybernetic goal and optimizing a coarse-grained model toward this goal. We developed a cybernetic model to study arachidonic acid (AA) metabolism, which included two branches, PRs and LTs. We utilized a priori biological knowledge to define the branch-specific cybernetic goals for PR and LT branches as the maximization of TNFα and CCL2, respectively. We estimated the model parameters by fitting data from three experimental conditions. With these parameters, we were able to capture a novel fourth independent experimental condition as part of the model validation. The cybernetic model enhanced ou... [more]

Packed-bed bioreactors are often used for aerobic solid-state fermentation, since the forced aeration supplies O2 and removes metabolic heat from the bed. Motivated by the potential for applications in biorefineries, we review studies conducted on packed-bed bioreactors over the last decade, evaluating the insights these studies provide into how large-scale packed beds should be designed and operated. Many studies have used low superficial air velocities and suffer from preferential airflow, such that parts of the bed are not properly aerated. Moreover, some studies have proposed ineffective strategies, such as reversing the direction of the airflow or introducing air through perforated pipes within the bed. Additionally, many studies have used narrow water-jacketed packed-bed bioreactors, but these bioreactors do not reflect heat removal in wide large-scale packed beds, in which heat removal through the side walls makes a minor contribution. Finally, we conclude that, although some at... [more]

Facility layout in a manufacturing system is a complex production activity because decisions on layout design are influenced by numerous, ambiguous, and competing factors. This study proposes a method for determining and choosing an ideal layout using a hybridized Fuzzy Analytic Hierarchy Process (F-AHP) with the Fuzzy Technique for Order of Preference by Similarity to the Ideal Solution (F-TOPSIS). The F-AHP is used, in this case, because of its ability to generate design criteria weight. The railcar industrial case study results indicate that the developed model can effectively lead to selection of the most suitable facility layout design. The Discrete Event Simulation model is used to evaluate the performance of the suggested layout concepts with the purpose of determining quantitative criteria for use when selecting the most optimal concept by the proposed Fuzzy AHP-TOPSIS model. The proposed methodology demonstrated that a framework is a logical way to solve problems. The proposed... [more]

Silver is an important industrial raw material, and the price of silver has always been a concern of the financial industry. Silver price data belong to time series data and have high volatility, irregularity, nonlinearity, and long-term correlation. Predicting the silver price for economic development is of great practical significance. However, the traditional time series prediction models have shortcomings, such as poor nonlinear fitting ability and low prediction accuracy. Therefore, this paper presents a novel hybrid model of CNN-SA-NGU for silver closing price prediction, which includes conventional neural networks (CNNs), the self-attention mechanism (SA), and the new gated unit (NGU). A CNN extracts the feature of input data. The SA mechanism captures the correlation between different eigenvalues, thus forming new eigenvectors to make weight distribution more reasonable. The NGU is a new deep-learning gated unit proposed in this paper, which is formed by a forgetting gate and a... [more]

This article reports a successful development of the induction heating process (IHP) in a jewelry factory based on experiments and multiphysics consisting of electromagnetic and thermal simulations. First, two experiments were set to measure essential parameters for result validation and multiphysics boundary condition settings. Then, the essential parameters were applied to multiphysics, and both simulation results revealed heat transfer, magnetic flux density (B) generated by the coil, and temperature (T) of the product. B and T were consistent with the experimental results and theory, confirming the reliability of the multiphysics and methodology. After that, all simulation results were analyzed to assess and optimize IHP in terms of the number of coil turns (N), positional placement of the product (P), and coil thickness (Th). Multiphysics revealed that the current operating condition with N = 3 is proper; however, the IHP can be improved more with coil and operating condition opti... [more]

In this paper, the interaction mechanism between the solid−liquid−gas interface phenomenon caused by nanostructure and surface wettability and boiling heat transfer is described, and the heat transfer theory of single wettable nanostructure surface and mixed wettable nanostructure surface is proposed. Through molecular dynamics simulation, the thermodynamic model of the wettable surface of nanostructures is established. The nanostructures are set as four rectangular lattice structures with a height of 18 Å. The solid atoms are platinum atoms, and the liquid atoms are argon atoms. The simulation results show that with the increase of surface hydrophilicity of nanostructures, the fluid temperature increases significantly, and the heat transfer at the interface is enhanced. With the increase in surface hydrophobicity of nanostructures, the atoms staying on the surface of nanostructures are affected by the hydrophobicity, showing a phenomenon of exclusion, and the evaporation rate in the e... [more]

Gravure printing is widely used in food, pharmaceutical, and other packaging industries. As a green printing material, water-based ink has problems such as non-volatile and poor drying on non-absorbent packaging substrates, which has a great impact on its application. To solve these difficulties, this study adopts the volume of fluid (VOF) method and user-defined function (UDF) to establish a multiphase flow impinging air jets drying model of water-based ink in the gravure printing process, taking a water-based ink droplet as an example. The model was used to simulate the ink drying state in the impinging air jets region and analyze the effects of impinging air jets’ temperature and velocity, as well as ink viscosity and thickness, on the ink drying efficiency. Meanwhile, the heat and mass transfer mechanism between impinging air jets and water-based ink was investigated. The results show that the higher impinging air jet temperature and velocity, the faster the drying rate of the ink;... [more]

In this paper a CFD analysis of HIsarna off-gas system for post combustion of CO-H2-carbon particle mixture is presented to evaluate the effect of different sub-models and parameters on the accuracy of predictions and simulation time. The effects of different mesh type, mesh grid size, radiation models, turbulent models, kinetic mechanism, turbulence chemistry interaction models, including and excluding gas-solid reactions, number of reactive solid particles are investigated in detail. Based on the accuracy of the predictions and agreement with counterpart measured values, the best combination is selected and conclusions are derived. It was found that radiation and turbulence chemistry interaction model have a major effect on the temperature and composition profile prediction along the studied off-gas system, compared to the variations in other models. The effect of these two models becomes even more evident when the temperature and fuel content of the flue gas are high.

Parenteral products appear to be sensitive to process conditions in bioprocessing steps, such as interfacial stress and shear stress. The combination of these elements is widely believed and proven to influence product stability, but the defined roles of these players in the product damage process have not yet been identified. The present work addresses a current industrial problem, by focusing on the analysis of shear stress on protein-based therapeutics flowing in tubing by means of Computational Fluid Dynamics simulations. The purpose of this article is not to pinpoint the mechanism triggering the damage of the product, but it represents the first step towards wider experimental investigations and introduces a new strategy to quantify the average shear stress. The field of scale-down approaches, used to scale the commercial process down to the laboratory level, is also explored. Since quality control is critical in the pharmaceutical realm, it is essential that the scale-down approa... [more]

The rapid changes in nanotechnology over the last ten years have given scientists and engineers a lot of new things to study. The nanofluid constitutes one of the most significant advantages that has come out of all these improvements. Nanofluids, colloid suspensions of metallic and nonmetallic nanoparticles in common base fluids, are known for their astonishing ability to transfer heat. Previous research has focused on developing mathematical models and using varied geometries in nanofluids to boost heat transfer rates. However, an accurate mathematical model is another important factor that must be considered because it dramatically affects how heat flows. As a result, before using nanofluids for real-world heat transfer applications, a mathematical model should be used. This article provides a brief overview of the Tiwari and Das nanofluid models. Moreover, the effects of different geometries, nanoparticles, and their physical properties, such as viscosity, thermal conductivity, and... [more]

This paper proposes a self-sustaining control model for proton-exchange membrane (PEM) electrolysis devices, aiming to maintain the temperature of their internal operating environment and, thus, improve the electrolysis efficiency and hydrogen production rate. Based on the analysis of energy−substance balance and electrochemical reaction characteristics, an electrothermal-coupling dynamic model for PEM electrolysis devices was constructed. Considering the influence of the input energy−substance and the output hydrogen and oxygen of PEM electrolysis devices on the whole dynamic equilibrium process, the required electrical energy and water molar flow rate are dynamically adjusted so that the temperature of the cathode and the anode is maintained near 338.15 K. The analytical results show that the hydrogen production rate and electrolysis efficiency are increased by 0.275 mol/min and 3.9%, respectively, by linearly stacking 100 PEM electrolysis devices to form a hydrogen production system... [more]

Monoliths are promising as catalytic structured supports due to their many operational advantages. Compared to pellets, monoliths offer low backpressure and good heat distribution, even at high flow rates. There is interest in the industry for improving temperature control in highly exothermic systems, such as the catalytic hydrogenation of CO2 for e-fuels synthesis. In this context, novel substrate shapes, such as non-homogeneous cell density monoliths, show good potential; however, to date, they have only been sparsely described. This work focuses on a dual cell density substrate and uses a computational model of a straight-channel monolith with two concentric regions to analyze its flow distribution. The central (core) and peripheral (ring) regions of the substrate differ in cell density in order to obtain a non-homogeneous cross-section. The model is validated against classical data in the literature and theoretical equations. Then, the flow fraction passing through each region of... [more]

Microwave heating has excellent potential for applications in wastewater treatment. This study proposes a highly efficient continuous liquid-phase microwave heating system to overcome the problems of low treatment capacity, low dynamic range of loads, and insufficient heating uniformity of the existing equipment. First, a quarter-wavelength impedance-matching layer improves heating efficiency, and the heating uniformity has been enhanced by horn antennas. Second, an experimental system is developed. The simulation and experimental results are consistent, with the microwave system achieving over 90% energy utilization for different thicknesses and concentrations of salt water. Finally, simulations are performed to analyze microwave efficiency and heating uniformity at different flow rates, salinities, dielectric properties, and sawtooth structures. The system can efficiently heat loads with a wide range of dielectric properties, including saline water. Generally, when the permittivity v... [more]

In this paper, the Multisphere (MS) models of three varieties of Cyperus esculentus seeds are modeled based on DEM. In addition, for comparison, other particle models based on automatic filing in EDEM software are also introduced. Then, the direct shear test, piling test, bulk density test, and rotating hub test are used to verify the feasibility of particle models of Cyperus esculentus seeds that we proposed. By comparing the simulated results and experimental results, combined with the CPU computation time, the proposed particle models achieved better simulation accuracy with fewer filing spheres. According to simulation results, some limitation was present when using one single verification test; varieties of verification tests used could improve the verification reliability, and a more appropriate particle model could be selected. Additionally, the issue of multicontact points in the MS model was studied. The Hertz Mindlin (no slip) (HM) model and Hertz Mindlin new restitution (HMN... [more]

Windage power loss plays a leading role in the total power loss of high-speed gears, which seriously affects the transmission efficiency of gear systems and leads to high energy consumption. This paper proposes a negative pressure regulation method to reduce windage power loss. Based on the computational fluid dynamics theory, the flow field distribution and windage power loss in the gearbox under different negative pressure conditions are studied, and the effect of the negative pressure environment and speed on the windage power loss is obtained. In order to further save calculation costs, an optimization algorithm of the BP neural network based on a genetic algorithm is proposed to effectively predict the windage power loss. The results show that the high-speed airflow near the tooth’s surface will produce a large pressure moment, which is the main cause of wind resistance loss. The windage power loss increases with the increase in the negative pressure or speed of the gearbox, but t... [more]

Temperature changes in CO2 foam-fracturing construction can easily affect surfactant foam stability. To investigate the effect of temperature on the foam stability of different types of surfactants, this study measured the foam half-life and viscosity of four typical surfactants, CTAB, LAS-30, HSB1214, and TX-10, using a novel self-designed and built foam performance measurement device. The effects of temperature on foam half-life and viscosity were studied. The results show that as the temperature increased, the half-life shortened, and the viscosity of the liquid phase decreased, which led to a decrease in foam stability. Moreover, using Materials Studio, a type of molecular simulation software, an interfacial model of the foam film was constructed to calculate the IFE and the self-diffusion coefficient of water molecules at 300 ps after the equilibrium of the foam system to investigate the mechanism of temperature influence on the stability of the foam. The results show that, for CT... [more]

Smart factories are equipped with Industry 4.0 technologies including smart sensors, digital twin, big data, and embedded software solutions. The application of these technologies contributes to better decision-making, and this real-time decision-making can improve the efficiency of both manufacturing and related logistics processes. In this article, the transformation of conventional milk-run-based in-plant supply solutions into a cyber−physical milk-run supply is described, where the application of Industry 4.0 technologies makes it possible to make real-time decisions regarding scheduling, routing, and resource planning. After a literature review, this paper introduces the structure of Industry 4.0 technologies supported by milk-run-based in-plant supply. A mathematical model of milk-run processes is described including both scheduling and routing problems of in-plant supply. This mathematical model makes it possible to analyze the impact of Industry 4.0 technologies on the efficien... [more]

In a ball screw feed system of high-speed/high-acceleration machine tools, large frictional and inertial forces may change the real contact state of the kinematic joints, resulting in changes in the contact and transmission stiffnesses and, hence, changes in the dynamic characteristics of the system. In this study, a variable−coefficient dynamic modeling method for a ball screw feed system is proposed, considering the influence of changes in the no-extra-load running states, such as position, speed, and acceleration. Based on Timoshenko beam elements with two nodes and four DOFs, an equivalent dynamic model of a ball screw feed system is established using the hybrid element method. The expression for the equivalent axial stiffness of individual kinematic joints is derived, considering the influence of the feed speed/acceleration under the no-extra-load running state of the system. In addition, the stiffness and mass of the screw shafts on both sides of the screw nut are calculated, con... [more]

Submerged arc welding is a complex metallurgical system involving various phases with a temperature higher than 2000 °C. Since the hot weld pool is shielded beneath the flux, thermodynamic investigation on the O content variation during the welding process remains nebulous. Within this framework, a thermodynamic approach has been proposed to estimate the variation tendency of O content in metal during the overall submerged arc welding process. The modeling is based on the assumptions of Oxygen Layer Theory, Local Attained Equilibrium, and Scheil Solidification. The simulated and measured data show that this approach is capable of predicting the variation of the O content roadmap when typical CaO−Al2O3 based fluxes are employed. Then, factors pertinent to the level of O content are evaluated from thermodynamic perspectives. Additionally, it is revealed that the decomposition mechanisms of the oxides in welding can be constrained via the incumbent approach.

The very useful organic solvent 2-octanol is widely employed in the industry, and the direct hydration of olefins is an important method for its production. However, a slow transfer rate during a reaction due to the poor mutual solubility of the reactants is a problem; a cosolvent can be used to solve it. In this study, the feasibility of using the direct hydration of 1-octene via a catalytic distillation process using 1,4-dioxane as a cosolvent was investigated. First, the COSMOtherm program was used to identify and screen many typical cosolvents. Subsequently, the kinetics of the direct hydration reaction of 1-octene using 1,4-dioxane as a cosolvent and an HZSM-5 molecular sieve as the catalyst were determined experimentally. Finally, kinetic and thermodynamic models were utilized to create non-reactive and reactive residual curve maps to assess the feasibility of proceeding with the reaction. Applying a suitable Damköhler number (Da) value and the residual curve changes demonstrated... [more]

Plastic collapse and buckling are the key structural failure criteria in 3D concrete printing (3DCP). This study aims to analyze the effect of different geometrical designs and printing factors on the buildability performance of 3DCP structures. Due to the high number of variables involved, the Design of Experiment (DOE) has been used to reduce the number of simulations. In geometrical design parameters, the structure’s design is more sensitive, followed by the width and length of the printed design. The buildability increases when we move from sharp corners to more stable structures like fillets and circular geometry. For geometrical design parameters, a maximum buildability of 74% of the designed height is achieved for circular design with the highest width and lowest diameter. For printing parameters, the highest buildability of 486 mm (81%) is achieved for the lower values of printing speed and layer height. The study analyzed failure phenomena of buckling and yield strength for th... [more]

Geological carbon sequestration is a proven method of safely storing carbon dioxide in formations, thereby reducing atmospheric carbon imprint and mitigating global warming. The relative permeability to carbon dioxide versus brine/water in geological formations determines flow characteristics of one fluid in the presence of another. The objective of this research is to evaluate the relative permeability to carbon dioxide in both the gas phase and the supercritical state in the presence of water in a Vedder sandstone core sample. The sandstone sample used is medium- to fine-grain arkosic artenite containing primarily quartz, potassium feldspar, plagioclase, and biotite. The effect of the viscosity ratio between the non-wetting phase and the wetting phase, on the relative permeability to the non-wetting phase, is studied. Computational fluid dynamics (CFD) is used for this study. Results show that with the same amount of irreducible water fraction, the endpoint relative permeability to t... [more]