An experimental study on the flow pattern dynamics in a standard mixing vessel with radial baffles filled with water and induced by a pitched blade impeller pumping downward is presented. Investigation is mainly focused on detection and analysis of quasi-periodical or periodical low-frequency phenomenon connected with time- and length-scales considerably exceeding the Blade Passage Frequency (hereinafter BPF) and common turbulent eddies. This phenomenon, which is expressed as large-scale mean-flow variations, is generally known as flow Macro-Instability (hereinafter MI). It could break-down just below the liquid surface, or it crashes to the liquid surface and causes its Macro-Swelling (hereinafter MS). Our investigation was based on classical two-dimensional (2D) Particle Image Velocimetry (hereinafter PIV) measurement within 3 selected vertical planes in the vessel and subsequent analysis of the velocity field. The dominant frequencies evaluated in the selected points and overall ana... [more]

Variable selection constitutes an essential step to reduce dimensionality and improve performance of fault detection and diagnosis in large scale industrial processes. For this reason, in this paper, variable selection approaches based on causality are proposed and compared, in terms of model adjustment of available data and fault detection performance, with several other filter-based, wrapper-based, and embedded-based variable selection methods. These approaches are applied in a simulated benchmark case and an actual oil and gas industrial case considering four different learning models. The experimental results show that obtained models presented better performance during the fault detection stage when variable selection procedures based on causality were used for purpose of model building.

Stunting is one of the public health problems that has yet to be solved in Indonesia. This study developed synbiotic fermented milk with iron and zinc fortification that was then tested in a clinical setting. The product was made from skimmed milk and fructooligosaccharides (FOS) and fermented with Lactobacillus plantarum. A sample of 94 stunted children under five years old were randomly assigned to intervention or control groups. The intervention group received double-fortified synbiotic milk, while the control group drank non-fortified milk. After three months, the number of normal children in both groups, according to weight- or height-for-age z-score category, was found to be increasing. However, the difference between the two groups was not significant (p > 0.05). The study suggests that fermented milk may have a good effect on child growth. Further research is needed to deepen the potency of synbiotic fermented milk for stunted children.

An input-series output-parallel soft switching resonant circuit with balance input voltage and primary-side current is studied and implemented for direct current (DC) microgrid system applications. Two resonant circuits are connected with input-series and output-parallel structure to have the advantages of low voltage stresses on active devices and low current stresses on power diodes. A balance capacitor is adopted on high voltage side to balance two input capacitor voltages. The LLC (inductor−inductor−capacitor) resonant circuit cells are employed in the converter to have soft switching operation for power semiconductors. The magnetic coupling component is adopted on the primary-side to automatically realize current balance of the two resonant circuits. In the end, a laboratory hardware circuit is built and tested. Experiments demonstrate and prove the validity of the resonant converter.

Water scarcity due to the ever-increasing worldwide demand and climate change is one of the greatest hurdles of our time [...]

In the present study, a Box−Behnken design of response surface methodology (RSM) was employed to optimize the processing factors (force: 100, 150, and 200 kN; speed: 3, 5, and 7 mm/min; and temperature: 40, 60, and 80 °C) for extracting pumpkin seeds oil under uniaxial compression. The design generated 15 experiments including twelve combinations of factors and three replicates at the center point. The responses: oil yield (%), oil expression efficiency (%), and energy (J) were calculated, and the regression models determined were statistically analyzed and validated. The optimum factors combination: 200 kN, 4 mm/min and 80 °C predicted the oil yield of 20.48%, oil expression efficiency of 60.90%, and energy of 848.04 J. The relaxation time of 12 min at the optimum factors increased the oil efficiency to 64.53%. The lower oil point force was determined to be 57.32 kN for estimating the maximum oil output. The tangent curve and generalized Maxwell models adequately (R2 = 0.996) describe... [more]

Efficient monitoring is an open problem in the operation of anaerobic digestion processes, due to the lack of accurate, low-cost, and proper sensors for the on-line monitoring of key process variables. This paper presents two approaches for the indirect monitoring of the anaerobic digestion of cheese whey wastewater. First, the observability property is addressed using conventional and nonconventional techniques, including an observability index. Then, two model-based observer techniques, an extended Luenberger observer, a sliding mode observer, and a data-driven technique based on fractal analysis are formulated and discussed. The performance and capabilities of the proposed methodologies are illustrated on a validated model with experimental data of the anaerobic digestion of cheese whey. Experimental pH measurements are used for the data-driven approach based on fractal analysis. The experimental data sets correspond to experimental conditions (pH > 7.5 and temperature (T) = 40 °C)... [more]

The increasing clinical use of artificial medical devices raises the issue of microbial contamination, which is a risk factor for the occurrence of biofilm-associated infections. A huge amount of scientific data highlights the promising potential of essential oils (EOs) to be used for the development of novel antibiofilm strategies. We aimed to review the relevant literature indexed in PubMed and Embase and to identify the recent directions in the field of EOs, as a new modality to eradicate microbial biofilms. We paid special attention to studies that explain the mechanisms of the microbicidal and antibiofilm activity of EOs, as well as their synergism with other antimicrobials. The EOs are difficult to test for their antimicrobial activity due to lipophilicity and volatility, so we have presented recent methods that facilitate these tests. There are presented the applications of EOs in chronic wounds and biofilm-mediated infection treatment, in the food industry and as air disinfecta... [more]

The development of efficient methods for process performance verification has drawn a lot of attention in the research community. Viability theory is a mathematical tool to identify the trajectories of a dynamical system which remains in a constraint set. In this paper, viability theory is investigated for this purpose in the case of nonlinear processes that can be represented in Linear Parameter Varying (LPV) form. In particular, verification algorithms based on the use of invariance and viability kernels and capture basin are proposed. The difficulty with the application of this theory is the computation of these sets. A Lagrangian method has been used to approximate these sets. Because of simplicity and efficient computations, zonotopes are adopted for set representation. Two new sets called Safe Work Area (SWA) and Required Performance (RP) are defined and an algorithm is proposed to use these concepts for the verification purpose. Finally, two application examples based on well-kn... [more]

Ionic liquids can typically be synthesized via protonation, alkylation, metathesis, or neutralization reactions. The many types of ionic liquids have increased their attractiveness to researchers for employment in various areas, including in polymer composites. Recently, ionic liquids have been employed to modify nanofillers for the fabrication of polymer nanocomposites with improved physicochemical properties. In this succinct review, four types of imidazolium-based ionic liquids that are employed as modifiers—specifically alkylimidazolium halide, alkylimidazolium hexafluorophosphate, alkylimidazolium tetrafluoroborate, and alkylimidazolium bistriflimide—are reviewed. Additionally, three types of ionic liquid-modified nanofiller/polymer nanocomposites—namely ionic liquid-nanofiller/thermoplastic nanocomposites, ionic liquid-nanofiller/elastomer nanocomposites, and ionic liquid-nanofiller/thermoset nanocomposites—are described as well. The effect of imidazolium-based ionic liquids on t... [more]

Continuous manufacturing has received increasing interest because of the advantages of intrinsic safety and enhanced mass transfer in the pharmaceutical industry. However, the difficulty for scale-up has limited the application of continuous manufacturing for a long time. Recently, the tubular flow reactor equipped with the Kenics static mixer appears to be a solution for the continuous process scale-up. Although many influence factors on the mixing performance in the Kenics static mixer have been investigated, little research has been carried out on the aspect ratio. In this study, we used the coefficient of variation as the mixing evaluation index to investigate the effect of the aspect ratio (0.2−2) on the Kenics static mixer’s mixing performance. The results indicate that a low aspect ratio helps obtain a shorter mixing time and mixer length. This study suggests that adjusting the aspect ratio of the Kenics static mixer can be a new strategy for the scale-up of a continuous process... [more]

The lateral migration of elastic capsules towards a microchannel centerline plays a major role in industrial and physiological processes. Via our computational investigation, we show that a constriction connecting two straight microchannels facilitates the lateral capsule migration considerably, which is relatively slow in straight channels. Our work reveals that the significant cross-streamline migration inside the constriction is dominated by the strong hydrodynamic forces due to the capsule size. However, in the downstream straight channel, the increased interfacial deformation at higher capillary numbers or a lower viscosity ratio and lower membrane hardness results in increased lateral cross-streamline migration. Thus, our work highlights the different migration mechanisms occurring over curved and straight streamlines.

The segregation process of a single large intruder in a vibrated bed of small particles has been widely studied, but most previous studies focused on spherical intruders. In this work, the discrete element method was used to study the effects of vibration conditions and intruder shape on the dimensionless ascending velocity (va) of the intruder. The intruder was in a prolate shape with aspect ratio varied but its equivalent diameter fixed. Three equivalent diameters, namely volume-equivalent diameter, surface-area-equivalent diameter, and Sauter diameter, were used. It was found that va increases and then decreases with the rise of the dimensionless vibration amplitude (Ad) and the dimensionless vibration frequency (fd), and va increases with the decrease of the sphericity of the intruder (Φ). Moreover, the porosity variation in the vibrated bed and the granular temperature were analyzed, which can be linked to the change of va. It was further found that va can be uniformly correlated... [more]

In bio-oil upgrading, the activity and stability of the catalyst are of great importance for the catalytic hydrodeoxygenation (HDO) process. The vapor-phase HDO of guaiacol was investigated to clarify the activity, stability, and regeneration ability of Al-MCM-41 supported Pd, Co, and Fe catalysts in a fixed-bed reactor. The HDO experiment was conducted at 400 °C and 1 atm, while the regeneration of the catalyst was performed with an air flow at 500 °C for 240 min. TGA and XPS techniques were applied to study the coke deposit and metal oxide bond energy of the catalysts before and after HDO reaction. The Co and Pd−Co simultaneously catalyzed the CArO−CH3, CAr−OH, and multiple C−C hydrogenolyses, while the Fe and Pd−Fe principally catalyzed the CAr−OCH3 hydrogenolysis. The bimetallic Pd−Co and Pd−Fe showed a higher HDO yield and stability than monometallic Co and Fe, since the coke formation was reduced. The Pd−Fe catalyst presented a higher stability and regeneration ability than the P... [more]

This study investigates the effects of sodium nitrite replacement by the sage essential oil (SEO), on the physico-chemical, microbiological and sensory quality of dry fermented sausages (DFS) during 225 days of storage. The SEO (0.00, 0.05 and 0.10 µL/g) was added in DFS batters formulated with different levels of pork back fat (15% and 25%) and sodium nitrite (0, 75 and 150 mg/kg). The inclusion of SEO had no negative impact on pH, color (instrumental and sensory) and texture parameters. Total plate counts were lower than 6 log CFU (colony forming units)/g in all samples throughout the storage. Furthermore, the addition of SEO at concentration of 0.05 µL/g provided acceptable TBARS (2-Thiobarbituric acid reactive substances) values (<0.3 mg MDA (malondialdehyde)/kg) in the samples produced with reduced levels of sodium nitrite (0 and 75 mg/kg) without negative alternations on sensory attributes of odor and flavor. Generally, our findings confirmed that the usage of SEO could be a g... [more]

In order to improve the resistance to thermal fatigue and wear resistance of H13 hot-working tool steel, a nickel-based composite coating was prepared on its surface by laser cladding technology. The relationship was studied between the main processing parameters and the size of the cladding layer such as height and width. Based on the orthogonal polynomial regression method, the relationships were modeled mathematically between laser power, scanning speed, powder feeding voltage and microhardness. This model was proved to be able to predict the laser power and powder feeding voltage under 1100 Hv microhardness.

In order to improve the structural stiffness of the gravure cell structure in the solid printing process and realize a lightweight design, a multi-objective optimization design method was proposed to optimize the parameters of the direct laser engraving of the cell structure. In this paper, based on the characteristics of the cell structure and the analysis of the contact force, the ANSYS parametric design language (APDL) was used to conduct a finite element analysis on the microstructure of the regular hexagonal cell. We found that there is a certain optimization space. Then, a response surface (RSM) method optimization model, using a central composite design (CCD), was established to obtain, and then analyze, the sensitivity of each design variable to the objective functions. Finally, a multi-objective genetic algorithm (MOGA) was used to solve the model. The optimization results show that the maximum deformation was reduced by 44.4%, and the total volume was reduced by 46.3%. By com... [more]

Steelmaking based on direct reduced iron (DRI, and its compacted derivative hot briquetted iron, HBI) is an anticipated important global alternative to current steel production based on FeOx reduction in blast furnaces due to its lower specific CO2 emission. The majority of DRI is melted and refined in the electric arc furnace with different process conditions compared to the melting of steel scrap due to its raw material composition being rather different. We provide data and analysis of slag composition of DRI charges vs. steel scrap charges for 16 industrial electric arc furnaces (EAFs). Suggestions for optimized slag operation and resulting process improvements of DRI melting in the EAF are given. A dynamic mass and energy model of the DRI melting in the EAF is introduced to illustrate the implications of the adapted slag operation on the EAF process with DRI charges.

A comparative study of two corn nixtamalization processes is presented, one in the traditional way of the Michoacan region of Mexico, and the other using solar devices. The corn selected for the process was a nontransgenic endemic dark corn. For the nixtamalization process, a solar concentration oven was used; this process using the solar device is simple and affordable for communities. For characterization, the properties of the antioxidant content of dark corn were analyzed for both processes, and the highest concentration of antioxidants between the two varieties of corn was obtained. The antioxidant capacity in the two varieties of black corn was quantified and determined, and the anthocyanin pigments were extracted with methanol. The total anthocyanin content (CAT) was evaluated by the pH difference method, and the antioxidant capacity by the DPPH method. In the solar nixtamalization process, a higher content of CAT anthocyanins and antioxidant capacity were obtained. Therefore, t... [more]

Praseodymium (Pr)-promoted MCM-41 catalyst was investigated for the catalytic decomposition of methyl mercaptan (CH3SH). Various characterization techniques, such as X-ray diffraction (XRD), N2 adsorption−desorption, temperature-programmed desorption of ammonia (NH3-TPD) and carbon dioxide (CO2-TPD), hydrogen temperature-programmed reduction (H2-TPR), and X-ray photoelectron spectrometer (XPS), were carried out to analyze the physicochemical properties of material. XPS characterization results showed that praseodymium was presented on the modified catalyst in the form of praseodymium oxide species, which can react with coke deposit to prolong the catalytic stability until 120 h. Meanwhile, the strong acid sites were proved to be the main active center over the 10% Pr/MCM-41 catalyst by NH3-TPD results during the catalytic elimination of methyl mercaptan. The possible reaction mechanism was proposed by analyzing the product distribution results. The final products were mainly small-mole... [more]

This article introduces a novel laboratory-scale process for the electrochemical synthesis of hydrogen peroxide (H2O2). The process aims at an energy-efficient, decentralized production, and a mathematical optimization of it is presented. A dynamic, zero-dimensional mathematical model of the reactor is set up in Aspen custom modeler®. The proposed model constitutes a reasonable compromise between complexity and convergence. After thoroughly determining the reaction kinetics by adjustment to experimental data, the reactor unit is embedded in an Aspen Plus® flowsheet in order to investigate its interaction with other unit operations. The downstream contains another custom module for membrane distillation. Electricity appears as a resource in the process, and optimization shows that it reaches product purities of up to 3 wt.-%. Both the process optimization and the adjustment of the reaction kinetics are treated as multi-criteria optimization (MCO) problems.

Solid-state fermentation requires the development of more efficient cultivation systems for its industrial application. The objective of this work was to evaluate the effect of aeration regime on the production of biomass and several lignocellulolytic enzymes (laccase, manganese peroxidase, endoxylanase, β-glucosidase, and total cellulases) by Trametes versicolor in a novel fixed-bed solid-state pilot-scale bioreactor. Three regimes were assessed: natural convection, low aeration level (10 min every 6 h at 10 L/h air flowrate), and high aeration level (1 h every 6 h at 10 L/h air flowrate). The mushroom was grown on a medium based on lignocellulosic residues. The design of the bioreactor, as well as the control of aeration, humidity, and temperature of the beds, allowed T. versicolor to grow properly on the medium, reaching a maximum biomass production of 204.7 mg/g dry solid (ds). The influence that aeration regime had on the production of lignocellulolytic enzymes was determined. Low... [more]

Solvent extraction is one of the common methods for the recovery of boric acid (or boron) from aqueous solutions. A wide variety of different compounds including monohydric alcohols has been tested, and there is wide recognition that they are rather ineffective compared to other extractants such as diols. Nevertheless, monohydric alcohols find application in industrial processes, demonstrating their efficiency. The intention of this study is to clarify this discrepancy and to provide an overall picture of monohydric alcohols as an extractant for boric acid. Five different monohydric alcohols are the object of this study: n-octanol, 2-ethyl-1-hexanol, 2-butyl-1-octanol, 2-octanol and 3,7-dimethyl-3-octanol. A special focus of this work is the examination of the effect of the structure of the carbon chain and the effect of the composition of the aqueous phase on the extraction efficiency. As well as the extraction efficiency for boric acid, other important properties are examined such as... [more]

Pesticide by-products found in soil are usually more toxic and persistent than the pesticides themselves. For example, Endosulfan lactone (EL) (a by-product of the organochloride pesticide endosulfan). EL is created by the enzymatic activity (and related oxidative processes) of microorganisms in the soil. A sustainable method of EL removal is the introduction of Eisenia fetida earthworm. In this paper, it will be demonstrated the impact of vermicomposting process related to Eisenia fetida earthworm on EL by measuring initial and final concentrations of the compound and overall enzymatic activity in sterile and non-sterile solid substrate over 56 days. As a baseline, it be observed there were higher EL removals in non-sterile solid substrate (90.86%) at day 5 than in sterile solid substrate (83.86%) at day 14. In samples with Eisenia fetida, the presence of EL in non-sterile solid substrate was 36%, however in sterile solid substrate it was only 18% at day 1 and 7, with a maximum enzyme... [more]

An absorption air-conditioning system is a good choice for green buildings. It has the superiority in the utilization of renewable energy and the refrigerant is environment-friendly. However, the performance of the traditional absorption system has been restricted by the energy waste in the thermal regeneration process. Capacitive deionization (CDI) regeneration is proposed as a potential method to improve system efficiency. In the new method-based air-conditioning system, strong absorbent solutions and pure water are acquired with the joint work of two CDI units. Nevertheless, the practical CDI device is composed of a lot of CDI units, which is quite different from the theoretical model. To reveal the performance of multiple CDI units, the model of the double/multi-stage CDI system has been developed. Analysis has been made to expose the influence of some key parameters. The results show the double-stage system has better performance than the single-stage system under certain conditio... [more]