We were not aware of an error made in the proofreading phase; therefore, we wish to make the following correction to Figure 1b from this paper [...]

Recently, studies about smoked food tend to identify harmful compounds that potentially appear within the smoking process. The process, conducted in a smokehouse, closely corresponds with the design and method. This paper presents a smokehouse designed by integrating a biomass furnace, a heat exchanger, a cyclone separator, and a smoking chamber. The design target was to obtain a smoking system that produces clean smoked fish. The design and construction phase and the performance tests phase are discussed in this paper. The energy source used was coconut shells, fed into the furnace at predetermined amounts, to achieve the desired temperature. The performance tests were done using skipjack fish, whose weight ranged from 0.7−1.0 kg/head. The results showed that the smoking system was able to complete the smoking process of the fish in 13 h with 20.1% moisture reduction. The temperature of the smoking chamber varied from 70 °C to 108 °C and the internal fish temperature during the cookin... [more]

Activated carbon (AC) has been extensively utilized as an adsorbent over the past few decades. AC has widespread applications, including the removal of different contaminants from water and wastewater, and it is also being used in capacitors, battery electrodes, catalytic supports, and gas storage materials because of its specific characteristics e.g., high surface area with electrical properties. The production of AC from naturally occurring precursors (e.g., coal, biomass, coconut shell, sugarcane bagasse, and so on) is highly interesting in terms of the material applications in chemistry; however, recently much focus has been placed on the use of agricultural wastes (e.g., rice husk) to produce AC. Rice husk (RH) is an abundant as well as cheap material which can be converted into AC for various applications. Various pollutants such as textile dyes, organic contaminants, inorganic anions, pesticides, and heavy metals can be effectively removed by RH-derived AC. In addition, RH-deriv... [more]

The Aquilaria malaccensis species of the genus Aquilaria is an abundant source of agarwood resin and many bioactive phytochemicals. Recent data regarding the chemical constituents and biological activities of Aquilaria leaves led us to attempt to qualitatively profile the metabolites of Aquilaria malaccensis leaves from a healthy, noninoculated tree through phytochemical screening, GC-MS, and LC/Q-TOF-MS. The present work is also the first to report the antilipoxygenase activity of A. malaccensis leaves from healthy noninoculated tree and investigate its toxicity on oral mucosal cells. A total of 53 compounds were tentatively identified in the extract, some of which have been described in literature as exhibiting anti-inflammatory activity. A number of compounds were identified for the first time in the extract of A. malaccensis leaf, including quercetin, quercetin-O-hexoside, kaempferol-O-dirhamnoside, isorhamnetin-O-hexoside, syringetin-O-hexoside, myricetin, tetrahydroxyflavanone, h... [more]

Mathematical optimization is the selection of the best element in a set with respect to a given criterion [...]

In this study, oxidizing roasting, segregation roasting, and magnetic separation are used to extract cobalt and iron from refractory Co-bearing sulfur concentrate. The Co-bearing sulfur concentrate containing 0.68% Co, 33.26% Fe, and 36.58% S was obtained from V-Ti magnetite in the Panxi area of China by flotation. Cobalt pyrite and linneite were the Co-bearing minerals, and the gangue minerals were mica, chlorite, feldspar, and calcite in Co-bearing sulfur concentrate. The results show that cobalt is transformed from Co-pyrite and linneite to a Co2FeO4-dominated new cobalt mineral phase, and iron is transformed from pyrite to Fe2O3 and an Fe3O4-dominated new iron mineral phase after oxidizing roasting. Cobalt changed from CoFe2O4 to a new cobalt mineral phase dominated by [Co] Fe solid solution, and iron changed from Fe2O3 to a new iron mineral phase dominated by metal Fe and Fe3O4 after segregation roasting. Cobalt concentrate with a cobalt grade of 15.15%, iron content of 71.22%, an... [more]

Lactic acid is an important chemical with numerous commercial applications that can be fermentatively produced from biological feedstocks. Producing lactic acid from corn grain could complement the use of already existing infrastructure for corn grain-based ethanol production with a higher value product. The objective of this study was to evaluate the techno-economic feasibility of producing 100,000 metric tons (t) of lactic acid annually from corn grain in a biorefinery. The study estimated the resources (equipment, raw materials, energy, and labor) requirements and costs to produce lactic acid from bacteria, fungi and yeast-based fermentation pathways. Lactic acid production costs were $1181, $1251 and $844, for bacteria, fungi and yeast, respectively. Genetically engineered yeast strains capable of producing lactic acid at low pH support significantly cheaper processes because they do not require simultaneous neutralization and recovery of lactic acid, resulting in lower requirement... [more]

In large scale ships, the most used controllers for the steam/water loop are still the proportional-integral-derivative (PID) controllers. However, the tuning rules for the PID parameters are based on empirical knowledge and the performance for the loops is not satisfying. In order to improve the control performance of the steam/water loop, the application of a recently developed PID autotuning method is studied. Firstly, a ‘forbidden region’ on the Nyquist plane can be obtained based on user-defined performance requirements such as robustness or gain margin and phase margin. Secondly, the dynamic of the system can be obtained with a sine test around the operation point. Finally, the PID controller’s parameters can be obtained by locating the frequency response of the controlled system at the edge of the ‘forbidden region’. To verify the effectiveness of the new PID autotuning method, comparisons are presented with other PID autotuning methods, as well as the model predictive control.... [more]

There had been a paradigm shift in tissue engineering studies over the past decades. Of which, part of the hype in such studies was based on exploring for novel biomaterials to enhance regeneration. Strontium ions have been reported by others to have a unique effect on osteogenesis. Both in vitro and in vivo studies had demonstrated that strontium ions were able to promote osteoblast growth, and yet at the same time, inhibit the formation of osteoclasts. Strontium is thus considered an important biomaterial in the field of bone tissue engineering. In this study, we developed a Strontium-calcium silicate scaffold using 3D printing technology and evaluated for its cellular proliferation capabilities by assessing for protein quantification and mineralization of Wharton’s Jelly mesenchymal stem cells. In addition, verapamil (an L-type of calcium channel blocker, CCB) was used to determine the mechanism of action of strontium ions. The results found that the relative cell proliferation rate... [more]

Polymer flooding is an effective enhanced oil recovery technology used to reduce the mobility ratio and improve sweep efficiency. A new polymer injection scheme is investigated that relies on the cyclical injection of low-salinity, low-concentration polymer slugs chased by high-salinity, high-concentration polymer slugs. The effectiveness of the process is a function of several reservoir and design parameters related to polymer type, concentration, salinity, and reservoir heterogeneity. We use reservoir simulations and design-of-experiments (DoE) to investigate the effectiveness of the proposed polymer injection scheme. We show how key objective functions, such as recovery factor and injectivity, are impacted by the reservoir and design parameters. In this study, simulations showed that the new slug-based process was always superior to the reference polymer injection scheme using the traditional continuous injection scheme. Our results show that the process is most effective when the p... [more]

Olive stones are an abundant lignocellulose material in the countries of the Mediterranean basin that could be transformed to bioethanol by biochemical pathways. In this work, olive stones were subjected to fractionation by means of a high-temperature dilute-acid pretreatment followed by enzymatic hydrolysis of the pretreated solids. The hydrolysates obtained in these steps were separately subjected to fermentation with the yeast Pachysolen tannophilus ATCC 32691. Response surface methodology with two independent variables (temperature and reaction time) was applied for optimizing D-xylose production from the raw material by dilute acid pretreatment with 0.01 M sulfuric acid. The highest D-xylose yield in the liquid fraction was obtained in the pretreatment at 201 °C for 5.2 min. The inclusion of a detoxification step of the acid prehydrolysate, by vacuum distillation, allowed the fermentation of the sugars into ethanol and xylitol. The enzymatic hydrolysis of the pretreated solids was... [more]

Magnesium silicate hydrate (M−S−H) cement, formed by reacting MgO, SiO2, and H2O, was used to encapsulate strontium (Sr) radionuclide. Samples were prepared using light-burned magnesium oxide and silica fume, with sodium hexametaphosphate added to the mix water as a dispersant. The performance of the materials formed was evaluated by leach testing and the microstructure of the samples was also characterized. The stabilizing/solidifying effect on Sr radionuclide in the MgO−SiO2−H2O system with low alkalinity is demonstrated in the study. The leaching rate in a standard 42-day test was 2.53 × 10−4 cm/d, and the cumulative 42-day leaching fraction was 0.06 cm. This meets the relevant national standard performance for leaching requirements. Sr2+ was effectively incorporated into the M−S−H hydration products and new phase formation resulted in low Sr leaching being observed.

At present, some achievements have been made in the research on the energy management of microgrid operation. However, the research is mainly on the operation of grid-connected microgrid, while the research on the energy management of islanded microgrid is still relatively few. Frequency is one of the characteristics that affects the reliability and power quality of the microgrid. The essence of controlling frequency stability is to maintain source-load balance and redistribution of active power. Therefore, this paper proposes a frequency control strategy based on dynamically cutting machine to reduce load by analyzing the use priority of different distributed power supply and the division of load importance degree, and combining the influence degree of different frequency variation range on microgrid. To coordinate and control distributed power supply, energy storage device, and load in different frequency change areas, this paper proposes different control strategies. The seed strate... [more]

Supersonic impinging jet flows always occur when aircrafts start short takeoff and vertical landing from the ground. Supersonic flows with residues produced by chemical reaction of fuel mixture have the potential of reducing aircraft performance and landing ground. The adverse flow conditions such as impinging force, high noise spectrum, and high shear stress always take place. Due to rare data on particle-gas impinging jet flows to date, three-dimensional numerical simulations were carried out to investigate supersonic impinging jet flows of particle-gas two phases in the present studies. A convergent sonic nozzle and a convergent-divergent supersonic nozzle were used to induce supersonic impinging jet flows. Discrete phase model (DPM), where interaction with continuous phase and two-way turbulence coupling model were considered, was used to simulate particle-gas flows. Effects of different particle diameter and Stokes number were investigated. Particle mass loading of 10% were consid... [more]

Considering the competitive and strongly regulated pharmaceutical industry, mathematical modeling and process systems engineering might be useful tools for implementing quality by design (QbD) and quality by control (QbC) strategies for low-cost but high-quality drugs. However, a crucial task in modeling (bio)pharmaceutical manufacturing processes is the reliable identification of model candidates from a set of various model hypotheses. To identify the best experimental design suitable for a reliable model selection and system identification is challenging for nonlinear (bio)pharmaceutical process models in general. This paper is the first to exploit differential flatness for model selection problems under uncertainty, and thus translates the model selection problem to advanced concepts of systems theory and controllability aspects, respectively. Here, the optimal controls for improved model selection trajectories are expressed analytically with low computational costs. We further demo... [more]

Hydraulic fracturing is a significant technique in petroleum engineering to enhance the production of shale gas or shale oil reservoir. The process of hydraulic fracturing is extremely complicated, referring to the deformation of solid formation, fluid flowing in the crack channel, and coupling the solid with fluid. Simulation of hydraulic fracturing and understanding the course of the mechanism is still a challenging task. In this study, two hydraulic fracturing models, including the Khristianovic−Geertsma−de Klerk (KGD) problem and the hydraulic fracture (HF) intersection with the natural fracture (NF), based on the zero thickness pore pressure cohesive zone (PPCZ) element with contact friction is established. The element can be embedded into the edges of other elements to simulate the fracture initiation and propagation. However, the mesh type of the elements near the PPCZ element has influences on the accuracy and propagation profile. Three common types of mesh, triangle mesh, quad... [more]

The production of organic acids by biotechnological processes has experienced a notable impulse with the advent of first and second generation biorefineries and the need of searching for renewable and sustainable feedstock, such as biomass. Fumaric acid is a promising biomonomer for polyamide production and a well-known acidulant and preservative in food and feed industries. Malic acid is a well-known food acidulant with a high market share. The biotechnological Fumaric and Malic acid production via fungi of the Rhizopus genus is being explored nowadays as a process for the valorization of food and food-related waste to obtain food ingredients and key platform chemicals of the so-called biochemical biorefinery. In this work, a preliminary study is performed to find reproducible conditions for the production of the acids by Rhizopus arrhizus NRRL 1526 by controlling fungi morphology and inoculum conditions. Afterwards, several production runs are performed to obtain biomass, glucose, an... [more]

Global warming is one of most severe environmental concerns that our planet is facing today. One of its causes is the previous generation of refrigerants that, upon release, remain in the atmosphere for longer periods and contribute towards global warming. This issue could potentially be solved by replacing the previous generation’s high global warming potential (GWP) refrigerants with environmentally friendly refrigerants. This scenario requires an analysis of new refrigerants for a comparison of the thermodynamic properties of the previously used refrigerants. In the present research, a numerical study was conducted to analyze the thermodynamic performance of specifically low GWP hydrofluoroolefens (HFO) refrigerants for an actual vapor compression refrigeration cycle (VCRC) with a constant degree of 3 K superheat. The output parameters included the refrigeration effect, compressor work input, the coefficient of performance (COP), and the volumetric refrigeration capacity (VRC), all... [more]

Reducing the mass of vehicles is an effective way to improve energy efficiency and mileage. Therefore, hot stamping is developed to manufacture lightweight materials used for vehicle production, such as magnesium and aluminum alloys. However, in comparison with traditional cold stamping, hot stamping is a high-energy-consumption process, because it requires heating sheet materials to a certain temperature before forming. Moreover, the process parameters of hot stamping considerably influence the product forming quality and energy consumption. In this work, the energy-economizing indices of hot stamping are established with multiobjective consideration of energy consumption and product forming quality to find a pathway by which to obtain optimal hot stamping process parameters. An energy consumption index is quantified by the developed models, and forming quality indices are calculated using a finite element model. Response surface models between the process parameters and energy-econom... [more]

Layout problems are an engineering task that heavily relies on project experience. During the design of a plant, various factors need to be considered. Most previous efforts on industrial layout design have focused on the arrangement of facilities in a plant. However, the area-wide layout was not thoroughly studied and the relationship between plant layout and area-wide layout was rarely mentioned. In this work, the key plant that has the greatest impact on the industrial area is figured out first, and then the coupling relationships between the key plant and the industrial area are studied by changing the occupied area and length-width ratio of the key plant. Both of them are achieved by changing the floor number. A hybrid algorithm involving the genetic algorithm (GA) and surplus rectangle fill algorithm (SRFA) is applied. Various constraints are considered to make the layout more reasonable and practical. In the case study, a refinery with 20 plants is studied and the catalytic crac... [more]

The process of homogenization of particulates is an indispensable part of many industrial processes, and, therefore, it is necessary to pay a special attention to this area and develop it. This paper deals with a complex study of homogenization of particulate matters in a rotary drum in terms of shape, size, and density of particles. In addition, the influence of operating parameters, such as drum filling capacity, rotational speed, and drum filling pattern are also investigated. Studies of reproducibility of discrete element method simulations, effects of rotary drum sizes or effects of drum volumetric filling to the mixture homogeneity index were also carried out. In general, the least satisfactory values of the homogeneity index resulted from the mixing of particles with different densities. The dominating factor of homogenization was the drum filling-up degree. The course of the homogeneity index in 140, 280, and 420 mm drums was very similar and after five revolutions of the drum,... [more]

Membranes, as the primary tool in membrane separation techniques, tend to suffer external deposition of pollutants and microorganisms depending on the nature of the treating solutions. Such issues are well recognized as biofouling and is identified as the major drawback of pressure-driven membrane processes due to the influence of the separation performance of such membrane-based technologies. Herein, the aim of this review paper is to elucidate and discuss new insights on the ongoing development works at facing the biofouling phenomenon in membranes. This paper also provides an overview of the main strategies proposed by “membranologists” to improve the fouling resistance in membranes. Special attention has been paid to the fundamentals on membrane fouling as well as the relevant results in the framework of mitigating the issue. By analyzing the literature data and state-of-the-art, the concluding remarks and future trends in the field are given as well.

To achieve the optimal operation of chemical processes in the presence of disturbances and uncertainty, a retrofit hierarchical architecture (HA) integrating real-time optimization (RTO) and control was proposed. The proposed architecture features two main components. The first is a fast extremum-seeking control (ESC) approach using transient measurements that is employed in the upper RTO layer. The fast ESC approach can effectively suppress the impact of plant-model mismatch and steady-state wait time. The second is a global self-optimizing control (SOC) scheme that is introduced to integrate the RTO and control layers. The proposed SOC scheme minimizes the global average loss based on the approximation of necessary conditions of optimality (NCO) over the entire operating region. A least-squares regression technique was adopted to select the controlled variables (CVs) as linear combinations of measurements. The proposed method does not require the second order derivative information,... [more]

Alkylate produced by catalyzed reaction of isobutane and olefin-rich streams is a desired component for gasoline blending. Fractionation of the alkylation reactor effluent is energy demanding due to the presence of close boiling point components and solutions cutting its energy intensity; expenses associated with this process are investigated intensely nowadays. This paper presents a novel conceptual design and techno-economic analysis of alkylation reaction effluent fractionation revamp to reach a cut in energy costs of the fractionation process without the need to revamp the rectification columns themselves, providing thus an alternative approach to a more sustainable alkylation process. Two cases are considered—A. additional steam turbine installation or B. combustion engine-driven heat pump-assisted rectification. Mathematical modeling of the considered system and its revamp is applied using the “frozen technology” approach. Real system operation features and seasonal variations ar... [more]

The principle of sustainable development is becoming more and more prominent in various schools, and the eco-campus in rural areas often has more room for display. The identification and assessment of cost-effective biomass resources appropriate for recycling represent an opportunity that may significantly improve the comprehensive efficiency of an eco-campus system, resulting in remarkable investment savings, pollution reduction, as well as reducing energy consumption and resources waste. The economic feasibility of two biogas-linked rural campus systems (Fanjiazhai Middle School, FJZ and Xidazhai Middle School, XDZ, Yangling, China), as well as their key technologies, is investigated, the two systems respectively represent two biobased agricultural production modes. It is found that the initial investment, operating investment, and total revenue of FJZ system is 1.37 times, 2.39 times, and 1.71 times of XDZ system respectively, thus indicating that FJZ campus is proved to be a “large... [more]