As the utilization of zeolites has become more frequent in the dry reforming of methane (DRM) reaction, more systematic studies are required to evaluate properly the influence of zeolites’ composition and framework type on the performance. Therefore, in this work, a step-by-step study was performed with the aim of analyzing the effects of Ni loading (5, 10 or 15 wt.% over USY(3) zeolite), Si/Al ratio (3, 15 or 38 on USY zeolites with 15 wt.% Ni) and framework type (USY, BEA, ZSM-5 or MOR for 15 wt.% Ni and Si/Al ratios of ≈40) on catalysts’ properties and performances. Increasing Ni loadings enhanced CH4 and CO2 conversions even though the catalysts’ stability was decreasing over the time. The variation of the Si/Al ratio on USY and the use of different zeolites had also a remarkable impact on the catalytic performance. For instance, at 500−600 °C reaction temperatures, the catalysts with higher basicity and reducibility exhibited the best results. However, when the temperature was fur... [more]

The foundation of the national economy is agriculture, agricultural modernization is the symbol of national modernization and agricultural mechanization is an important symbol of agricultural modernization. In this paper, the authors conducted an analysis of the agricultural mechanization levels of 31 provincial areas in China. In order to assess the agricultural mechanization levels of the provincial areas in China as accurately as possible, the authors adopted indicators in the year 2005, the year 2010 and the year 2015, and used the comparative static analysis method to observe the dynamic changes in the data over the three years. Eight items, including total agricultural mechanization power/grain output (10 million watts/10 k tons), number of large and medium-sized tractors/grain output (pcs/10 k tons), tractor plowing area/grain output (k hectares/10 k tons), total input of agricultural mechanization business operation/grain output (million yuan/10 k tons), total income of agricul... [more]

Water-based propolis extracts usually contain up to 10-fold lower quantities of active ingredients due to poor solubility in water of propolis bioactive compounds when compared with ethanol-based extracts. Since ethanol-based extracts are of limited use, water-based extracts are preferred nowadays. The application of alternative extraction techniques should be evaluated to improve extraction efficiency. Aqueous propolis extracts were prepared using purified water and propylene glycol, 2-hydroxypropyl-beta-cyclodextrin and sodium bicarbonate aqueous solutions. A microwave-assisted extraction method was applied in cycles. The total concentration of hydroxycinnamic acids in aqueous propolis extract produced by four extraction cycles was determined to be 1502.1 ± 130.1 μg/mL and 20% propylene glycol, 10% 2-hydroxypropyl-beta-cyclodextrin and 5% sodium bicarbonate aqueous solutions, increasing the total concentration of hydroxycinnamic acids by 1.6, 1.7 and 1.9-fold, respectively. An applic... [more]

Olaparib (OLP) is an orally active poly (ADP-ribose) polymerase enzyme inhibitor, approved for treatment for the metastatic stage of prostate, pancreatic, breast and ovarian cancer. Due to its low bioavailability, an increase in dose and frequency is required to achieve therapeutic benefits, which also results in associated toxicity in patients. In the current study, OLP-loaded poly (d,l-lactide-co-glycolide) (PLGA) nanoparticles (NPs) (OLP-PLGA NPs) and a coating of OLP-PLGA NPs with chitosan (CS) (OLP-CS-PLGA NPs) were prepared successfully in order to improve the dissolution rate and bioavailability. The developed OLP-PLGA NPs were evaluated for hydrodynamic particle size (392 ± 5.3 nm), PDI (0.360 ± 0.03), ZP (−26.9 ± 2.1 mV), EE (71.39 ± 5.5%) and DL (14.86 ± 1.4%), and OLP-CS-PLGA NPs, hydrodynamic particle size (622 ± 9.5 nm), PDI (0.321 ± 0.02), ZP (+36.0 ± 1.7 mV), EE (84.78 ± 6.3%) and DL (11.05 ± 2.6%). The in vitro release profile of both developed NPs showed a sustained re... [more]

The structure and dynamics of a reciprocating pump liquid end affect the volumetric efficiency and net positive suction head. To match the kinematics with theoretical parameters, reciprocating pump valve motion and flow visualization tests and computational fluid dynamics (CFD) analyses were performed on a wing-guided bevel discharge valve in a horizontal quintuple single-acting reciprocating pump. The valve motion test results showed that the maximum pump valve displacement and the pump valve opening and closing durations were approximately 8.3 mm, 29 ms, and 38 ms, respectively. The corresponding flow visualization test results were 11.4 mm, 9.5 ms, and 35.5 ms. The valve closing durations obtained from the valve motion and flow visualization tests are approximately twice as high as the U-Adolph prediction. The maximum displacement obtained from the valve motion test is consistent with the U-Adolph prediction. Three-dimensional CFD analyses were performed to investigate the flow stat... [more]

This paper presents a Sigmoid-like event-triggered scheme (Sigmoid-like ETS) for security cruise control systems (CCSs) under stochastic false data injection (FDI) attacks. In order to improve the sensitivity of the ETS, a Sigmoid-like function is first proposed to adjust the event-triggered threshold, dynamically. In what follows, by considering a class of stochastic FDI attacks which obey Bernoulli distribution, the Sigmoid-like event-triggered security control strategy is proposed to ensure both the security and resource saving of the CCSs. Thus, a sufficient stability and stabilization criterion is well derived to present the co-design of an H∞ control and event-triggered parameter. Finally, some simulation experiments are conducted to verify the effectiveness of the proposed Sigmoid-like event-triggered security cruise control for networked vehicles.

With the application of complex fracturing and other complex technologies, external extrusion has become the main cause of casing damage, which makes non-API high-extrusion-resistant casing continuously used in unconventional oil and gas resources exploitation. Due to the strong sensitivity of string ovality, uneven wall thickness, residual stress, and other factors to high anti-collapse casing, the API formula has a big error in predicting the anti-collapse strength of high anti-collapse casing. Therefore, Bayesian regularization artificial neural network (BRANN) is used to predict the external collapse strength of high anti-collapse casing. By collecting full-scale physical data, including initial defect data, geometric size, mechanical parameters, etc., after data preprocessing, the casing collapse strength data set is established for model training and blind measurement. Under the classical three-layer neural network, the Bayesian regularization algorithm is used for training. Thro... [more]

The effect of the partition coefficient on the simulation of the operation of a biotrickling filter treating a mixture of sulfur compounds was analyzed to evaluate the pertinence of using Henry’s law in determining its removal capacity. The analysis consisted of the simulation of a biotrickling filter that bio-oxides hydrogen sulfide (H2S), dimethyl sulfide (DMS), methyl mercaptan (MM) and dimethyl disulfide (DMDS) using different types of models for determining the partition coefficient: Henry’s law for pure water, Henry’s law adjusted from experimental data, a mixed model (Extended UNIQUAC) and a semi-empirical model of two-parameters. The simulations were compared with experimental data. It was observed that Henry’s law for pure water could produce significant deviations from empirical data due to the liquid phase not being pure water. The two-parameter model better fits with similar results compared to the extended UNIQUAC model, with a lower calculation cost and necessary paramete... [more]

Beta-carotene (BC) is a precursor of vitamin A and an excellent antioxidant. It protects the vascular system. Vascular dementia (VaD) is one of the aging disorders causing memory dysfunction. The available medicines for the management of VaD are limited. The present study aimed to evaluate the ameliorative effect of BC in streptozotocin (STZ)-induced diabetic VaD in rats. Diabetic VaD was induced through the administration of nicotinamide (NA, 50 mg/kg; i.p.) and STZ (50 mg/kg; i.p.). The test compound BC (50 and 100 mg/kg; p.o.) and reference compound donepezil (1 mg/kg; p.o.) were administered for 15 consecutive days. Cognitive changes were assessed by transfer latency (TL) using the elevated plus maze (EPM) test. The changes in acetylcholinesterase (AChE) activity were estimated in the septohippocampal system of rat brains. The administration of STZ caused significant changes in cognitive functions (increased TL) as compared to the normal group. BC ameliorated the anxiety-related co... [more]

For Francis pump turbines, the pressure pulsation characteristics of the draft tube are some of the key concerns during the operation of the units. The pressure pulsation characteristics of the draft tube are directly related to the draft tube spiral cavitating vortex rope. In this paper, the velocity distribution in the draft tube of a Francis pump turbine is tested by means of laser Doppler velocimetry. The velocity pulsation was found to be directly related to the pressure pulsation, while the velocity pulsation was also influenced by the cavitation coefficient. The main frequency of the velocity pulsation was close to the main frequency of the pressure pulsation and became larger as the cavitation factor increased.

The relaxation of a rigid particle suspended in a one-dimensional oscillating flow is calculated according to different drag models and the results are compared. Conditions are derived under which relaxation can be neglected or drag models can be substituted by simpler ones. This investigation is conducted analytically and graphically via the plane defined by the Reynolds number and amplitude parameter. This work matches various, mostly analytic drag models together to consider simple particle relaxation with a few, broad range input parameters and cover large parts of the plane spanned by Reynolds number and amplitude parameter.

Pore structure is the key factor affecting reservoir accumulation and enrichment behavior. Due to the complex mineral components and pore structure of shale oil reservoirs and strong heterogeneity, it is necessary to explore the micro-pore structure characteristics of inter-salt shale. In this study, in order to qualitatively and quantitatively analyze the pore structure of inter-salt shale reservoirs, as well as evaluate the mineral composition and its spatial distribution characteristics, three shale samples from the 10th cyclothem of the Eq3 (Eq34−10 cyclothem) inter-salt shale were selected to acquire 2D and 3D grayscale images by modular automated processing system (MAPS) and X-ray micro-computed tomography (Micro-CT), respectively. The color map of the inlaid characteristics of mineral aggregates was established by Quantitative Evaluation of Minerals by Scanning Electron Microscopy (QEMSCAN), and different mineral types in the grayscale image were determined. After that, the digi... [more]

Liquid fertilizers are mainly applied by spraying liquid fertilizer on the surface of crop leaves and by deep openings between rows. The first causes considerable environmental pollution, and the second can easily cause to damage the root system of crops. In this study, corn crops were taken as the study object and an efficient deep-hole application method for liquid fertilizer based on alternate drilling was proposed. The needle body is driven by the spur gear wheel system in a caving mechanism to puncture holes alternately in a vertical posture and high-speed punctures are implemented with less disturbance to the soil. The cylindrical hollow cam of the mechanism is controlled so that the fertilizer needle sprays fertilizer when injected into soil and stops injecting when pulled out of the soil. Based on the bench test, fertilizer injecting performance and energy saving performance of the differential two-way fertilizer supply distribution device were analyzed and the head loss for en... [more]

Crystal blockages of tunnel drainage systems severely undermine the tunnel lining structure and operation safety. In order to reduce the risk of crystal blockages of tunnel drainage systems, the distribution of highway tunnel defects was identified through a field survey, indoor test, and literature analysis, and an optimization method of tunnel drainage structures was proposed. The research suggested the following: (1) Lining water leakage and construction joint water leakage were the most common defects in the tunnel drainage system of Renhua−Xinfeng Expressway and Yingde−Huaiji Expressway in Guangdong Province, accounting for 60% and 32% of total defects, respectively. The number of defects that occurred in the drainage system of the tunnel was larger in the granite formation, with the number of road seepage and inspection chamber crystallization incidents reaching 2.5/km and 2.8/km, respectively. (2) The groundwater was mainly alkaline with a pH value of 8~12, Ca2+ (107 mg/L) was t... [more]

Retinopathy is one of the most common complications of diabetes mellitus. Diabetic retinopathy (DR) occurs due to microvascular damage in retinal tissues provoked by high blood sugar levels. The available drugs for DR are limited. Astaxanthin (AST) has anti-hypertensive, anti-obesity, and anti-diabetic properties. However, the therapeutic effect of AST on DR remains elusive. The present study is designed to investigate the effects of AST on DR via inhibition of neuron-specific enolase (NSE) activity. DR was induced by the administration of streptozotocin (STZ, 35 mg/kg: intraperitoneal; and 20 μL of STZ: intravitreal) in mice. AST (10 and 20 mg/kg) was administered orally (p.o.) for 21 days. The DR associated visual changes were assessed at different time intervals via optokinetic motor response (OMR) and penta-maze (PM) tests. Blood glucose level as well as retinal catalase, lactate dehydrogenase (LDH), & neuron-specific enolase (NSE) were estimated. The reference drug i.e., dexametha... [more]

Multiphase pumps are used as an important tool for natural gas hydrate extraction owing to their excellent gas−liquid mixing and transport properties. This paper proposes an adaptive response surface-based integrated optimization design method. A model pump is designed based on the axial flow pump design theory. The model pump is numerically simulated and analyzed to obtain its performance parameters. Then the structural and performance parameters of the pump are parameterized to establish a closed-loop input−output system. Based on this closed-loop system, a sensitivity analysis is performed on the structural parameters of the impeller and guide vane, and the parameters that affect the performance of the gas−liquid hybrid pump the most are derived. The Sparse Grid method was introduced to design the experiment and construct the approximate model. The structural parameters of the impeller and guide vane are used as design variables to optimize the pressure increment and efficiency of t... [more]

The intensive production of fossil fuels has led to serious polycyclic aromatic hydrocarbon (PAH) contamination in water and soil environments (as PAHs are typical types of emerging contaminants). Bio-Fenton, an alternative to Fenton oxidation, which generates hydrogen peroxide at a nearly neutral pH condition, could ideally work as a pretreatment to recalcitrant organics, which could be combined with the subsequent biological treatment without any need for pH adjustment. The present study investigated the performance of a Bio-Fenton-assisted biological process for mineralization of three typical types of PAHs. The hydrogen peroxide production, PAH removal, overall organic mineralization, and microbial community structure were comprehensively studied. The results showed that the combined process could achieve efficient chemical oxygen demand (COD) removal (88.1%) of mixed PAHs as compared to activated sludge (33.1%), where individual PAH removal efficiencies of 99.6%, 83.8%, and 91.3%... [more]

In this paper, a three-dimensional model of a high-temperature anion-exchange membrane fuel cell (HT-AEMFC) operating at 110 °C is presented. All major transport phenomena along with the electrochemical reactions that occur in the cell are modeled. Since the water is exclusively in the form of steam and there is no phase transition to deal with in the cell, the water management is greatly simplified. The cell performance under various current loads is evaluated, and the results are validated against the experimental data. The cell performance is examined across a range of operating conditions, including cell temperature, inlet flow rate, and inlet relative humidity (RH). The critical link between the local distributions of species and local current densities along the channels is identified. The distribution of reactants continuously drops in the gas flow direction along the flow channels, causing a non-uniform local current distribution that becomes more pronounced at high current loa... [more]

The prevalence of gastric ulcers has increased in recent years, mainly because of non-steroidal anti-inflammatory drug utilization. Therefore, the current study investigates the gastroprotective effect of p-Cymene on absolute ethanol-induced acute gastric mucosal hemorrhagic lesions in rats. Thirty Sprague Dawley rats were randomly separated into five groups: normal control, ulcer control, reference, and two experimental groups. The normal and ulcer control groups were orally fed with 0.5% carboxymethylcellulose (CMC). The reference group was fed orally with 20 mg/kg omeprazole. The experimental groups were fed with 30 mg/kg and 60 mg/kg p-Cymene, respectively. After one hour, the normal group was fed with 0.5% CMC, and groups 2−5 were given absolute alcohol. After another hour all rats were sacrificed. The ulcer control group showed severe superficial hemorrhagic gastric mucosal lesions with decreased gastric mucus secretion and pH of gastric content. p-Cymene significantly reduced et... [more]

Welding is widely used to manufacture and repair steel structures such as piping and pressure vessels. Welding induces deformation and residual stress, which influences the mechanical performance of the structural members. Noting patch welding, which is applied to repair steel structures, a series of patch welding experiments and numerical analyses were carried out. The features of out-of-plane deformation and residual stress by patch welding were examined by changing the patch size. The out-of-plane deformation showed different modes in the patch joints. The magnitude of the out-of-plane deformation depended on the patch size. The tensile residual stress at the weld toe increased with the enlargement of the patch size. The costs for the different sizes of patch welding were estimated for choosing the patch size reasonably. The patch size should be determined by considering the mechanical influences of welding and the economic viewpoints of the welding process.

An electrochemical method for the determination of the catalytic activity of L-asparaginase (ASNase) from Erwinia carotovora was proposed. Our approach is based on the electrooxidation of amino acids from L-asparaginase polypeptide backbones. The electrochemical behavior of ASNase on electrodes obtained by screen-printing modified with single-wall carbon nanotubes (SPE/SWCNTs) as sensing elements demonstrated a broad oxidation peak at 0.5−0.6 V centered at 0.531 ± 0.010 V. We have shown that in the presence of the substrate L-asparagine, the oxidation current of the enzyme was reduced in a concentration-dependent manner. The specificity of electrochemical analysis was confirmed in experiments with glycine, an amino acid with no substrate activity on ASNase and does not reduce the oxidation peak of L-asparaginase. The addition of glycine did not significantly influence the amplitude of the oxidation current. The innovative aspects of the proposed electrochemical sensor are the direct mo... [more]

Due to its high hardness and high transmittance, ultra-white glass has a strong application prospect in the fields of optoelectronics industry and experimental instruments. However, because of its brittleness, it was still a difficult problem in the machining industry. Surface modification provides a basic research idea for ultra-white glass microstructure processing. An effective method to obtain surface modified area on ultra-white glass was presented. The modified zone on the surface of ultra-white glass was induced by the technique of coating and femtosecond laser-assisted chemical etching. The method combines vacuum coating with femtosecond laser irradiation. Next, the modified glass was processed with highly selective potassium hydroxide solution. In order to control the surface size more efficiently, the optimization experiment of laser parameters and chemical parameters on the machining process was carried out. The experimental results show that the method made the surface modi... [more]

Countries all over the world are making their contribution to the common goal of energy saving and emission reduction. Solar energy is gaining more attention as a renewable energy source. Polysilicon is an important raw material for solar panels and the production of polysilicon is a vital part of the photovoltaic industry. Polysilicon production is a typical process industry enterprise, and its production process is continuous and highly energy intensive. Therefore, it is necessary to forecast and analyze the consumption of polysilicon production plants. To address the problem that it is difficult to predict future consumption based on historical data alone due to the time-series, massive, nonlinear, and complex nature of data in polysilicon workshops. This study proposes a combined workshop energy consumption prediction model based on Bayesian estimation of time-series decomposition and convolutional neural network (TSD-CNN). The method uses a time-series decomposition method to mode... [more]

Hydrokinetic turbine deployment in inland water reticulation systems such as irrigation canals has potential for future renewable energy development. Although research and development analysing the hydrodynamic effects of these turbines in tidal applications has been carried out, inland canal system applications with spatial constraints leading to possible blockage and backwater effects resulting from turbine deployment have not been considered. Some attempts have been made to develop backwater models, but these were site-specific and performed under constant operational conditions. Therefore, the aim of this work was to develop a generic and simplified method for calculating the backwater effect of HK turbines in inland systems. An analytical backwater approximation based on assumptions of performance metrics and inflow conditions was tested using validated computational fluid dynamics (CFD) models. For detailed prediction of the turbine effect on the flow field, CFD models based on R... [more]

In the last decade, the green synthesis of nanoparticles has had a prominent role in scientific research for industrial and biomedical applications. In this current study, silver nitrate (AgNO3) was reduced and stabilized with an aqueous extract of Thelypteris glandulosolanosa (Raqui-raqui), forming silver nanoparticles (AgNPs-RR). UV-vis spectrophotometry, dynamic light scattering (DLS), and scanning transmission electron microscopy (STEM) were utilized to analyze the structures of AgNPs-RR. The results from this analysis showed a characteristic peak at 420 nm and a mean hydrodynamic size equal to 39.16 nm, while the STEM revealed a size distribution of 6.64−51.00 nm with an average diameter of 31.45 nm. Cellular cytotoxicity assays using MCF-7 (ATCC® HTB-22™, mammary gland breast), A549 (ATCC® CCL-185, lung epithelial carcinoma), and L929 (ATCC® CCL-1, subcutaneous connective tissue of Mus musculus) demonstrated over 42.70% of MCF-7, 59.24% of A549, and 8.80% of L929 cells had cell d... [more]