LAPSE:2026.1321
Model
LAPSE:2026.1321
A Stochastic c-Myc Regulated Model of CD8+ T Cell Dynamics and Lineage Tracking
October 3, 2026
Abstract
This is the MATLAB source code for a stochastic agent-based model of CD8+ T cell responses following vaccination. The model simulates T cell activation, proliferation, contraction, and differentiation into effector and memory populations. Cell division is regulated by intracellular c-Myc dynamics, and the model includes asymmetric inheritance of c-Myc between daughter cells. A lineage tracking module is also added to follow the descendants and division histories of individual simulated T cell families.
Keywords
effector cell, Fate mapping, Memory cell, Modelling, T cell, Vaccine
Subject
Suggested Citation
Seyyedizadeh SF, Christian DA, Adams II TA. A Stochastic c-Myc Regulated Model of CD8+ T Cell Dynamics and Lineage Tracking. (2026). LAPSE:2026.1321
Author Affiliations
Seyyedizadeh SF: McMaster University [ORCID]
Christian DA: University of Pennsylvania [ORCID]
Adams II TA*: Norwegian University of Science and Technology [ORCID]
* Corresponding Author
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Publication Date
2026-10-02
Version Comments
Original Submission
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Oct 3, 2026
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[v1] (Original Submission)
Oct 3, 2026
 
Verified by curator on
Oct 8, 2026
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v1
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URL Here
https://psecommunity.org/LAPSE:2026.1321
 
Record Owner
Seyedeh Fatemeh Seyyedizadeh
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