LAPSE:2026.1321
Model

LAPSE:2026.1321
A Stochastic c-Myc Regulated Model of CD8+ T Cell Dynamics and Lineage Tracking
October 3, 2026
Abstract
This is the MATLAB source code for a stochastic agent-based model of CD8+ T cell responses following vaccination. The model simulates T cell activation, proliferation, contraction, and differentiation into effector and memory populations. Cell division is regulated by intracellular c-Myc dynamics, and the model includes asymmetric inheritance of c-Myc between daughter cells. A lineage tracking module is also added to follow the descendants and division histories of individual simulated T cell families.
This is the MATLAB source code for a stochastic agent-based model of CD8+ T cell responses following vaccination. The model simulates T cell activation, proliferation, contraction, and differentiation into effector and memory populations. Cell division is regulated by intracellular c-Myc dynamics, and the model includes asymmetric inheritance of c-Myc between daughter cells. A lineage tracking module is also added to follow the descendants and division histories of individual simulated T cell families.
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Keywords
effector cell, Fate mapping, Memory cell, Modelling, T cell, Vaccine
Subject
Suggested Citation
Seyyedizadeh SF, Christian DA, Adams II TA. A Stochastic c-Myc Regulated Model of CD8+ T Cell Dynamics and Lineage Tracking. (2026). LAPSE:2026.1321
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Publication Date
2026-10-02
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Original Submission
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[v1] (Original Submission)
Oct 3, 2026
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Oct 8, 2026
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v1
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https://psecommunity.org/LAPSE:2026.1321
Record Owner
Seyedeh Fatemeh Seyyedizadeh
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