LAPSE:2025.0586v3
Model

LAPSE:2025.0586v3
The SATvac model of CD8+ T cell expansion and contraction phases considering memory and effector cell differentiation
August 15, 2025. Originally submitted on August 13, 2025
Abstract
This is the MATLAB source code for the SATvac (Stochastic Agent-based T-cell Vaccination) model, a stochastic agent-based framework for simulating CD8+ T cell dynamics following vaccination. This model captures main immune response phases including activation, expansion, and contraction. It also tracks T cell differentiation into effector and memory cell types and explains the variability observed in immune responses by modeling stochasticity at the single cell level.
This is the MATLAB source code for the SATvac (Stochastic Agent-based T-cell Vaccination) model, a stochastic agent-based framework for simulating CD8+ T cell dynamics following vaccination. This model captures main immune response phases including activation, expansion, and contraction. It also tracks T cell differentiation into effector and memory cell types and explains the variability observed in immune responses by modeling stochasticity at the single cell level.
Record ID
Keywords
Computational Biology, Effector cell, Memory cell, Modelling, Stochastic Modelling, T cell, Vaccine
Subject
Suggested Citation
Seyyedizadeh SF, Christian DA, Adams II TA. The SATvac model of CD8+ T cell expansion and contraction phases considering memory and effector cell differentiation. (2025). LAPSE:2025.0586v3
Author Affiliations
Seyyedizadeh SF: McMaster University [ORCID]
Christian DA: University of Pennsylvania [ORCID] [Google Scholar]
Adams II TA*: Norwegian University of Science and Technology [ORCID] [Google Scholar]
* Corresponding Author
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Christian DA: University of Pennsylvania [ORCID] [Google Scholar]
Adams II TA*: Norwegian University of Science and Technology [ORCID] [Google Scholar]
* Corresponding Author
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Year
2025
Publication Date
2025-08-14
Version Comments
Revision of Version 2
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Version History
[v3] (Revision of Version 2)
Aug 15, 2025
[v2] (Revision of Version 1)
Aug 14, 2025
[v1] (Original Submission)
Aug 13, 2025
Verified by curator on
Aug 13, 2025
This Version Number
v3
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URL Here
https://psecommunity.org/LAPSE:2025.0586v3
Record Owner
Seyedeh Fatemeh Seyyedizadeh