In order to improve the recovery efficiency of the Jimusaer tight reservoir in Xinjiang, the nanometer oil displacement agent system suitable for the Jimusaer reservoir was used. In view of the low permeability, high formation temperature, and high salinity characteristics of the prepared water in the Jimusaer tight conglomerate reservoir in Xinjiang, the performance of the nanometer oil displacement agent affecting oil recovery was studied; the study considered interfacial tension, temperature resistance, wetting performance, static oil washing efficiency, and long-term stability. Nanometer oil displacement agent No. 4 had the lowest interfacial tension and could reach the order of 10−1 mN∙m−1; it had excellent temperature resistance and the best static oil washing efficiency and stability. Nano-oil displacement agent No. 2 had the best emulsification performance and wettability and also had good stability. By studying the performance and final oil displacement effect of the nano-oil displacement agent, it was found that the key factor affecting the oil displacement effect of this reservoir was the interfacial activity of the nano-oil displacement agent. When the interfacial tension was lower, it produced strong dialysis for oil displacement. The emulsification effect has a negative effect on low-permeability reservoirs, mainly because the fluid produces strong emulsification in low-permeability reservoirs; thus, it can easily block the formation and cause high pressure. An excessive or small contact angle is not conducive to oil displacement. An excessive contact angle means strong hydrophilicity, which can cause a strong Jamin effect in oil-friendly formations. If the contact angle is too small, it has strong lipophilicity and can lead to poor solubility in water. Nano-oil displacement agent No. 4 had the best oil displacement effect, with an oil recovery increase of 7.35%, followed by nanometer oil displacement agent No. 1, with an oil recovery increase of 5.70%. Based on all the performance results, nanometer oil displacement agent No. 4 was more suitable as the oil displacement agent and can be used to enhance oil recovery in the Jimusaer reservoir. This study has laid a foundation for the chemical flooding development of shale oil in the Xinjiang oilfield.