The present paper proposes a new methodology to aid the electrification process of local public transport (LPT). In more detail, real drive cycles of traditional buses currently in use are evaluated together with other data to simulate the consumption of equivalent e-buses (electric buses) with similar characteristics. The results are then used in order to design the best charging infrastructure. The proposed methodology is applied to the case study of Algeciras Bay, where a specific line of LPT is considered. Real measurements are used as data for the simulation model, and the average consumption of an equivalent e-bus is obtained for different operating conditions. Based on these results, different sizes and locations for fast-charging infrastructure are proposed, and the size of the depot charging system is defined trying to maintain the current buses timetable. Finally, some future developments of the present work are presented by considering other bus lines that may benefit from the introduction of the defined charging systems.