This paper introduces a case study on the failure mechanism and support design of a roadway tunnel in the fault fracture zone of the 106 mining area in the Yuandian no.2 coal mine. Based on the on-site geological conditions (in-situ stress test, borehole television imaging, and lithological analysis), the failure mechanism of the roadway tunnel in the fault fracture zone was studied. The test results showed that the high tectonic stress, fractured rock, and poor lithology are the primary reasons for the roadway instability. According to the support principles of grouting reinforcement, pre-reinforced support, and rational support range, a new type of combined support technology was proposed, including advanced grouting, grouting bolts, and grouting anchor cables. A 100 m roadway section was selected for field testing using the new support scheme, and detailed deformation monitoring was performed. Monitoring results showed that the roadway deformation under the new support was significantly reduced. During the roadway excavation process, no roof collapse phenomenon occurred, and the safety of roadway excavation was ensured. This successful case provides an important reference for similar roadway projects in the fault fracture zone.