Greenhouse crops represent a significant productive sector of the agricultural system; one of the main problems to be addressed is indoor air conditioning to ensure thermal well-being of crops. This study focuses on the ventilation analysis of solar greenhouse with symmetrical flat pitched roof and single span located in a warm temperate climate. This work proposes the dynamic analysis of the greenhouse modeled in TRNsys, simultaneously considering different thermal phenomena three-dimensional (3D) shortwave and longwave radiative exchange, airflow exchanges, presence of lamps with their exact 3D position, ground and plant evapotranspiration, and convective heat transfer coefficients. Several air conditioning systems were analyzed, automatic window opening, controlled mechanical ventilation systems (CMV) and horizontal Earth-to-Air Heat Exchanger (EAHX) coupled with CMV, for different air volume changes per hour. In summer, the exploitation of the ground allows having excellent results with the EAHX system, reducing the temperature peaks of up to 5 °C compared to the use of CMV. In winter, it is interesting to note that, although the EAHX is not the solution that raises the temperature the most during the day, its use allows flattening the thermal wave more. In fact, the trend is almost constant during the day, raising the temperature during the first and last hours of the day.