Electrochemical low-cost sensors, suitable for the monitoring of different air quality parameters such as carbon monoxide or nitrogen dioxide levels, are viable tools for creating affordable handheld devices for short-term or dense air quality monitoring networks for long-term measurements and IoT applications. However, most devices that utilize such sensors are based on proprietary hardware and software and, therefore, do not offer users the ability to replace sensors or interact with the hardware, software, and data in a meaningful way. Initiatives that focus on an open framework for air quality monitoring, such as the AirSensEUR project, offer competitive open source alternatives. In this study, we examined the feasibility of the application of such devices. Five AirSensEUR units equipped with chemical sensors were placed next to a reference air quality measuring station in Vienna, Austria. During co-location, concentrations of 0.20 ± 0.06 ppm, 7.14 ± 8.66 ppb, and 17.58 ± 9.90 ppb were measured for CO, NO, and NO2, respectively. The process of evaluating the performance of the low-cost sensors was carried out and compared to similar studies. Data analysis was carried out with the help of the basic functions in MS Excel. We investigated the linear correlation between the sensor and reference data and thus calculated the coefficient of determination, the average and maximum residuals, and the correlation coefficient. Furthermore, we discuss sensor properties in regard to selectivity and long-term stability.