The blade wrap angle of impeller is an important structural parameter in the hydraulic design of open-design vortex pump. In this paper, taking a vortex pump with a cylindrical blade structure as the research object, two kinds of different blade wrap angle of vortex pump impellers are designed. The experiment and numerical simulation research is carried out, and the results of external characteristics and internal flow field are obtained under different flow rate. The results show that when ensuring that other main structural parameters remain unchanged, the efficiency and head of open-design vortex pump increase with the blade wrap angle decreases. In the case of blade wrap angle increasing, the length of rotating reflux back from lateral cavity to inlet is longer. For the same type of vortex pump, the length of rotating reflux to inlet decreases with the increase of flow rate. At the inlet area of impeller front face, there is an area where liquid flows back to the lateral cavity. The volute section shows that after passing through the impeller and lateral cavity, the liquid is discharged to the pump outlet with strong spiral strength. It is found that the blade wrap angle decreases and the shaft power increases, while the pump efficiency increases. The impeller blade wrap angle of vortex pump can be considered to select a smaller value.