LAPSE:2021.0334v1
Published Article
LAPSE:2021.0334v1
Pressurized Liquid Extraction of Cannabinoids from Hemp Processing Residues: Evaluation of the Influencing Variables
Sebastián Serna-Loaiza, Johannes Adamcyk, Stefan Beisl, Christoph Kornpointner, Heidi Halbwirth, Anton Friedl
May 4, 2021
Cannabinoids have gained significant interest as they may have pharmaceutical and nutritional applications to treat various diseases (sclerosis, glaucoma, and epilepsy, among others). Hemp (Cannabis sativa L.) has been studied recently as a source of cannabinoids, given the low concentration of tetrahydrocannabinol and comparatively high concentration of cannabidiol. Most of the plant’s fractions are used (blossoms, stem, and seeds), but the processing of the blossom leaves a residue, threshing residues, which could still be used to extract cannabinoids, aiming for an integral usage of the plant. Different technologies have been applied for cannabinoid extraction. Among these, pressurized liquid extraction (PLE) stands out due to the ease of application and efficiency. This work evaluates the influence of temperature, pressure, extraction time, and the number of cycles for the PLE of cannabinoids from hemp threshing residues using ethanol. Results show that low pressures, 100 °C, and 60 min are sufficient to achieve extraction yields of 19.8 mg of cannabidiol per g of dry hemp, which corresponds to an extraction efficiency of 99.3%. These results show this technology’s potential for cannabinoid extraction (mainly cannabidiol) and further open the perspective to valorize the residues and other parts of hemp plants.
Keywords
biorefineries, cannabidiol, cannabinoids, hemp residues, Renewable and Sustainable Energy
Suggested Citation
Serna-Loaiza S, Adamcyk J, Beisl S, Kornpointner C, Halbwirth H, Friedl A. Pressurized Liquid Extraction of Cannabinoids from Hemp Processing Residues: Evaluation of the Influencing Variables. (2021). LAPSE:2021.0334v1
Author Affiliations
Serna-Loaiza S: Institute of Chemical, Environmental and Bioscience Engineering, Technische Universität Wien, Vienna 1060, Austria [ORCID]
Adamcyk J: Institute of Chemical, Environmental and Bioscience Engineering, Technische Universität Wien, Vienna 1060, Austria
Beisl S: Institute of Chemical, Environmental and Bioscience Engineering, Technische Universität Wien, Vienna 1060, Austria [ORCID]
Kornpointner C: Institute of Chemical, Environmental and Bioscience Engineering, Technische Universität Wien, Vienna 1060, Austria
Halbwirth H: Institute of Chemical, Environmental and Bioscience Engineering, Technische Universität Wien, Vienna 1060, Austria
Friedl A: Institute of Chemical, Environmental and Bioscience Engineering, Technische Universität Wien, Vienna 1060, Austria [ORCID]
Journal Name
Processes
Volume
8
Issue
11
Article Number
E1334
Year
2020
Publication Date
2020-10-22
ISSN
2227-9717
Version Comments
Original Submission
Other Meta
PII: pr8111334, Publication Type: Journal Article
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LAPSE:2021.0334v1
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https://doi.org/10.3390/pr8111334
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May 4, 2021
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CC BY 4.0
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May 4, 2021
 
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Calvin Tsay
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