LAPSE:2019.1185
Published Article

LAPSE:2019.1185
Show Me the Money! Process Modeling in Pharma from the Investor’s Point of View
November 24, 2019
Abstract
Process modeling in pharma is gradually gaining momentum in process development but budget restrictions are growing. We first examine whether and how current practices rationalize within a decision process framework with a fictitious investor facing a decision problem subject to incomplete information. We then develop an algorithmic procedure for investment evaluation on both monetary and diffusion-of-innovation fronts. Our methodology builds upon discounted cash flow analysis and Bayesian inference and utilizes the Rogers diffusion of innovation paradigm for computing lower expected returns. We also introduce a set of intangible metrics for quantifying the level of diffusion of process modeling within an organization.
Process modeling in pharma is gradually gaining momentum in process development but budget restrictions are growing. We first examine whether and how current practices rationalize within a decision process framework with a fictitious investor facing a decision problem subject to incomplete information. We then develop an algorithmic procedure for investment evaluation on both monetary and diffusion-of-innovation fronts. Our methodology builds upon discounted cash flow analysis and Bayesian inference and utilizes the Rogers diffusion of innovation paradigm for computing lower expected returns. We also introduce a set of intangible metrics for quantifying the level of diffusion of process modeling within an organization.
Record ID
Keywords
diffusion of innovation, process modeling, return on investment
Subject
Suggested Citation
Varsakelis C, Dessoy S, von Stosch M, Pysik A. Show Me the Money! Process Modeling in Pharma from the Investor’s Point of View. (2019). LAPSE:2019.1185
Author Affiliations
Varsakelis C: Technical Research & Development, GSK Biologicals, 1330 Rixensart, Belgium [ORCID]
Dessoy S: Technical Research & Development, GSK Biologicals, 1330 Rixensart, Belgium
von Stosch M: Technical Research & Development, GSK Biologicals, 1330 Rixensart, Belgium
Pysik A: Technical Research & Development, GSK Biologicals, 1330 Rixensart, Belgium
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Dessoy S: Technical Research & Development, GSK Biologicals, 1330 Rixensart, Belgium
von Stosch M: Technical Research & Development, GSK Biologicals, 1330 Rixensart, Belgium
Pysik A: Technical Research & Development, GSK Biologicals, 1330 Rixensart, Belgium
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Journal Name
Processes
Volume
7
Issue
9
Article Number
E596
Year
2019
Publication Date
2019-09-04
ISSN
2227-9717
Version Comments
Original Submission
Other Meta
PII: pr7090596, Publication Type: Journal Article
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Published Article

LAPSE:2019.1185
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https://doi.org/10.3390/pr7090596
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[v1] (Original Submission)
Nov 24, 2019
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Nov 24, 2019
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https://psecommunity.org/LAPSE:2019.1185
Record Owner
Calvin Tsay
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