Abstract
Chemical process control relies on a tightly controlled, narrow range of margins for critical variables, ensuring process stability and safeguarding equipment from potential accidents. The availability of historical process data is limited to a specific setpoint of operation. This challenge raises issues for process monitoring in predicting and adjusting to deviations outside of the range of operational parameters. Therefore, this paper proposes simulation-assisted deep transfer learning for predicting and optimizing the final purity and production capacity of the glycerin purification process. The proposed network is trained by the simulation domain to generate a base feature extractor, which is then fine-tuned using few-shot learning techniques on the target learner to extend the working domain of the model beyond historical practice. The result shows that the proposed model improved prediction performance by 24.22% in predicting water content and 79.72% in glycerin prediction over the conventional deep learning model. Additionally, the implementation of the proposed model identified production and product quality improvements for enhancing the glycerin purification process.