The present work is a numerical analysis of electro-thermo convection, occurring in a square differentially heated cavity filled with a dielectric fluid. The cavity experiences the combined effects of viscous, electrical, and thermal forces. The equations modelling the physical problem are solved via the finite volume approach. The study focuses on the effect of cavity tilt on the fluid flow structure and thermal performance inside the enclosure under the action of an electric field. A parametric study was performed, where the tilt angle is getting varied between 0° and 90°, as well as the Rayleigh number (5000 ≤ Ra ≤ 250,000) and the electric field (0 ≤ T ≤ 800). Furthermore, the electric charge injection level C, the mobility M and the Prandtl Pr numbers were all adjusted to a value of 10. The obtained results demonstrate that the hydrodynamic and thermal fields are significantly impacted by the cavity inclination. In addition, regardless of the thermal Rayleigh’s number, high electric field values could govern fluid movement through electric forces. Electro-convection typically demonstrates an oscillating flow due to the tilting of the cavity which gives rise to a bicellular regime occupying the entire cavity. A correlation has been established to estimate heat transfer by considering various system parameters such as cavity inclination, electrical Rayleigh number, and thermal Rayleigh number.