LAPSE:2023.6055
Published Article

LAPSE:2023.6055
Development and Commissioning of a Small-Scale, Modular and Integrated Plant for the Quasi-Continuous Production of Crystalline Particles
February 23, 2023
Abstract
Increasing global competition, volatile markets and the demand for individual products challenge companies in almost all business sectors and require innovative solutions. In the chemical and pharmaceutical industries, these include modular design, the integration of several unit operations in one apparatus and the development of small-scale, versatile multipurpose plants. An example for such a modular, integrated and small-scale system is the belt crystallizer. This device combines the process steps cooling crystallization, solid-liquid separation and contact drying in a single plant. The basis of the apparatus is a belt filter in which the vacuum trays below the filter medium are replaced by temperature control and filtration units. Due to identical dimensions, it is possible to arrange the individual functional units in any order, which in turn allows a high degree of flexibility and rapid adaptation to customer requirements. Within the scope of the publication, the commissioning of the belt crystallizer takes place. First of all, the general functionality of the plant concept is demonstrated using sucrose as model system. Further experiments show that the particle size and the distribution width of the manufactured crystals can be specifically influenced by the selected process parameters, e.g., temperature profile during cooling and residence time.
Increasing global competition, volatile markets and the demand for individual products challenge companies in almost all business sectors and require innovative solutions. In the chemical and pharmaceutical industries, these include modular design, the integration of several unit operations in one apparatus and the development of small-scale, versatile multipurpose plants. An example for such a modular, integrated and small-scale system is the belt crystallizer. This device combines the process steps cooling crystallization, solid-liquid separation and contact drying in a single plant. The basis of the apparatus is a belt filter in which the vacuum trays below the filter medium are replaced by temperature control and filtration units. Due to identical dimensions, it is possible to arrange the individual functional units in any order, which in turn allows a high degree of flexibility and rapid adaptation to customer requirements. Within the scope of the publication, the commissioning of the belt crystallizer takes place. First of all, the general functionality of the plant concept is demonstrated using sucrose as model system. Further experiments show that the particle size and the distribution width of the manufactured crystals can be specifically influenced by the selected process parameters, e.g., temperature profile during cooling and residence time.
Record ID
Keywords
crystallization, integrated process design, modularization, plant engineering, solid-liquid separation
Subject
Suggested Citation
Dobler T, Buchheiser S, Gleiß M, Nirschl H. Development and Commissioning of a Small-Scale, Modular and Integrated Plant for the Quasi-Continuous Production of Crystalline Particles. (2023). LAPSE:2023.6055
Author Affiliations
Dobler T: Karlsruhe Institute of Technology (KIT), Institute of Mechanical Process Engineering and Mechanics, Strasse am Forum 8, 76131 Karlsruhe, Germany
Buchheiser S: Karlsruhe Institute of Technology (KIT), Institute of Mechanical Process Engineering and Mechanics, Strasse am Forum 8, 76131 Karlsruhe, Germany
Gleiß M: Karlsruhe Institute of Technology (KIT), Institute of Mechanical Process Engineering and Mechanics, Strasse am Forum 8, 76131 Karlsruhe, Germany
Nirschl H: Karlsruhe Institute of Technology (KIT), Institute of Mechanical Process Engineering and Mechanics, Strasse am Forum 8, 76131 Karlsruhe, Germany
Buchheiser S: Karlsruhe Institute of Technology (KIT), Institute of Mechanical Process Engineering and Mechanics, Strasse am Forum 8, 76131 Karlsruhe, Germany
Gleiß M: Karlsruhe Institute of Technology (KIT), Institute of Mechanical Process Engineering and Mechanics, Strasse am Forum 8, 76131 Karlsruhe, Germany
Nirschl H: Karlsruhe Institute of Technology (KIT), Institute of Mechanical Process Engineering and Mechanics, Strasse am Forum 8, 76131 Karlsruhe, Germany
Journal Name
Processes
Volume
9
Issue
4
First Page
663
Year
2021
Publication Date
2021-04-09
ISSN
2227-9717
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Original Submission
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PII: pr9040663, Publication Type: Journal Article
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LAPSE:2023.6055
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https://doi.org/10.3390/pr9040663
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Feb 23, 2023
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