Advance in renewable penetration has promoted the interaction between the AC and DC power system and multi-energy sources. However, the disparate nature of different energy utilization technologies presents strong challenges for the economic dispatch of such a complex system. This paper proposes a comprehensive characterization of the AC/DC power system considering multi-energy and renewable integration. Detailed models are elaborated for the AC/DC power grid, the district heating system (DHS), coupling units, and renewables to describe their inner interactions accurately. On this basis, an economic dispatch method is developed to minimize the operation cost and renewable’s abandonment. Simulations indicate that the interaction between the AC/DC power systems and multi-energy sources can enhance voltage levels and improve operational economy.