This article studies the calculation method for the tooth root bending stress of a high-tooth gear pair with a high contact ratio. The boundary point of the double-tooth meshing zone of the high-tooth gear pair is used as the loading point for the load, and the calculation formula for the bending stress at the dangerous section of the tooth root is obtained. By using ANSYS finite element simulation, the effect of the addendum coefficient, pressure angle, and other gear parameters on the bending stress of the tooth root is studied. The analysis shows that increasing the pressure angle will reduce the bending strength of the tooth root. Increasing the coefficient of a tooth’s top height will lead to an increase in the bending strength of the tooth root. Comparing the finite element analysis (FEA) results with the theoretical calculation results, the analysis shows that under low loads, the maximum error of the theoretical calculation values of the driving toothed gear and driven gear shall not exceed 13.53% and 15.42%, respectively. Under high loads, the maximum theoretical errors of the driving toothed gear and driven gear shall not exceed 8.78% and 10.91%, respectively. This verifies the correctness of the calculation method, which is of great significance for improving the load-bearing capacity of high-tooth gears and for guiding tooth shape design.