With the increase in the voltage level and number of transmission lines, the probability of lightning strikes on transmission lines is significantly increased, while lightning breakage accidents occur frequently. Therefore, an explosion airflow arc-quenching gap for 110 kV transmission lines was developed based on the idea of rapid extinction. A mathematical model of the detonation wave based on the CJ (Chapman−Jouget) detonation wave theory was developed to calculate the detonation air pressure and analyze its influencing factors. ANSYS software and the magnetohydrodynamic (MHD) model were used to simulate the process of detonation airflow coupled with an arc, and the simulation results indicated that the power frequency arc was evidently suppressed with the influence of airflow, which can effectively prevent arcing. A combined impulse and power frequency test and arc-quenching tests were performed to verify the effectiveness of the arc-quenching gap. The results of the combined test indicated that the arc burn time was 0.1 ms and that no power frequency continuous current was displayed. The results ensured the accuracy of the simulation model. The results of the arc-quenching tests proved that the explosion airflow can extinguish a power frequency arc with an amplitude of 40 kA in half of a power frequency arc cycle.