In order to reach the ambitious decarbonizing goals set by the European Union for 2030, deep renovation of the existing European building stock is a key issue. Within this context, the recently funded H2020 project “e-SAFE” is investigating market-ready wooden envelope renovation solutions for non-historic buildings, which encompass both energy and seismic improvement. The research carried out in the project aims at developing, testing and demonstrating these solutions on a real pilot. More specifically, this paper presents preliminary analyses to verify that the solutions satisfy the requisites set by the national regulations in force in most European countries, in terms of hygrothermal and acoustic performance. The analysis, carried out following relevant technical European Standards and based on calculations, considers different climate conditions and existing wall structures, selected amongst those most commonly adopted in Europe. The results show that the addition of a Cross Laminated Timber (CLT) layer with some wooden-based insulation on the outer side allows reaching very good thermal and acoustic performance. However, interstitial condensation may occur in cold climates under high indoor humidity values. This aspect deserves further investigation accounting for the transient behavior of the walls and all vapor transport mechanisms.