LAPSE:2023.1485
Published Article
LAPSE:2023.1485
Comparative Insights into the Antimicrobial, Antioxidant, and Nutritional Potential of the Solanum nigrum Complex
February 21, 2023
Abstract
is a traditional medicinal plant renowned as a cure for many diseases due to the presence of bioactive compounds. The Solanum nigrum complex refers to a group of more than 30 closely related but morphologically distinct taxa. Five indigenous taxa of this complex were investigated for their medicinal potential by using methanolic extracts. The efficacy of each plant was different for each of the seven bacteria studied. On comparing the MIC values, S. americanum was found to be most potent against Bacillus licheniformis (34 µg/mL), S. chenopodioides against Escherichia coli (78 µg/mL), S. nigrum against Bacillus licheniformis (49 µg/mL) and Escherichia coli (49 µg/mL), S. retroflexum against Escherichia coli (30 µg/mL), and S. villosum against Proteus mirabilis (45 µg/mL). The extracts were also subjected to six antioxidant assays. Moderate scavenging activity was observed by all plants in the DPPH free radical assay, but S. chenopodioides was the most effective. The total phenolic contents of the five plants were comparable, but the gallic acid equivalents of S. americanum and S. nigrum were the highest (26.58 mg/100 g GAE). The highest Trolox equivalent antioxidant capacity was observed for S. retroflexum, with the ABTS assay giving a TEAC value of 33.88 mM/100 g of dry weight. Metal-chelating activity against Fe2+ was observed to be highest for S. chenopodioides (70.37%). The FRAP value of S. nigrum was the highest (8.5 mM FeSO4·7H2O) among all taxa. The lipid peroxidation trend was very similar for all five samples. The results suggest the specified medicinal use of different members of the Solanum nigrum complex, which will also have significant nutritional value.
is a traditional medicinal plant renowned as a cure for many diseases due to the presence of bioactive compounds. The Solanum nigrum complex refers to a group of more than 30 closely related but morphologically distinct taxa. Five indigenous taxa of this complex were investigated for their medicinal potential by using methanolic extracts. The efficacy of each plant was different for each of the seven bacteria studied. On comparing the MIC values, S. americanum was found to be most potent against Bacillus licheniformis (34 µg/mL), S. chenopodioides against Escherichia coli (78 µg/mL), S. nigrum against Bacillus licheniformis (49 µg/mL) and Escherichia coli (49 µg/mL), S. retroflexum against Escherichia coli (30 µg/mL), and S. villosum against Proteus mirabilis (45 µg/mL). The extracts were also subjected to six antioxidant assays. Moderate scavenging activity was observed by all plants in the DPPH free radical assay, but S. chenopodioides was the most effective. The total phenolic contents of the five plants were comparable, but the gallic acid equivalents of S. americanum and S. nigrum were the highest (26.58 mg/100 g GAE). The highest Trolox equivalent antioxidant capacity was observed for S. retroflexum, with the ABTS assay giving a TEAC value of 33.88 mM/100 g of dry weight. Metal-chelating activity against Fe2+ was observed to be highest for S. chenopodioides (70.37%). The FRAP value of S. nigrum was the highest (8.5 mM FeSO4·7H2O) among all taxa. The lipid peroxidation trend was very similar for all five samples. The results suggest the specified medicinal use of different members of the Solanum nigrum complex, which will also have significant nutritional value.
Record ID
Keywords
antibacterial potential, antioxidant potential, herbal medicine, methanol extract, nutritional value, Solanum nigrum complex
Subject
Suggested Citation
Mohyuddin A, Kurniawan TA, Khan ZUD, Nadeem S, Javed M, Dera AA, Iqbal S, Awwad NS, Ibrahium HA, Abourehab MAS, Rabea S, Elkaeed EB, Asghar MN, Saeed S. Comparative Insights into the Antimicrobial, Antioxidant, and Nutritional Potential of the Solanum nigrum Complex. (2023). LAPSE:2023.1485
Author Affiliations
Mohyuddin A: Department of Chemistry, School of Science, University of Management and Technology, Lahore 54770, Pakistan [ORCID]
Kurniawan TA: Key Laboratory of the Coastal and Wetland Ecosystems, Ministry of Education, College of Ecology and Environment, Xiamen University, Xiamen 361102, China [ORCID]
Khan ZUD: Department of Botany, Government College University, Lahore 54000, Pakistan
Nadeem S: Department of Chemistry, School of Science, University of Management and Technology, Lahore 54770, Pakistan
Javed M: Department of Chemistry, School of Science, University of Management and Technology, Lahore 54770, Pakistan
Dera AA: Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Khalid University, Abha 61421, Saudi Arabia
Iqbal S: Department of Chemistry, School of Natural Sciences (SNS), National University of Science and Technology (NUST), H-12, Islamabad 46000, Pakistan [ORCID]
Awwad NS: Chemistry Department, Faculty of Science, King Khalid University, Abha 61413, Saudi Arabia [ORCID]
Ibrahium HA: Biology Department, Faculty of Science, King Khalid University, Abha 61413, Saudi Arabia; Department of Semi Pilot Plant, Nuclear Materials Authority, El Maadi 4710030, Egypt
Abourehab MAS: Department of Pharmaceutics College of Pharmacy Umm Al-Qura University, Makkah 21955, Saudi Arabia; Department of pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy Minia University, Minia 61519, Egypt [ORCID]
Rabea S: Department of Pharmaceutical Sciences, College of Pharmacy, AlMaarefa University, Riyadh 13713, Saudi Arabia [ORCID]
Elkaeed EB: Department of Pharmaceutical Sciences, College of Pharmacy, AlMaarefa University, Riyadh 13713, Saudi Arabia [ORCID]
Asghar MN: Department of Chemistry, Forman Christian College (A Chartered University), Lahore 54600, Pakistan
Saeed S: Institute of Biochemistry and Biotechnology, University of Veterinary and Animal Science, Lahore 54000, Pakistan
Kurniawan TA: Key Laboratory of the Coastal and Wetland Ecosystems, Ministry of Education, College of Ecology and Environment, Xiamen University, Xiamen 361102, China [ORCID]
Khan ZUD: Department of Botany, Government College University, Lahore 54000, Pakistan
Nadeem S: Department of Chemistry, School of Science, University of Management and Technology, Lahore 54770, Pakistan
Javed M: Department of Chemistry, School of Science, University of Management and Technology, Lahore 54770, Pakistan
Dera AA: Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Khalid University, Abha 61421, Saudi Arabia
Iqbal S: Department of Chemistry, School of Natural Sciences (SNS), National University of Science and Technology (NUST), H-12, Islamabad 46000, Pakistan [ORCID]
Awwad NS: Chemistry Department, Faculty of Science, King Khalid University, Abha 61413, Saudi Arabia [ORCID]
Ibrahium HA: Biology Department, Faculty of Science, King Khalid University, Abha 61413, Saudi Arabia; Department of Semi Pilot Plant, Nuclear Materials Authority, El Maadi 4710030, Egypt
Abourehab MAS: Department of Pharmaceutics College of Pharmacy Umm Al-Qura University, Makkah 21955, Saudi Arabia; Department of pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy Minia University, Minia 61519, Egypt [ORCID]
Rabea S: Department of Pharmaceutical Sciences, College of Pharmacy, AlMaarefa University, Riyadh 13713, Saudi Arabia [ORCID]
Elkaeed EB: Department of Pharmaceutical Sciences, College of Pharmacy, AlMaarefa University, Riyadh 13713, Saudi Arabia [ORCID]
Asghar MN: Department of Chemistry, Forman Christian College (A Chartered University), Lahore 54600, Pakistan
Saeed S: Institute of Biochemistry and Biotechnology, University of Veterinary and Animal Science, Lahore 54000, Pakistan
Journal Name
Processes
Volume
10
Issue
8
First Page
1455
Year
2022
Publication Date
2022-07-25
ISSN
2227-9717
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Original Submission
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PII: pr10081455, Publication Type: Journal Article
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LAPSE:2023.1485
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https://doi.org/10.3390/pr10081455
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