For the purpose of clarifying the seismic response characteristics of fractured-cavity reservoirs of Dengying Formation in the central Sichuan Basin, the paper first intends to establish three geological models of fracture cave reservoirs based on drilling, logging, and core data of the Dengying Formation in the central Sichuan Basin. Then, the formation reflection is calculated with reference to anisotropic Horizontal Transverse Isotropy (HTI) medium. Finally, further research on Amplitude Variation with Azimuth (AVAZ) seismic forward modeling has been conducted to clarify the seismic response characteristics of different reservoir types in the study area. The results suggest that: Seismic response characteristics of fractured-cavity reservoirs are controlled by incident angle and azimuth angle of seismic waves in different types of reservoirs. The incident angle of the seismic wave controls the difference in amplitude caused by different micro-fracture densities, and the azimuth angle controls the identification ability of the micro-fracture direction. The increase in incident angle brings about a gradual decline in amplitude. The magnitude reaches the highest when the azimuth is parallel to the normal direction of the fracture surface; however, it’ll come down to the lowest as the azimuth is perpendicular to the normal direction of the fracture surface. The fracture density fails to affect the amplitude as long as the azimuth angle is parallel to the direction of the fracture. However, the decreased amplitude reflects the increasing fracture density as the azimuth angle is identical to the normal direction of the fracture surface. The comparison between the theoretical model of three different types of fractured-cavity reservoirs and the actual uphole trace shows that the model has high accuracy. The prospect of seismic identification of fractured-cavern reservoirs, based on the results, can provide us with feasible and applicable evidence for future research on seismic identification of reservoirs and prediction of fracture distribution in the Dengying Formation of central Sichuan.