Advice and best practices for teaching conceptual process flowsheeting, simulation, and design at the third year undergraduate level. Discusses setting course goals, integration with the rest of the curriculum, and delivery techniques. Practical strategies for tutorials, exams, lectures, and projects. Training TAs for experiential learning workshops. Best practices in teaching distillation design. This is the Award Lecture for AIChE's David Himmelblau Award for Innovations in Computer-Based Chemical Engineering Education. Live lecture given via APMonitor.com as a part of the AIChE's Computing and Systems Technology division webinar series.