LAPSE:2020.0809
Published Article
LAPSE:2020.0809
Controlled Drug Delivery Vehicles in Veterinary Oncology: State-of-the-Art and Future Directions
July 7, 2020
Controlled drug delivery systems can be used to carry several anticancer agents, including classical chemotherapeutic agents such as doxorubicin, paclitaxel or cisplatin, and are also used for the encapsulation of tyrosine kinase inhibitors and monoclonal antibodies. Usually, the controlled systems are used to decrease drug toxicity, increase local drug concentration or target specific organs or systems. In dogs, liposomal doxorubicin is the most known controlled drug delivery vehicle in veterinary medicine. However, several antitumor drugs can be encapsulated within these systems. Since the delivery vehicles are a relatively new topic in veterinary oncology, this review aims to discuss the current knowledge regarding the controlled drug delivery vehicles and discuss the current challenges and future direction of its use in veterinary oncology.
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Keywords
dogs, doxorubicin, nanoparticles, nanotechnology
Subject
Suggested Citation
Lainetti PDF, Zuliani F, Leis-Filho AF, Fonseca Alves RH, Fonseca-Alves CE. Controlled Drug Delivery Vehicles in Veterinary Oncology: State-of-the-Art and Future Directions. (2020). LAPSE:2020.0809
Author Affiliations
Lainetti PDF: Department of Veterinary Surgery and Animal Reproduction, School of Veterinary Medicine and Animal Science, São Paulo State University—UNESP, Botucatu 18618-681, Brazil [ORCID]
Zuliani F: Department of Veterinary Surgery and Animal Reproduction, School of Veterinary Medicine and Animal Science, São Paulo State University—UNESP, Botucatu 18618-681, Brazil
Leis-Filho AF: Department of Veterinary Surgery and Animal Reproduction, School of Veterinary Medicine and Animal Science, São Paulo State University—UNESP, Botucatu 18618-681, Brazil
Fonseca Alves RH: John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA 02138, USA [ORCID]
Fonseca-Alves CE: Department of Veterinary Surgery and Animal Reproduction, School of Veterinary Medicine and Animal Science, São Paulo State University—UNESP, Botucatu 18618-681, Brazil; Institute of Health Sciences, Universidade Paulista—UNIP, Bauru 17048-290, Brazi [ORCID]
Zuliani F: Department of Veterinary Surgery and Animal Reproduction, School of Veterinary Medicine and Animal Science, São Paulo State University—UNESP, Botucatu 18618-681, Brazil
Leis-Filho AF: Department of Veterinary Surgery and Animal Reproduction, School of Veterinary Medicine and Animal Science, São Paulo State University—UNESP, Botucatu 18618-681, Brazil
Fonseca Alves RH: John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA 02138, USA [ORCID]
Fonseca-Alves CE: Department of Veterinary Surgery and Animal Reproduction, School of Veterinary Medicine and Animal Science, São Paulo State University—UNESP, Botucatu 18618-681, Brazil; Institute of Health Sciences, Universidade Paulista—UNIP, Bauru 17048-290, Brazi [ORCID]
Journal Name
Processes
Volume
8
Issue
5
Article Number
E541
Year
2020
Publication Date
2020-05-05
Published Version
ISSN
2227-9717
Version Comments
Original Submission
Other Meta
PII: pr8050541, Publication Type: Review
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Published Article
LAPSE:2020.0809
This Record
External Link
doi:10.3390/pr8050541
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433
Version History
[v1] (Original Submission)
Jul 7, 2020
Verified by curator on
Jul 7, 2020
This Version Number
v1
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URL Here
https://psecommunity.org/LAPSE:2020.0809
Original Submitter
Calvin Tsay
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