LAPSE:2023.5619v1
Published Article

LAPSE:2023.5619v1
Bayesian Analysis for Cardiovascular Risk Factors in Ischemic Heart Disease
February 23, 2023
Abstract
Ischemic heart disease (or Coronary Artery Disease) is the most common cause of death in various countries, characterized by reduced blood supply to the heart. Statistical models make an impact in evaluating the risk factors that are responsible for mortality and morbidity during IHD (Ischemic heart disease). In general, geometric or Poisson distributions can underestimate the zero-count probability and hence make it difficult to identify significant effects of covariates for improving conditions of heart disease due to regional wall motion abnormalities. In this work, a flexible class of zero inflated models is introduced. A Bayesian estimation method is developed as an alternative to traditionally used maximum likelihood-based methods to analyze such data. Simulation studies show that the proposed method has a better small sample performance than the classical method, with tighter interval estimates and better coverage probabilities. Although the prevention of CAD has long been a focus of public health policy, clinical medicine, and biomedical scientific investigation, the prevalence of CAD remains high despite current strategies for prevention and treatment. Various comprehensive searches have been performed in the MEDLINE, HealthSTAR, and Global Health databases for providing insights into the effects of traditional and emerging risk factors of CAD. A real-life data set is illustrated for the proposed method using WinBUGS.
Ischemic heart disease (or Coronary Artery Disease) is the most common cause of death in various countries, characterized by reduced blood supply to the heart. Statistical models make an impact in evaluating the risk factors that are responsible for mortality and morbidity during IHD (Ischemic heart disease). In general, geometric or Poisson distributions can underestimate the zero-count probability and hence make it difficult to identify significant effects of covariates for improving conditions of heart disease due to regional wall motion abnormalities. In this work, a flexible class of zero inflated models is introduced. A Bayesian estimation method is developed as an alternative to traditionally used maximum likelihood-based methods to analyze such data. Simulation studies show that the proposed method has a better small sample performance than the classical method, with tighter interval estimates and better coverage probabilities. Although the prevention of CAD has long been a focus of public health policy, clinical medicine, and biomedical scientific investigation, the prevalence of CAD remains high despite current strategies for prevention and treatment. Various comprehensive searches have been performed in the MEDLINE, HealthSTAR, and Global Health databases for providing insights into the effects of traditional and emerging risk factors of CAD. A real-life data set is illustrated for the proposed method using WinBUGS.
Record ID
Keywords
Bayesian inference, Gibbs sampling, log-likelihood, Markov Chain Monte Carlo, zero inflated model
Suggested Citation
Ghosh S, Samanta G, De la Sen M. Bayesian Analysis for Cardiovascular Risk Factors in Ischemic Heart Disease. (2023). LAPSE:2023.5619v1
Author Affiliations
Ghosh S: Department of Mathematics, Indian Institute of Engineering Science and Technology, Shibpur, Howrah 711103, India
Samanta G: Department of Mathematics, Indian Institute of Engineering Science and Technology, Shibpur, Howrah 711103, India [ORCID]
De la Sen M: Institute of Research and Development of Processes, University of the Basque Country, 48940 Leioa, Spain [ORCID]
Samanta G: Department of Mathematics, Indian Institute of Engineering Science and Technology, Shibpur, Howrah 711103, India [ORCID]
De la Sen M: Institute of Research and Development of Processes, University of the Basque Country, 48940 Leioa, Spain [ORCID]
Journal Name
Processes
Volume
9
Issue
7
First Page
1242
Year
2021
Publication Date
2021-07-19
ISSN
2227-9717
Version Comments
Original Submission
Other Meta
PII: pr9071242, Publication Type: Journal Article
Record Map
Published Article

LAPSE:2023.5619v1
This Record
External Link

https://doi.org/10.3390/pr9071242
Publisher Version
Download
Meta
Record Statistics
Record Views
220
Version History
[v1] (Original Submission)
Feb 23, 2023
Verified by curator on
Feb 23, 2023
This Version Number
v1
Citations
Most Recent
This Version
URL Here
https://psecommunity.org/LAPSE:2023.5619v1
Record Owner
Auto Uploader for LAPSE
Links to Related Works
