The problem of casing deformation caused by large-scale hydraulic fracturing in shale oil wells severely restricts the efficient development of Gulong shale oil. In order to clarify the mechanism of casing deformation in shale oil wells, comprehensive analysis was conducted on engineering factors, multi-arm caliper logging, seismic attributes, and the distribution characteristics of casing deformations. This study shows that casing strength, cementing quality, and wellbore curvature are not the main controlling factors for casing deformation. Casing deformation is caused by the communication between hydraulic fractures and natural fractures during the fracturing process, which increases the fluid pressure in the natural fracture and induces shear slip, resulting in casing deformation due to shear stress. Based on the understanding of the mechanism of casing deformation in shale oil wells, two targeted casing deformation prevention and control methods are proposed. First, temporary plugging was implemented during the hydraulic fracturing process when the fluid volume reached 1000 m3, and the pumping rate was reduced to below 16 m3/min to reduce the internal fluid pressure of the fractures and control fracture slip, thereby minimizing the risk of casing deformation. Second, hollow particles were added to the cement to enhance the consolidation effect of the cement sheath and mitigate casing deformation caused by fracture slip. Research indicates that a hollow particle content of 15% can meet the requirements for casing deformation control in Gulong shale oil. These research results can provide important references for the prediction and prevention of casing deformation risks in shale oil and similar unconventional reservoirs during hydraulic fracturing.