The development of compression ignition engines depends mainly on using alternative fuels, such as alcohols. The paper presents the results of tests of a stationary compression ignition engine fueled with mixtures of diesel oil and n-butanol with an energy share from 0 to 60%. The combustion and emission results of a dual-fuel engine were compared to a conventional diesel-only engine. As part of the work, the combustion process, including changes in pressure and heat release rate, as well as exhaust emissions from the test engine, were investigated. The main operational parameters of the engine were determined, including mean indicated pressure, thermal efficiency and specific energy consumption. Moreover, the stability of the engine operation was analyzed. The research shows that the 60% addition of n-butanol to diesel fuel increases the ignition delay (by 39%) and shortens the combustion duration (by 57%). In addition, up to 40%, it results in increased pmax, HRRmax and PPRmax. The engine was characterized by the highest efficiency, equal to 41.35% when operating on DB40. In the whole range of alcohol content, the dual-fuel engine was stable. With the increase of n-butanol content to 40%, the emission of NOx increased. The lowest concentration of CO was obtained during the combustion of DB50. After the initial increase (for DB20), the THC emission was reduced to the lowest value for DB40. Increasing the energy share of alcohol to 60% resulted in a significant, more than 43 times, reduction in soot emissions.