LAPSE:2023.3092
Published Article
LAPSE:2023.3092
Novel Green Approaches for the Preparation of Gold Nanoparticles and Their Promising Potential in Oncology
February 21, 2023
Abstract
The difficulty of achieving targeted drug delivery following administration of currently marketed anticancer therapeutics is a still a concern. Metallic nanoparticles (NPs) developed through nanotechnology breakthroughs appear to be promising in this regard. Research studies pertaining to gold NPs have indicated their promising applicability in cancer diagnosis, drug delivery and therapy. These NPs have also recently paved the path for precise drug delivery and site-specific targeting. Our review paper thus highlights the scope and impact of biogenetically generated gold nanoparticles (NPs) in cancer therapy. In a critical, constructive, and methodical manner, we compare the advantages offered by gold NPs over other metal NPs. Moreover, we also focus on novel ‘greener’ strategies that have been recently explored for the preparation of gold NPs and shed light on the disadvantages of conventional NP synthesis routes. Future prospects pertaining to the use of gold NPs in oncotherapy and domains that require further investigation are also addressed.
The difficulty of achieving targeted drug delivery following administration of currently marketed anticancer therapeutics is a still a concern. Metallic nanoparticles (NPs) developed through nanotechnology breakthroughs appear to be promising in this regard. Research studies pertaining to gold NPs have indicated their promising applicability in cancer diagnosis, drug delivery and therapy. These NPs have also recently paved the path for precise drug delivery and site-specific targeting. Our review paper thus highlights the scope and impact of biogenetically generated gold nanoparticles (NPs) in cancer therapy. In a critical, constructive, and methodical manner, we compare the advantages offered by gold NPs over other metal NPs. Moreover, we also focus on novel ‘greener’ strategies that have been recently explored for the preparation of gold NPs and shed light on the disadvantages of conventional NP synthesis routes. Future prospects pertaining to the use of gold NPs in oncotherapy and domains that require further investigation are also addressed.
Record ID
Keywords
biogenetic, cancer treatment, gold nanoparticles, nanomedicines, pathway
Subject
Suggested Citation
Bhattacharya T, Das D, Borges e Soares GA, Chakrabarti P, Ai Z, Chopra H, Hasan MA, Cavalu S. Novel Green Approaches for the Preparation of Gold Nanoparticles and Their Promising Potential in Oncology. (2023). LAPSE:2023.3092
Author Affiliations
Bhattacharya T: Hubei Collaborative Innovation Centre for Advanced Organic Chemical Materials, Hubei University, Wuhan 430062, China; Innovation, Incubation & Industry (I-Cube) Laboratory, Techno India NJR Institute of Technology, Udaipur 313003, Rajasthan, India [ORCID]
Das D: School Of Community Science & Technology IIEST Shibpur, Howrah 711103, West Bengal, India; PRCS Technologies 94, Phears Lane, Kolkata 700012, West Bengal, India
Borges e Soares GA: Department of Medicinal and Biological Chemistry, University of Toledo, 3000 Arlington Ave., Toledo, OH 43614, USA [ORCID]
Chakrabarti P: Innovation, Incubation & Industry (I-Cube) Laboratory, Techno India NJR Institute of Technology, Udaipur 313003, Rajasthan, India
Ai Z: Hubei Collaborative Innovation Centre for Advanced Organic Chemical Materials, Hubei University, Wuhan 430062, China
Chopra H: Chitkara College of Pharmacy, Chitkara University, Rajpura 140401, Punjab, India [ORCID]
Hasan MA: Faculty of Medicine and Pharmacy, University of Oradea, P-ta 1 Decembrie 10, 410087 Oradea, Romania
Cavalu S: Faculty of Medicine and Pharmacy, University of Oradea, P-ta 1 Decembrie 10, 410087 Oradea, Romania [ORCID]
Das D: School Of Community Science & Technology IIEST Shibpur, Howrah 711103, West Bengal, India; PRCS Technologies 94, Phears Lane, Kolkata 700012, West Bengal, India
Borges e Soares GA: Department of Medicinal and Biological Chemistry, University of Toledo, 3000 Arlington Ave., Toledo, OH 43614, USA [ORCID]
Chakrabarti P: Innovation, Incubation & Industry (I-Cube) Laboratory, Techno India NJR Institute of Technology, Udaipur 313003, Rajasthan, India
Ai Z: Hubei Collaborative Innovation Centre for Advanced Organic Chemical Materials, Hubei University, Wuhan 430062, China
Chopra H: Chitkara College of Pharmacy, Chitkara University, Rajpura 140401, Punjab, India [ORCID]
Hasan MA: Faculty of Medicine and Pharmacy, University of Oradea, P-ta 1 Decembrie 10, 410087 Oradea, Romania
Cavalu S: Faculty of Medicine and Pharmacy, University of Oradea, P-ta 1 Decembrie 10, 410087 Oradea, Romania [ORCID]
Journal Name
Processes
Volume
10
Issue
2
First Page
426
Year
2022
Publication Date
2022-02-21
ISSN
2227-9717
Version Comments
Original Submission
Other Meta
PII: pr10020426, Publication Type: Review
Record Map
Published Article
LAPSE:2023.3092
This Record
External Link
https://doi.org/10.3390/pr10020426
Publisher Version
Download
Meta
Record Statistics
Record Views
199
Version History
[v1] (Original Submission)
Feb 21, 2023
Verified by curator on
Feb 21, 2023
This Version Number
v1
Citations
Most Recent
This Version
URL Here
https://psecommunity.org/LAPSE:2023.3092
Record Owner
Auto Uploader for LAPSE
Links to Related Works