In recent years, there has been dynamic changes in the industrial environment as a result of further innovations called Industry 4.0 (I.4.0), especially in the field of digital technology and manufacturing. Despite numerous examples of the implementation of Industry 4.0 in enterprises, there is no general framework for the implementation of Industry 4.0 with a detailed schedule. Researching the ways of implementing Industry 4.0 is still a current and unexplored area of research. The main aim of the paper is to present the concept of the theoretical framework for Industry 4.0 implementation based on selected schedules of the Industry 4.0 implementation. The paper was based on information from literature review and analysis of pilot enterprise projects to Industry 4.0 (case study) that were conducted in selected enterprises. The paper presents the key components of the framework of Industry 4.0 and the basic stage of implementing the concept in the enterprises, paying attention to their sequence and time frames. The proposed approach is dedicated to researchers and practitioners who implement the concept of Industry 4.0 in enterprises.