LAPSE:2023.24956
Published Article
LAPSE:2023.24956
A Critical Review on the Synthesis of Natural Sodium Alginate Based Composite Materials: An Innovative Biological Polymer for Biomedical Delivery Applications
March 28, 2023
Abstract
Sodium alginate (Na-Alg) is water-soluble, neutral, and linear polysaccharide. It is the derivative of alginic acid which comprises 1,4-β-d-mannuronic (M) and α-l-guluronic (G) acids and has the chemical formula (NaC6H7O6). It shows water-soluble, non-toxic, biocompatible, biodegradable, and non-immunogenic properties. It had been used for various biomedical applications, among which the most promising are drug delivery, gene delivery, wound dressing, and wound healing. For different biomedical applications, it is used in different forms with the help of new techniques. That is the reason it had been blended with different polymers. In this review article, we present a comprehensive overview of the combinations of sodium alginate with natural and synthetic polymers and their biomedical applications involving delivery systems. All the scientific/technical issues have been addressed, and we have highlighted the recent advancements.
Sodium alginate (Na-Alg) is water-soluble, neutral, and linear polysaccharide. It is the derivative of alginic acid which comprises 1,4-β-d-mannuronic (M) and α-l-guluronic (G) acids and has the chemical formula (NaC6H7O6). It shows water-soluble, non-toxic, biocompatible, biodegradable, and non-immunogenic properties. It had been used for various biomedical applications, among which the most promising are drug delivery, gene delivery, wound dressing, and wound healing. For different biomedical applications, it is used in different forms with the help of new techniques. That is the reason it had been blended with different polymers. In this review article, we present a comprehensive overview of the combinations of sodium alginate with natural and synthetic polymers and their biomedical applications involving delivery systems. All the scientific/technical issues have been addressed, and we have highlighted the recent advancements.
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Keywords
biomedical application, biomedical delivery, gene delivery, natural polymer, sodium alginate
Subject
Suggested Citation
Ahmad A, Mubarak N, Jannat FT, Ashfaq T, Santulli C, Rizwan M, Najda A, Bin-Jumah M, Abdel-Daim MM, Hussain S, Ali S. A Critical Review on the Synthesis of Natural Sodium Alginate Based Composite Materials: An Innovative Biological Polymer for Biomedical Delivery Applications. (2023). LAPSE:2023.24956
Author Affiliations
Ahmad A: Department of Chemistry, The University of Lahore, Lahore 54590, Pakistan [ORCID]
Mubarak N: Department of Chemical Engineering, Faculty of Engineering and Science, Curtin University, Sarawak 98009, Malaysia [ORCID]
Jannat FT: Department of Chemistry, Government College University, Faisalabad 38000, Pakistan
Ashfaq T: Department of Chemistry, Government College University, Faisalabad 38000, Pakistan
Santulli C: School of Science and Technology Geology Division (SST), Università Degli Studi di Camerino, Via Gentile III da Varano, 62032 Camerino, Italy [ORCID]
Rizwan M: Department of Environmental Science and Engineering, Government College University, Faisalabad 38000, Pakistan [ORCID]
Najda A: Laboratory of Quality of Vegetables and Medicinal Plants, Department of Vegetable Crops and Medicinal Plants, University of Life Sciences in Lublin, 15 Akademicka Street, 20-950 Lublin, Poland [ORCID]
Bin-Jumah M: Biology Department, College of Science, Princess Nourah bint Abdulrahman University, Riyadh 11564, Saudi Arabia [ORCID]
Abdel-Daim MM: Department of Zoology, Science College, King Saud University, Riyadh 11451, Saudi Arabia; Pharmacology Department, Faculty of Veterinary Medicine, Suez Canal University, Ismailia 41522, Egypt [ORCID]
Hussain S: School of Materials Science and Engineering, Jiangsu University, Zhenjiang 212013, China [ORCID]
Ali S: Department of Environmental Science and Engineering, Government College University, Faisalabad 38000, Pakistan; Department of Biological Sciences and Technology, China Medical University (CMU), Taichung 40402, Taiwan [ORCID]
Mubarak N: Department of Chemical Engineering, Faculty of Engineering and Science, Curtin University, Sarawak 98009, Malaysia [ORCID]
Jannat FT: Department of Chemistry, Government College University, Faisalabad 38000, Pakistan
Ashfaq T: Department of Chemistry, Government College University, Faisalabad 38000, Pakistan
Santulli C: School of Science and Technology Geology Division (SST), Università Degli Studi di Camerino, Via Gentile III da Varano, 62032 Camerino, Italy [ORCID]
Rizwan M: Department of Environmental Science and Engineering, Government College University, Faisalabad 38000, Pakistan [ORCID]
Najda A: Laboratory of Quality of Vegetables and Medicinal Plants, Department of Vegetable Crops and Medicinal Plants, University of Life Sciences in Lublin, 15 Akademicka Street, 20-950 Lublin, Poland [ORCID]
Bin-Jumah M: Biology Department, College of Science, Princess Nourah bint Abdulrahman University, Riyadh 11564, Saudi Arabia [ORCID]
Abdel-Daim MM: Department of Zoology, Science College, King Saud University, Riyadh 11451, Saudi Arabia; Pharmacology Department, Faculty of Veterinary Medicine, Suez Canal University, Ismailia 41522, Egypt [ORCID]
Hussain S: School of Materials Science and Engineering, Jiangsu University, Zhenjiang 212013, China [ORCID]
Ali S: Department of Environmental Science and Engineering, Government College University, Faisalabad 38000, Pakistan; Department of Biological Sciences and Technology, China Medical University (CMU), Taichung 40402, Taiwan [ORCID]
Journal Name
Processes
Volume
9
Issue
1
First Page
pr9010137
Year
2021
Publication Date
2021-01-11
ISSN
2227-9717
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PII: pr9010137, Publication Type: Review
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LAPSE:2023.24956
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https://doi.org/10.3390/pr9010137
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Mar 28, 2023
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