LAPSE:2023.24736
Published Article

LAPSE:2023.24736
Drug Carriers: Classification, Administration, Release Profiles, and Industrial Approach
March 28, 2023
Abstract
This work is aimed at providing a description of the complex world of drug carriers, starting from the description of this particular market in terms of revenue. Then, a brief overview of several types of conventional and innovative drug carrier systems has been included. The types of administration routes were also analyzed, with a critical and qualitative comment on drug release kinetics and drug profile shapes. Carriers were classified according to their ability to provide a prolonged and targeted release. The concept of the therapeutic window has been presented, providing advantages of having pulsed drug release to avoid side effects to target tissues. A critical comment on the use of conventional and innovative techniques for the production of drug carriers by large industrial companies has been proposed. As a final attempt for this work, an overall unique schematization of a drug carrier production process has been added, highlighting the necessity to create a strong double link among world-requested versatility of drug carriers for human applications and the newly developed industrial processes.
This work is aimed at providing a description of the complex world of drug carriers, starting from the description of this particular market in terms of revenue. Then, a brief overview of several types of conventional and innovative drug carrier systems has been included. The types of administration routes were also analyzed, with a critical and qualitative comment on drug release kinetics and drug profile shapes. Carriers were classified according to their ability to provide a prolonged and targeted release. The concept of the therapeutic window has been presented, providing advantages of having pulsed drug release to avoid side effects to target tissues. A critical comment on the use of conventional and innovative techniques for the production of drug carriers by large industrial companies has been proposed. As a final attempt for this work, an overall unique schematization of a drug carrier production process has been added, highlighting the necessity to create a strong double link among world-requested versatility of drug carriers for human applications and the newly developed industrial processes.
Record ID
Keywords
aerogels, dendrimers, drug carriers, drug delivery, hydrogels, liposomes, nanocapsules, nanoparticles, niosomes, quantum dots
Subject
Suggested Citation
Trucillo P. Drug Carriers: Classification, Administration, Release Profiles, and Industrial Approach. (2023). LAPSE:2023.24736
Author Affiliations
Trucillo P: Department of Chemical, Material and Industrial Production Engineering (DICMAPI), University of Naples Federico II, Piazzale Vincenzo Tecchio 90, 80125 Napoli (NA), Italy [ORCID]
Journal Name
Processes
Volume
9
Issue
3
First Page
470
Year
2021
Publication Date
2021-03-06
ISSN
2227-9717
Version Comments
Original Submission
Other Meta
PII: pr9030470, Publication Type: Review
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Published Article

LAPSE:2023.24736
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https://doi.org/10.3390/pr9030470
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[v1] (Original Submission)
Mar 28, 2023
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Mar 28, 2023
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