LAPSE:2023.0168
Published Article

LAPSE:2023.0168
Optimization of Glycerol Extraction of Chlorogenic Acid from Honeysuckle by Response Surface Methodology
February 17, 2023
Abstract
Using honeysuckle as raw material, chlorogenic acid (CGA) was extracted with different alcohols. Based on the single-factor experiment design, the relationship between each parameter and the response value was explored by Box−Behnken method to optimize the process conditions. Best extraction results were obtained under the conditions of solid-to-liquid ratio of 1:20, the ultrasonic time of 40 min, the ultrasonic vibrator power of 240 w, and the CGA extraction rate of 2.98%. The experimental data show that the extraction rate of CGA is related to the length of the alcohol carbon chain and the number of hydroxyl groups in the extractant. The results from this work can provide technical basis for the safe and efficient production of CGA from honeysuckle.
Using honeysuckle as raw material, chlorogenic acid (CGA) was extracted with different alcohols. Based on the single-factor experiment design, the relationship between each parameter and the response value was explored by Box−Behnken method to optimize the process conditions. Best extraction results were obtained under the conditions of solid-to-liquid ratio of 1:20, the ultrasonic time of 40 min, the ultrasonic vibrator power of 240 w, and the CGA extraction rate of 2.98%. The experimental data show that the extraction rate of CGA is related to the length of the alcohol carbon chain and the number of hydroxyl groups in the extractant. The results from this work can provide technical basis for the safe and efficient production of CGA from honeysuckle.
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Keywords
chlorogenic acid, glycerol, honeysuckle, response surface methodology, ultrasonic assisted extraction
Subject
Suggested Citation
Luo M, Liu X, Zhao Z, Wang F, Shao C. Optimization of Glycerol Extraction of Chlorogenic Acid from Honeysuckle by Response Surface Methodology. (2023). LAPSE:2023.0168
Author Affiliations
Luo M: Beijing Institute of Petrochemical Technology, Beijing 102617, China; Beijing Key Laboratory of Fuels Cleaning and Advanced Catalytic Emission Reduction Technology, Beijing 102617, China [ORCID]
Liu X: Beijing Institute of Petrochemical Technology, Beijing 102617, China; Beijing Key Laboratory of Fuels Cleaning and Advanced Catalytic Emission Reduction Technology, Beijing 102617, China
Zhao Z: Beijing Institute of Petrochemical Technology, Beijing 102617, China; Beijing Key Laboratory of Fuels Cleaning and Advanced Catalytic Emission Reduction Technology, Beijing 102617, China
Wang F: Beijing Institute of Petrochemical Technology, Beijing 102617, China; Beijing Key Laboratory of Fuels Cleaning and Advanced Catalytic Emission Reduction Technology, Beijing 102617, China
Shao C: Beijing Institute of Petrochemical Technology, Beijing 102617, China; Beijing Key Laboratory of Fuels Cleaning and Advanced Catalytic Emission Reduction Technology, Beijing 102617, China
Liu X: Beijing Institute of Petrochemical Technology, Beijing 102617, China; Beijing Key Laboratory of Fuels Cleaning and Advanced Catalytic Emission Reduction Technology, Beijing 102617, China
Zhao Z: Beijing Institute of Petrochemical Technology, Beijing 102617, China; Beijing Key Laboratory of Fuels Cleaning and Advanced Catalytic Emission Reduction Technology, Beijing 102617, China
Wang F: Beijing Institute of Petrochemical Technology, Beijing 102617, China; Beijing Key Laboratory of Fuels Cleaning and Advanced Catalytic Emission Reduction Technology, Beijing 102617, China
Shao C: Beijing Institute of Petrochemical Technology, Beijing 102617, China; Beijing Key Laboratory of Fuels Cleaning and Advanced Catalytic Emission Reduction Technology, Beijing 102617, China
Journal Name
Processes
Volume
11
Issue
1
First Page
110
Year
2022
Publication Date
2022-12-30
ISSN
2227-9717
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Original Submission
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PII: pr11010110, Publication Type: Journal Article
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LAPSE:2023.0168
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https://doi.org/10.3390/pr11010110
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[v1] (Original Submission)
Feb 17, 2023
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Feb 17, 2023
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