LAPSE:2020.1274
Published Article
LAPSE:2020.1274
Process Optimization for Green Synthesis of Silver Nanoparticles Using Indonesian Medicinal Plant Extracts
Kartini Kartini, Amarisa Alviani, Dia Anjarwati, Adinda Finna Fanany, Johan Sukweenadhi, Christina Avanti
December 22, 2020
Silver nanoparticles (AgNPs) are an interesting metal nanoparticle that can be incorporated into pharmaceutical products, including for diabetic foot ulcers as an antimicrobial agent. Green synthesis of AgNPs using plant extracts has been drawing much attention as it is simple, eco-friendly, stable, and cost-effective. This present study was performed to evaluate the potential of three Indonesian medicinal plant extracts, namely Phyllanthus niruri (PN), Orthosiphon stamineus (OS), and Curcuma longa (CL), as reducing and capping agents in the green synthesis of AgNPs, and to optimize their concentrations. Based on the yields and characteristics of the formed nanoparticles, which were analyzed using a UV-Vis spectrophotometer, particle size analyzer, scanning electron microscope, and X-ray diffractometer, Phyllanthus niruri extract at a concentration of 0.5% was concluded as the best extract in the green synthesis of AgNPs. It is thereby a prospective reducing and capping agent for further scale-up studies.
Keywords
Curcuma longa, green synthesis, Orthosiphon stamineus, Phyllanthus niruri, silver nanoparticles
Suggested Citation
Kartini K, Alviani A, Anjarwati D, Fanany AF, Sukweenadhi J, Avanti C. Process Optimization for Green Synthesis of Silver Nanoparticles Using Indonesian Medicinal Plant Extracts. (2020). LAPSE:2020.1274
Author Affiliations
Kartini K: Department of Pharmaceutical Biology, Faculty of Pharmacy, University of Surabaya, Jl. Raya Kalirungkut, Surabaya 60293, Indonesia
Alviani A: Department of Pharmaceutical Biology, Faculty of Pharmacy, University of Surabaya, Jl. Raya Kalirungkut, Surabaya 60293, Indonesia
Anjarwati D: Department of Pharmaceutical Biology, Faculty of Pharmacy, University of Surabaya, Jl. Raya Kalirungkut, Surabaya 60293, Indonesia
Fanany AF: Department of Pharmaceutics, Faculty of Pharmacy, University of Surabaya, Jl. Raya Kalirungkut, Surabaya 60293, Indonesia
Sukweenadhi J: Faculty of Biotechnology, University of Surabaya, Jl. Raya Kalirungkut, Surabaya 60293, Indonesia
Avanti C: Department of Pharmaceutics, Faculty of Pharmacy, University of Surabaya, Jl. Raya Kalirungkut, Surabaya 60293, Indonesia
Journal Name
Processes
Volume
8
Issue
8
Article Number
E998
Year
2020
Publication Date
2020-08-17
Published Version
ISSN
2227-9717
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Original Submission
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PII: pr8080998, Publication Type: Journal Article
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LAPSE:2020.1274
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doi:10.3390/pr8080998
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Dec 22, 2020
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CC BY 4.0
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Dec 22, 2020
 
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Dec 22, 2020
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Original Submitter
Calvin Tsay
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