LAPSE:2020.0827
Published Article
LAPSE:2020.0827
Synthesis and Characterization of New Lithium and Boron Based Metal Organic Frameworks with NLO Properties for Application in Neutron Capture Therapy
July 17, 2020
In this work, we synthetized and characterized new crystalline materials with theranostic properties, i.e., they can be used both as bio-sensors and for “drug delivery”. The two solid crystalline compounds studied are Metal Organic Frameworks and have formulas Li[(C6H12O6)2B]·2H2O and Li[(C4H2O6)2B]·5.5H2O. They can be synthetized both with natural isotopes of Li and B or with 6Li and 10B isotopes, that can be explored for Neutron Capture Therapy (NCT) for anti-cancer treatment. The presence of chiral organic molecules, such as mannitol and tartaric acid, provides the NLO property to the crystals and thus their capability to generate the Second Harmonic, which is useful for applications as bio-sensors. The two compounds were characterized with X-ray Diffraction and the Second Harmonic Generation (SHG) responses were estimated by theoretical calculations, and the results were compared with experimental measurements of powdered samples. In order to test the behavior of such compounds under thermal neutron irradiation, we preliminary exposed one of the two compounds in the e_LiBANS facility at the Torino Physics Department. Preliminary results are reported.
Record ID
Keywords
ab-initio calculations, metal organic frameworks, neutron capture therapy, NLO properties, SHG efficiency
Subject
Suggested Citation
Marabello D, Benzi P, Beccari F, Canepa C, Cariati E, Cioci A, Costa M, Durisi EA, Monti V, Sans Planell O, Antoniotti P. Synthesis and Characterization of New Lithium and Boron Based Metal Organic Frameworks with NLO Properties for Application in Neutron Capture Therapy. (2020). LAPSE:2020.0827
Author Affiliations
Marabello D: Dipartimento di Chimica, University of Torino, Via P. Giuria 7, 10125 Torino, Italy; CrisDi—Interdepartmental Center for Crystallography, University of Torino, Via P. Giuria 7, 10125 Torino, Italy [ORCID]
Benzi P: Dipartimento di Chimica, University of Torino, Via P. Giuria 7, 10125 Torino, Italy; CrisDi—Interdepartmental Center for Crystallography, University of Torino, Via P. Giuria 7, 10125 Torino, Italy
Beccari F: Dipartimento di Chimica, University of Torino, Via P. Giuria 7, 10125 Torino, Italy
Canepa C: Dipartimento di Chimica, University of Torino, Via P. Giuria 7, 10125 Torino, Italy
Cariati E: Dipartimento di Chimica, University of Milano, via Golgi 19, 20133 Milano, Italy [ORCID]
Cioci A: Dipartimento di Chimica, University of Torino, Via P. Giuria 7, 10125 Torino, Italy
Costa M: Dipartimento di Fisica, University of Torino, via P. Giuria 1, 10125 Torino, Italy
Durisi EA: Dipartimento di Fisica, University of Torino, via P. Giuria 1, 10125 Torino, Italy
Monti V: Dipartimento di Fisica, University of Torino, via P. Giuria 1, 10125 Torino, Italy [ORCID]
Sans Planell O: Dipartimento di Fisica, University of Torino, via P. Giuria 1, 10125 Torino, Italy [ORCID]
Antoniotti P: Dipartimento di Chimica, University of Torino, Via P. Giuria 7, 10125 Torino, Italy; CrisDi—Interdepartmental Center for Crystallography, University of Torino, Via P. Giuria 7, 10125 Torino, Italy
Benzi P: Dipartimento di Chimica, University of Torino, Via P. Giuria 7, 10125 Torino, Italy; CrisDi—Interdepartmental Center for Crystallography, University of Torino, Via P. Giuria 7, 10125 Torino, Italy
Beccari F: Dipartimento di Chimica, University of Torino, Via P. Giuria 7, 10125 Torino, Italy
Canepa C: Dipartimento di Chimica, University of Torino, Via P. Giuria 7, 10125 Torino, Italy
Cariati E: Dipartimento di Chimica, University of Milano, via Golgi 19, 20133 Milano, Italy [ORCID]
Cioci A: Dipartimento di Chimica, University of Torino, Via P. Giuria 7, 10125 Torino, Italy
Costa M: Dipartimento di Fisica, University of Torino, via P. Giuria 1, 10125 Torino, Italy
Durisi EA: Dipartimento di Fisica, University of Torino, via P. Giuria 1, 10125 Torino, Italy
Monti V: Dipartimento di Fisica, University of Torino, via P. Giuria 1, 10125 Torino, Italy [ORCID]
Sans Planell O: Dipartimento di Fisica, University of Torino, via P. Giuria 1, 10125 Torino, Italy [ORCID]
Antoniotti P: Dipartimento di Chimica, University of Torino, Via P. Giuria 7, 10125 Torino, Italy; CrisDi—Interdepartmental Center for Crystallography, University of Torino, Via P. Giuria 7, 10125 Torino, Italy
Journal Name
Processes
Volume
8
Issue
5
Article Number
E558
Year
2020
Publication Date
2020-05-09
Published Version
ISSN
2227-9717
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Original Submission
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PII: pr8050558, Publication Type: Journal Article
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LAPSE:2020.0827
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doi:10.3390/pr8050558
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[v1] (Original Submission)
Jul 17, 2020
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Jul 17, 2020
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https://psecommunity.org/LAPSE:2020.0827
Original Submitter
Calvin Tsay
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