Face-centered cubic lattice F C C ( n ) has received extensive consideration as of late, inferable from its recognized properties and non-poisonous nature, minimal effort, plenitude, and basic creation process. The graph of a face-centered cubic cross-section contains cube points and face centres. A topological index of a molecular graph G is a numeric amount identified with G, which depicts its topological properties. In this paper, using graph theory tools, we computed the molecular descriptors (topological indices)—to be specific, Zagreb-type indices, a forgotten index, a Balaban index, the fourth version of an atom−bond connectivity index, and the fifth version of a geometric arithmetic index for face-centered cubic lattice F C C ( n ) .