LAPSE:2020.1116
Published Article
LAPSE:2020.1116
EEG Synchronization Analysis for Seizure Prediction: A Study on Data of Noninvasive Recordings
Paolo Detti, Giampaolo Vatti, Garazi Zabalo Manrique de Lara
November 9, 2020
Objective: Epilepsy is a neurological disorder arising from anomalies of the electrical activity in the brain, affecting ~65 million individuals worldwide. Prediction methods, typically based on machine learning methods, require a large amount of data for training, in order to correctly classify seizures with small false alarm rates. Methods: In this work, we present a new database containing EEG scalp signals of 14 epileptic patients acquired at the Unit of Neurology and Neurophysiology of the University of Siena, Italy. Furthermore, a patient-specific seizure prediction method, based on the detection of synchronization patterns in the EEG, is proposed and tested on the data of the database. The use of noninvasive EEG data aims to explore the possibility of developing a noninvasive monitoring/control device for the prediction of seizures. The prediction method employs synchronization measures computed over all channel pairs and a computationally inexpensive threshold-based classification approach. Results and conclusions: The experimental analysis, performed by inspection and by the proposed threshold-based classifier on all the patients of the database, shows that the features extracted by the synchronization measures are able to detect preictal and ictal states and allow the prediction of the seizures few minutes before the seizure onsets.
Keywords
data classification, EEG data, epilepsy, synchronization measures, threshold-based classifier
Suggested Citation
Detti P, Vatti G, Zabalo Manrique de Lara G. EEG Synchronization Analysis for Seizure Prediction: A Study on Data of Noninvasive Recordings. (2020). LAPSE:2020.1116
Author Affiliations
Detti P: Department of Information Engineering and Mathematics, University of Siena, 53100 Siena, Italy [ORCID]
Vatti G: Department of Medicine, Surgery and Neuroscience, University of Siena, 53100 Siena, Italy
Zabalo Manrique de Lara G: Department of Information Engineering and Mathematics, University of Siena, 53100 Siena, Italy
Journal Name
Processes
Volume
8
Issue
7
Article Number
E846
Year
2020
Publication Date
2020-07-16
Published Version
ISSN
2227-9717
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Original Submission
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PII: pr8070846, Publication Type: Journal Article
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LAPSE:2020.1116
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doi:10.3390/pr8070846
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Nov 9, 2020
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CC BY 4.0
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Original Submitter
Calvin Tsay
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