ITU-T G.9904 standard, also known as PoweRline Intelligent Metering Evolution (PRIME), is a Power Line Communications standard for advanced metering, grid control and asset monitoring defined by the International Telecommunication Union (ITU). In this paper, an analysis about how different characteristics of the communication channel and types of noise might affect the system performance is carried out. This study is based on simulations of the PRIME physical layer using different channel characteristics and transmission parameters. The conclusions obtained are very valuable for better understanding the behavior of the ITU-T G.9904 (PRIME) standard in the field, allowing future improvements in deployment strategies and equipment design.