LAPSE:2025.0593
Model
LAPSE:2025.0593
A Stochastic Agent-based Model for Naive CD8+ T Cell Recirculation Dynamics in Mice
September 5, 2025
Abstract
This is the source code written in MATLAB for the stochastic, agent-based model for naive CD8+ T cell recirculation dynamics in mice. The model simulates the migration of naive CD8+ T cells between the blood and major lymphoid tissues in the body for 47 hours post i.v. transfer. It is also capable of predicting the effect of an immunosuppressant drug FTY720 on blocking naive CD8+ T cell egress from lymph nodes.
Keywords
Agent-based model, Naive T cells, Stochastic modeling, Systems immunology, T cell dynamics
Subject
Suggested Citation
Elrefaei N, Christian DA, Adams TA II. A Stochastic Agent-based Model for Naive CD8+ T Cell Recirculation Dynamics in Mice. (2025). LAPSE:2025.0593
Author Affiliations
Elrefaei N: McMaster University [ORCID] [Google Scholar]
Christian DA: University of Pennsylvania [ORCID] [Google Scholar]
Adams TA II: Norwegian University of Science and Technology [ORCID] [Google Scholar]
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Publication Date
2025-09-02
Version Comments
Original Submission
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Sep 5, 2025
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[v1] (Original Submission)
Sep 5, 2025
 
Verified by curator on
Sep 8, 2025
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v1
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https://psecommunity.org/LAPSE:2025.0593
 
Record Owner
NElrefaei