This paper presents an on-line diagnosis method for large photovoltaic (PV) power plants by using a machine learning algorithm. Most renewable energy output power is decreased due to the lack of management tools and the skills of maintenance engineers. Additionally, many photovoltaic power plants have a long down-time due to the absence of a monitoring system and their distance from the city. The IEC 61724-1 standard is a Performance Ratio (PR) index that evaluates the PV power plant performance and reliability. However, the PR index has a low recognition rate of the fault state in conditions of low irradiation and bad weather. This paper presents a weather-corrected index, linear regression method, temperature correction equation, estimation error matrix, clearness index and proposed variable index, as well as a one-class Support Vector Machine (SVM) method and a kernel technique to classify the fault state and anomaly output power of PV plants.