The study presented in the paper is an innovative research approach. It is the result of linking the concept of supply chain management and global changes, which at present are clearly visible on a global scale, with research methodology based on the systematic literature review, knowledge visualization and an expert method that makes use of knowledge, experience and opinions of experts in a given field. This research is about a Delphi study that was conducted in the context of the development of trends of supply chain and global changes, based on the findings of a systematic literature review. The qualitative study was conducted with 30 Delphi experts in the field of the supply chain. This progressive approach to the research topic allowed us to discover key global trends and modern supply chain development directions in the context of global changes, as well as their assessment and projection of the developmental potential of these trends.