Optimization and Validation of an Extraction Method for Endosulfan Lactone on a Solid Substrate

Paola T. Vázquez-Villegas; Rocío Meza-Gordillo; María C. Luján-Hidalgo; Abumalé Cruz-Salomón; Víctor M. Ruíz-Valdiviezo; Federico A. Gutiérrez-Miceli; Juan J. Villalobos-Maldonado; Joaquín A. Montes-Molina

LAPSE

Living Archive for Process Systems Engineering

LAPSE:2022.0134

Published Article

LAPSE:2022.0134

Optimization and Validation of an Extraction Method for Endosulfan Lactone on a Solid Substrate

Paola T. Vázquez-Villegas, Rocío Meza-Gordillo, María C. Luján-Hidalgo, Abumalé Cruz-Salomón, Víctor M. Ruíz-Valdiviezo, Federico A. Gutiérrez-Miceli, Juan J. Villalobos-Maldonado, Joaquín A. Montes-Molina

November 6, 2022

Endosulfan lactone is a metabolite obtained from the biological oxidation of the insecticide endosulfan by action of the microorganisms present in the soil. This metabolite is more toxic and persistent than the parent compound. Therefore, it is extremely important to be able to determine the presence of this metabolite in the soil. However, accessible methods for extraction of endosulfan lactone in soil were not found in published literature. For this reason, the aim of this study was to evaluate two conventional methods of liquid−solid extraction for the determination of endosulfan lactone in solid substrate using two solvents (ethyl acetate and acetonitrile) and HPLC UV-VIS. The acetonitrile and rotary agitation extraction method was the one with the highest efficiency (97%), optimized using a factorial 32 response surface design, and validated in terms of linearity and precision. The linearity shown was r > 0.999 in a wide spike level (0.15−100 mg kg−1), with the detection limit (DL) of 0.045 mg kg−1 and quantification limit (QL) of 0.15 mg kg−1. The extraction of endosulfan lactone in solid substrate using acetonitrile was more efficient than that used with ethyl acetate, so this method could be used to extract and quantify endosulfan lactone in agricultural soil.

Record ID

LAPSE:2022.0134

Keywords

endosulfan lactone, HPLC UV-VIS, Optimization, response surface, solvent extraction, ultrasound

Subject

Optimization

Suggested Citation

Vázquez-Villegas PT, Meza-Gordillo R, Luján-Hidalgo MC, Cruz-Salomón A, Ruíz-Valdiviezo VM, Gutiérrez-Miceli FA, Villalobos-Maldonado JJ, Montes-Molina JA. Optimization and Validation of an Extraction Method for Endosulfan Lactone on a Solid Substrate. (2022). LAPSE:2022.0134

Author Affiliations

Vázquez-Villegas PT: Departamento de Ingeniería en Industrias Alimentarias, Tecnológico Nacional de México/ITS de Cintalapa, Carretera Panamericana km 995, Cintalapa de Figueroa 30400, Chiapas, Mexico
Meza-Gordillo R: Departamento de Ingeniería Química y Bioquímica, Tecnológico Nacional de México/IT de Tuxtla Gutiérrez, Carretera Panamericana km 1080, Tuxtla Gutiérrez 29050, Chiapas, Mexico
Luján-Hidalgo MC: Departamento de Ingeniería Química y Bioquímica, Tecnológico Nacional de México/IT de Tuxtla Gutiérrez, Carretera Panamericana km 1080, Tuxtla Gutiérrez 29050, Chiapas, Mexico
Cruz-Salomón A: Escuela de Ciencias Químicas, sede Ocozocoautla, Universidad Autónoma de Chiapas (UNACH), Carretera Panamericana Ocozocoautla—Cintalapa km 2.5, Ocozocoautla de Espinosa 29140, Chiapas, Mexico [ORCID]
Ruíz-Valdiviezo VM: Departamento de Ingeniería Química y Bioquímica, Tecnológico Nacional de México/IT de Tuxtla Gutiérrez, Carretera Panamericana km 1080, Tuxtla Gutiérrez 29050, Chiapas, Mexico [ORCID]
Gutiérrez-Miceli FA: Departamento de Ingeniería Química y Bioquímica, Tecnológico Nacional de México/IT de Tuxtla Gutiérrez, Carretera Panamericana km 1080, Tuxtla Gutiérrez 29050, Chiapas, Mexico [ORCID]
Villalobos-Maldonado JJ: Departamento de Ingeniería Química y Bioquímica, Tecnológico Nacional de México/IT de Tuxtla Gutiérrez, Carretera Panamericana km 1080, Tuxtla Gutiérrez 29050, Chiapas, Mexico
Montes-Molina JA: Departamento de Ingeniería Química y Bioquímica, Tecnológico Nacional de México/IT de Tuxtla Gutiérrez, Carretera Panamericana km 1080, Tuxtla Gutiérrez 29050, Chiapas, Mexico

Journal Name

Processes

Volume

9

Issue

2

First Page

284

Year

2021

Publication Date

2021-02-02