LAPSE:2021.0639
Published Article
LAPSE:2021.0639
Recombinant Technologies to Improve Ruminant Production Systems: The Past, Present and Future
Andres Alfredo Pech-Cervantes, Muhammad Irfan, Zaira Magdalena Estrada-Reyes, Ibukun Michael Ogunade
July 26, 2021
The use of recombinant technologies has been proposed as an alternative to improve livestock production systems for more than 25 years. However, its effects on animal health and performance have not been described. Thus, understanding the use of recombinant technology could help to improve public acceptance. The objective of this review is to describe the effects of recombinant technologies and proteins on the performance, health status, and rumen fermentation of meat and milk ruminants. The heterologous expression and purification of proteins mainly include eukaryotic and prokaryotic systems like Escherichia coli and Pichia pastoris. Recombinant hormones have been commercially available since 1992, their effects remarkably improving both the reproductive and productive performance of animals. More recently the use of recombinant antigens and immune cells have proven to be effective in increasing meat and milk production in ruminant production systems. Likewise, the use of recombinant vaccines could help to reduce drug resistance developed by parasites and improve animal health. Recombinant enzymes and probiotics could help to enhance rumen fermentation and animal efficiency. Likewise, the use of recombinant technologies has been extended to the food industry as a strategy to enhance the organoleptic properties of animal-food sources, reduce food waste and mitigate the environmental impact. Despite these promising results, many of these recombinant technologies are still highly experimental. Thus, the feasibility of these technologies should be carefully addressed before implementation. Alternatively, the use of transgenic animals and the development of genome editing technology has expanded the frontiers in science and research. However, their use and implementation depend on complex policies and regulations that are still under development.
Keywords
hormone, recombinant proteins, ruminants, vaccine
Suggested Citation
Pech-Cervantes AA, Irfan M, Estrada-Reyes ZM, Ogunade IM. Recombinant Technologies to Improve Ruminant Production Systems: The Past, Present and Future. (2021). LAPSE:2021.0639
Author Affiliations
Pech-Cervantes AA: Agricultural Research Station, Fort Valley State University, Fort Valley, GA 31030, USA [ORCID]
Irfan M: Department of Oral Biology, College of Dentistry, University of Florida, Gainesville, FL 32603, USA
Estrada-Reyes ZM: Agricultural Research Station, Fort Valley State University, Fort Valley, GA 31030, USA
Ogunade IM: Division of Animal and Nutritional Sciences, West Virginia University, Morgantown, WV 26505, USA [ORCID]
Journal Name
Processes
Volume
8
Issue
12
Article Number
E1633
Year
2020
Publication Date
2020-12-11
Published Version
ISSN
2227-9717
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Original Submission
Other Meta
PII: pr8121633, Publication Type: Review
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LAPSE:2021.0639
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doi:10.3390/pr8121633
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Jul 26, 2021
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CC BY 4.0
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Jul 26, 2021
 
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Jul 26, 2021
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Calvin Tsay
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