LAPSE:2020.0297
Published Article
LAPSE:2020.0297
Liquid Biphasic System: A Recent Bioseparation Technology
March 12, 2020
A well-known bioseparation technique namely liquid biphasic system (LBS) has attracted many researchers’ interest for being an alternative bioseparation technology for various kinds of biomolecules. The present review begins with an in-depth discussion on the fundamental principle of LBS and this is followed by the discussion on further development of various phase-forming components in LBS. Additionally, the implementation of various advance technologies to the LBS that is beneficial towards the efficiency of LBS for the extraction, separation, and purification of biomolecules was discussed. The key parameters affecting the LBS were presented and evaluated. Moreover, future prospect and challenges were highlighted to be a useful guide for future development of LBS. The efforts presented in this review will provide an insight for future researches in liquid-liquid separation techniques.
Record ID
Keywords
aqueous biphasic system, aqueous two-phase system, biomolecules, liquid biphasic system, purification, recovery, separation
Subject
Suggested Citation
Khoo KS, Leong HY, Chew KW, Lim JW, Ling TC, Show PL, Yen HW. Liquid Biphasic System: A Recent Bioseparation Technology. (2020). LAPSE:2020.0297
Author Affiliations
Khoo KS: Department of Chemical and Environmental Engineering, Faculty of Science and Engineering, University of Nottingham Malaysia, Jalan Broga, Semenyih 43500, Malaysia
Leong HY: College of Chemical and Biological Engineering, Zhejiang University, Hangzhou 310027, China
Chew KW: School of Mathematical Sciences, Faculty of Science and Engineering, University of Nottingham Malaysia, Jalan Broga, Semenyih 43500, Malaysia [ORCID]
Lim JW: Department of Fundamental and Applied Sciences, Centre for Biofuel and Biochemical Research, Institute of Self-Sustainable Building, Universiti Teknologi PETRONAS, 32610 Seri Iskandar, Malaysia [ORCID]
Ling TC: Institute of Biological Sciences, Faculty of Science, University of Malaya, Kuala Lumpur 50603, Malaysia
Show PL: Department of Chemical and Environmental Engineering, Faculty of Science and Engineering, University of Nottingham Malaysia, Jalan Broga, Semenyih 43500, Malaysia
Yen HW: Taipei Economic and Cultural Office, Prague, Czech Republic, Evropská 33C, 160 00 Praha 6, Czechia; Department of Chemical and Material Engineering, Tunghai University, Taiwan 407
Leong HY: College of Chemical and Biological Engineering, Zhejiang University, Hangzhou 310027, China
Chew KW: School of Mathematical Sciences, Faculty of Science and Engineering, University of Nottingham Malaysia, Jalan Broga, Semenyih 43500, Malaysia [ORCID]
Lim JW: Department of Fundamental and Applied Sciences, Centre for Biofuel and Biochemical Research, Institute of Self-Sustainable Building, Universiti Teknologi PETRONAS, 32610 Seri Iskandar, Malaysia [ORCID]
Ling TC: Institute of Biological Sciences, Faculty of Science, University of Malaya, Kuala Lumpur 50603, Malaysia
Show PL: Department of Chemical and Environmental Engineering, Faculty of Science and Engineering, University of Nottingham Malaysia, Jalan Broga, Semenyih 43500, Malaysia
Yen HW: Taipei Economic and Cultural Office, Prague, Czech Republic, Evropská 33C, 160 00 Praha 6, Czechia; Department of Chemical and Material Engineering, Tunghai University, Taiwan 407
Journal Name
Processes
Volume
8
Issue
2
Article Number
E149
Year
2020
Publication Date
2020-01-23
Published Version
ISSN
2227-9717
Version Comments
Original Submission
Other Meta
PII: pr8020149, Publication Type: Review
Record Map
Published Article
LAPSE:2020.0297
This Record
External Link
doi:10.3390/pr8020149
Publisher Version
Download
Meta
Record Statistics
Record Views
603
Version History
[v1] (Original Submission)
Mar 12, 2020
Verified by curator on
Mar 12, 2020
This Version Number
v1
Citations
Most Recent
This Version
URL Here
https://psecommunity.org/LAPSE:2020.0297
Original Submitter
Calvin Tsay
Links to Related Works