LAPSE:2021.0304
Published Article
LAPSE:2021.0304
Hydrodynamics and Mass Transfer Analysis in BioFlow® Bioreactor Systems
April 30, 2021
Biotechnological processes involving the presence of microorganisms are realized by using various types of stirred tanks or laboratory-scale dual-impeller commercial bioreactor. Hydrodynamics and mass transfer rate are crucial parameters describing the functionality and efficiency of bioreactors. Both parameters strictly depend on mixing applied during bioprocesses conducted in bioreactors. Establishing optimum hydrodynamics conditions for the realized process with microorganisms maximizes the yield of desired products. Therefore, our main objective was to analyze and define the main operational hydrodynamic parameters (including flow field, power consumption, mixing time, and mixing energy) and mass transfer process (in this case, gas−liquid transfer) of two different commercial bioreactors (BioFlo® 115 and BioFlo® 415). The obtained results are allowed using mathematical relationships to describe the analyzed processes that can be used to predict the mixing process and mass transfer ratio in BioFlo® bioreactors. The proposed correlations may be applied for the design of a scaled-up or scaled-down bioreactors.
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Subject
Suggested Citation
Kordas M, Konopacki M, Grygorcewicz B, Augustyniak A, Musik D, Wójcik K, Jędrzejczak-Silicka M, Rakoczy R. Hydrodynamics and Mass Transfer Analysis in BioFlow® Bioreactor Systems. (2021). LAPSE:2021.0304
Author Affiliations
Kordas M: Faculty of Chemical Technology and Engineering, West Pomeranian University of Technology in Szczecin, Piastów Avenue 42, 71-065 Szczecin, Poland
Konopacki M: Faculty of Chemical Technology and Engineering, West Pomeranian University of Technology in Szczecin, Piastów Avenue 42, 71-065 Szczecin, Poland [ORCID]
Grygorcewicz B: Department of Laboratory Medicine, Pomeranian Medical University in Szczecin, al. Powstańców Wielkopolskich 72, 70-111 Szczecin, Poland [ORCID]
Augustyniak A: Faculty of Chemical Technology and Engineering, West Pomeranian University of Technology in Szczecin, Piastów Avenue 42, 71-065 Szczecin, Poland; Chair of Building Materials and Construction Chemistry, Technische Universität Berlin, Gustav-Meyer-Allee 2 [ORCID]
Musik D: Faculty of Chemical Technology and Engineering, West Pomeranian University of Technology in Szczecin, Piastów Avenue 42, 71-065 Szczecin, Poland; ESC Global Sp. z o.o., Słoneczny Sad 4F, 72-002 Dołuje, Poland
Wójcik K: Faculty of Chemical Technology and Engineering, West Pomeranian University of Technology in Szczecin, Piastów Avenue 42, 71-065 Szczecin, Poland; ESC Global Sp. z o.o., Słoneczny Sad 4F, 72-002 Dołuje, Poland
Jędrzejczak-Silicka M: Faculty of Biotechnology and Animal Husbandry, West Pomeranian University of Technology in Szczecin, Janickiego Street 32, 71-270 Szczecin, Poland
Rakoczy R: Faculty of Chemical Technology and Engineering, West Pomeranian University of Technology in Szczecin, Piastów Avenue 42, 71-065 Szczecin, Poland [ORCID]
Konopacki M: Faculty of Chemical Technology and Engineering, West Pomeranian University of Technology in Szczecin, Piastów Avenue 42, 71-065 Szczecin, Poland [ORCID]
Grygorcewicz B: Department of Laboratory Medicine, Pomeranian Medical University in Szczecin, al. Powstańców Wielkopolskich 72, 70-111 Szczecin, Poland [ORCID]
Augustyniak A: Faculty of Chemical Technology and Engineering, West Pomeranian University of Technology in Szczecin, Piastów Avenue 42, 71-065 Szczecin, Poland; Chair of Building Materials and Construction Chemistry, Technische Universität Berlin, Gustav-Meyer-Allee 2 [ORCID]
Musik D: Faculty of Chemical Technology and Engineering, West Pomeranian University of Technology in Szczecin, Piastów Avenue 42, 71-065 Szczecin, Poland; ESC Global Sp. z o.o., Słoneczny Sad 4F, 72-002 Dołuje, Poland
Wójcik K: Faculty of Chemical Technology and Engineering, West Pomeranian University of Technology in Szczecin, Piastów Avenue 42, 71-065 Szczecin, Poland; ESC Global Sp. z o.o., Słoneczny Sad 4F, 72-002 Dołuje, Poland
Jędrzejczak-Silicka M: Faculty of Biotechnology and Animal Husbandry, West Pomeranian University of Technology in Szczecin, Janickiego Street 32, 71-270 Szczecin, Poland
Rakoczy R: Faculty of Chemical Technology and Engineering, West Pomeranian University of Technology in Szczecin, Piastów Avenue 42, 71-065 Szczecin, Poland [ORCID]
Journal Name
Processes
Volume
8
Issue
10
Article Number
E1311
Year
2020
Publication Date
2020-10-19
Published Version
ISSN
2227-9717
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Original Submission
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PII: pr8101311, Publication Type: Journal Article
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LAPSE:2021.0304
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doi:10.3390/pr8101311
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[v1] (Original Submission)
Apr 30, 2021
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Apr 30, 2021
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https://psecommunity.org/LAPSE:2021.0304
Original Submitter
Calvin Tsay
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